Rv2919c

Tuberculist information
Gene nameglnB
Protein functionProbable nitrogen regulatory protein P-II GlnB
Functional category(tuberculist)regulatory proteins
Gene location(kb)3230.74
Molecular mass(da)12227
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 112
	  		  	1    MKLITAIVKPFTLDDVKTSLEDAGVLGMTVSEIQGYGRQKGHTEVYRGAEYSVDFVPKVR   60
			  	61   IEVVVDDSIVDKVVDSIVRAARTGKIGDGKVWVSPVDTIVRVRTGERGHDAL

Known structures in the PDB
PDB ID3BZQ
Total residue count114
Number of chains1
MethodX-RAY
Resolution1.4
PDB ID3LF0
Total residue count342
Number of chains3
MethodX-RAY
Resolution2.4
1 12 23 34 45 56 67 78 89 100 111 Range: 4 to 105  |  Coverage: 90% P-II Range: to 1  |  Coverage: 0% 1 Range: 1 to 112  |  Coverage: 99% 2 Range: 1 to 112  |  Coverage: 99% 1
Number of amino acids : 112
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
P-IIPF005434-105
Mtb Structural Proteome models
Model Number1
Model nameRv2919c_3bzq_A
Template3BZQ    APDBCREDO
Template coverage0_112
Template Identity(%)100.0
Model coverage(%)99.1
Normalized DOPE score-1.578

Model Number2
Model nameRv2919c
Template2PII    APDBCREDO
Template coverage1_112
Template Identity(%)61.6
Model coverage(%)98.2
Normalized DOPE score-0.597

Structure Models from Chopin
Model Number1
Profile3.30.70.120
Click for model details
zscore17.81
Residue begin1
Residue end112
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2919cGene nameConfidence Score
Rv2920camt0.999
Rv2918cglnD0.998
Rv2918cglnD0.998
Rv2918cglnD0.998
Rv2220glnA10.98
Rv2220glnA10.98
Rv2222cglnA20.947
Rv2222cglnA20.947
Rv2221cglnE0.937
Rv2221cglnE0.937
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
adenosine triphosphatePubChem0.984507.181
alpha-ketoglutaratePubChem0.973146.098
N-acetylglutamatePubChem0.905189.166
ammoniaPubChem0.85917.0305
magnesiumPubChem0.82924.305
sulfatePubChem0.81796.0626
adenosine diphosphatePubChem0.804427.201
hydron sulfatePubChem0.8196.157
chloridePubChem0.79435.453
Na(+)PubChem0.7522.9898
phosphatePubChem0.74496.9872
2-OGPubChem0.721356.54
nitratePubChem0.7262.0049
hydron diphosphatePubChem0.713391.981
glycerolPubChem0.7192.0938
nickelPubChem0.7158.6934