SInCRe - Rv1302

Tuberculist information

Gene name	rfe
Protein function	Probable undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe (UDP-GlcNAc transferase)
Functional category(tuberculist)	cell wall and cell processes
Gene location(kb)	1458.3
Molecular mass(da)	42225
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 404

	  		  	1    VQYGLEVSSDVAGVAGGLLALSYRGAGVPLRELALVGLTAAIITYFATGPVRMLASRLGA   60
			  	61   VAYPRERDVHVTPTPRMGGLAMFLGIVGAVFLASQLPALTRGFVYSTGMPAVLVAGAVIM  120
			  	121  GIGLIDDRWGLDALTKFAGQITAASVLVTMGVAWSVLYIPVGGVGTIVLDQASSILLTLA  180
			  	181  LTVSIVNAMNFVDGLDGLAAGLGLITALAICMFSVGLLRDHGGDVLYYPPAVISVVLAGA  240
			  	241  CLGFLPHNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPISQNAYGARDVFALLSPFLLVV  300
			  	301  AVMFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRVVLIIYLWVGIVAFG  360
			  	361  AASSIFFNPRDTAAVMLGAIVVAGVATLIPLLRRGDDYYDPDLD

Known structures in the PDB

No Known structures

Number of amino acids : 404

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
Glycos_transf_4	PF00953	109-276

Mtb Structural Proteome models

Structure models not available for this query

Structure Models from Chopin

CHOPIN models not available for this query

Binding pockets

Structure models not available for this query

STRING

Cytoscape Web will replace the contents of this div with protein-protein interaction network.

Protein interacting with Rv1302	Gene name	Confidence Score
Rv3464	rmlB	0.952
Rv0334	rmlA	0.938
Rv3265c	wbbL1	0.917
Rv3465	rmlC	0.909

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

Chemical Name	Confidence score	Molecular Weight
undecaprenyl phosphatePubChem	0.974	847.282
UDP-GlcNAcPubChem	0.964	607.354
GlcNAc-pyrophosphorylundecaprenolPubChem	0.928	1130.45
UDP-N-acetyl-D-mannosaminuronic acidPubChem	0.921	621.337
UDP-N-acetyl-d-galactosaminuronic acidPubChem	0.92	621.337
lipid IIPubChem	0.915	1347.63
uridine diphosphatePubChem	0.912	404.161
deuteriumPubChem	0.9	2.01588
polyuridylic acidPubChem	0.9	324.181
protiumPubChem	0.9	2.01576
H(+)PubChem	0.9	2.01588
C04427PubChem	0.9	621.337
C01289PubChem	0.9	1130.45
decaprenyl phosphatePubChem	0.725	779.165