Rv0170

Tuberculist information
Gene namemce1B
Protein functionMce-family protein Mce1B
Functional category(tuberculist)virulence,detoxification and adaptaion
Gene location(kb)199.895
Molecular mass(da)37727.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 346
	  		  	1    MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFSNVSGLRQGQFVRASGV   60
			  	61   EIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYSDLIGNRYVELKRGEGKGAND  120
			  	121  LLPPGGLIPLSRTSPALDLDALIGGFKPVFRALDPAKVNNIANALITVFQGQGGTINDIL  180
			  	181  DQTAQLTSQIAERDQAIGEVVKNLNIVLDTTVKHRKEFDETVNNLENLITGLRNHSDQLA  240
			  	241  GGLAHISNGAGTVADLLAENRTLVRKAVSYLDAIQQPVIDQRVELDDLLHKTPTALTALG  300
			  	301  RANGTYGDFQNFYLCDLQIKWNGFQAGGPVRTVKLFSQPTGRCTPQ

Known structures in the PDB
No Known structures
1 35 69 103 137 171 205 239 273 307 341 Range: 35 to 113  |  Coverage: 22% MCE Range: 146 to 278  |  Coverage: 38% DUF3407 Range: 131 to 296  |  Coverage: 47% 1 Range: 48 to 120  |  Coverage: 20% 2
Number of amino acids : 346
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MCEPF0247035-113
DUF3407PF11887146-278
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
Model Number1
Profilea.63.1.1 - 1.20.120.20
Click for model details
zscore8.66
Residue begin131
Residue end296
Model Number2
Profileb.34.4.2 - 2.30.30.50
Click for model details
zscore4.05
Residue begin48
Residue end120
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0170Gene nameConfidence Score
Rv0167yrbE1A0.993
Rv0168yrbE1B0.975
Rv0174mce1F0.955
Rv0169mce1A0.941
Rv0169mce1A0.941
Rv0172mce1D0.934
Rv0177Rv01770.927
Rv0173lprK0.92
Rv0178Rv01780.916
Rv0171mce1C0.916
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions