Rv3029c

Tuberculist information
Gene namefixA
Protein functionProbable electron transfer flavoprotein (beta-subunit) FixA (beta-ETF) (electron transfer flavoprotein small subunit) (ETFSS)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3388.07
Molecular mass(da)28080.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 266
	  		  	1    MTNIVVLIKQVPDTWSERKLTDGDFTLDREAADAVLDEINERAVEEALQIREKEAADGIE   60
			  	61   GSVTVLTAGPERATEAIRKALSMGADKAVHLKDDGMHGSDVIQTGWALARALGTIEGTEL  120
			  	121  VIAGNESTDGVGGAVPAIIAEYLGLPQLTHLRKVSIEGGKITGERETDEGVFTLEATLPA  180
			  	181  VISVNEKINEPRFPSFKGIMAAKKKEVTVLTLAEIGVESDEVGLANAGSTVLASTPKPAK  240
			  	241  TAGEKVTDEGEGGNQIVQYLVAQKII

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 24 to 191  |  Coverage: 62% ETF Range: 4 to 246  |  Coverage: 90% 1 Range: 2 to 266  |  Coverage: 99% 1
Number of amino acids : 266
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ETFPF0101224-191
Mtb Structural Proteome models
Model Number1
Model nameRv3029c
Template1EFV    BPDBCREDO
Template coverage6_239
Template Identity(%)32.5
Model coverage(%)91.0
Normalized DOPE score-0.434

Structure Models from Chopin
Model Number1
Profilec.26.2.3 - 3.40.50.620
Click for model details
zscore31.76
Residue begin2
Residue end266
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3029cGene nameConfidence Score
Rv3028cfixB0.999
Rv3028cfixB0.999
Rv3274cfadE250.941
Rv3274cfadE250.941
Rv0408pta0.941
Rv0408pta0.941
Rv0408pta0.941
Rv3274cfadE250.941
Rv0338cRv0338c0.909
Rv0338cRv0338c0.909
Rv1346mbtN0.904
Rv1346mbtN0.904
Rv1346mbtN0.904
Rv0632cechA30.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
flavin adenine dinucleotidePubChem0.982785.55
adenosine monophosphatePubChem0.972347.221
1,5-dihydro-FADPubChem0.9787.566