Rv3265c

Tuberculist information
Gene namewbbL1
Protein functiondTDP-RHA:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase WbbL1 (alpha-L-rhamnose-(1->3)-alpha-D-GlcNAc(1->P)-P-decaprenyl)
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)3645.98
Molecular mass(da)33262.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 301
	  		  	1    VVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANL   60
			  	61   GYGTAVNRTIAQLGEMAGDAGEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALG  120
			  	121  PLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQERLEPSERPVGWLSGS  180
			  	181  CLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAHSTGRDPA  240
			  	241  SHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVRSSLRRSRRRKLKLVEGR  300
			  	301  H

Known structures in the PDB
No Known structures
1 31 61 91 121 151 181 211 241 271 301 Range: 1 to 245  |  Coverage: 81% Glyco_tranf_2_3 Range: 1 to 269  |  Coverage: 89% 1 Range: 1 to 245  |  Coverage: 81% 1
Number of amino acids : 301
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Glyco_tranf_2_3PF136411-245
Mtb Structural Proteome models
Model Number1
Model nameRv3265c
Template2FFU    APDBCREDO
Template coverage140_403
Template Identity(%)14.0
Model coverage(%)89.0
Normalized DOPE score-0.44

Structure Models from Chopin
Model Number1
Profilec.68.1.1 - 3.90.550.10
Click for model details
zscore17.6
Residue begin1
Residue end245
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3265cGene nameConfidence Score
Rv3266crmlD0.993
Rv0334rmlA0.972
Rv3464rmlB0.967
Rv3465rmlC0.955
Rv3264cmanB0.948
Rv3264cmanB0.948
Rv1525wbbL20.925
Rv1302rfe0.917
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions