Rv2920c

Tuberculist information
Gene nameamt
Protein functionProbable ammonium-transport integral membrane protein Amt
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)3231.07
Molecular mass(da)49209.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 477
	  		  	1    VDQFPIMGVPDGGDTAWMLVSSALVLLMTPGLAFFYGGMVRSKSVLNMIMMSISAMGVVT   60
			  	61   VLWALYGYSIAFGDDVGNIAGNPSQYWGLKGLIGVNAVAADPSTQTAAVNIPLAGTLPAT  120
			  	121  VFVAFQLMFAIITVALISGAVADRLKFGAWLLFAGLWATFVYFPVAHWVFAFDGFAAEHG  180
			  	181  GWIANKLHAIDFAGGTAVHINAGVAALMLAIVLGKRRGWPATLFRPHNLPFVMLGAALLW  240
			  	241  FGWYGFNAGSATTANGVAGATFVTTTIATAAAMLGWLLTERVRDGKATTLGAASGIVAGL  300
			  	301  VAITPSCSSVNVLGALAVGVSAGVLCALAVGLKFKLGFDDSLDVVGVHLVGGLVGTLLVG  360
			  	361  LLAAPEAPAINGVAGVSKGLFYGGGFAQLERQALGACSVLVYSGIITLILALILKFTIGL  420
			  	421  RLDAEQESTGIDEAEHAESGYDFAVASGSVLPPRVTVEDSRNGIQERIGQKVEAEPK

Known structures in the PDB
No Known structures
1 48 95 142 189 236 283 330 377 424 471 Range: 16 to 441  |  Coverage: 89% Ammonium_transp Range: 13 to 441  |  Coverage: 89% 1 Range: to   |  Coverage: 0% 1
Number of amino acids : 477
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ammonium_transpPF0090916-441
Mtb Structural Proteome models
Model Number1
Model nameRv2920c
Template2B2H    APDBCREDO
Template coverage4_390
Template Identity(%)45.5
Model coverage(%)89.7
Normalized DOPE score-0.514

Structure Models from Chopin
Model Number1
Profilef.44.1.1 - 1.10.3430.10
Click for model details
zscore34.47
Residue begin
Residue end
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2920cGene nameConfidence Score
Rv2919cglnB0.999
Rv2220glnA10.941
Rv2220glnA10.941
Rv2918cglnD0.932
Rv2918cglnD0.932
Rv2918cglnD0.932
Rv2222cglnA20.925
Rv2222cglnA20.925
Rv3859cgltB0.905
Rv3859cgltB0.905
Rv3859cgltB0.905
Rv3859cgltB0.905
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
ammoniaPubChem0.99317.0305
methylaminePubChem0.93231.0571
H(+)PubChem0.92.01588
deuteriumPubChem0.92.01588
protiumPubChem0.92.01576
alpha-ketoglutaratePubChem0.859146.098
acetatePubChem0.78559.044
adenosine diphosphatePubChem0.708427.201