Rv2603c

Tuberculist information
Gene nameRv2603c
Protein functionHighly conserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2930.8
Molecular mass(da)26798.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 251
	  		  	1    MSGHSKWATTKHKKAVVDARRGKMFARLIKNIEVAARVGGGDPAGNPTLYDAIQKAKKSS   60
			  	61   VPNENIERARKRGAGEEAGGADWQTIMYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTR  120
			  	121  NGGTMADPGSVSYLFSRKGVVTLEKNGLTEDDVLAAVLEAGAEDVNDLGDSFEVISEPAE  180
			  	181  LVAVRSALQDAGIDYESAEASFQPSVSVPVDLDGARKVFKLVDALEDSDDVQNVWTNVDV  240
			  	241  SDEVLAALDDE

Known structures in the PDB
No Known structures
1 26 51 76 101 126 151 176 201 226 251 Range: 5 to 239  |  Coverage: 93% Transcrip_reg Range: 3 to 248  |  Coverage: 97% 1 Range: 3 to 248  |  Coverage: 97% 1
Number of amino acids : 251
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Transcrip_regPF017095-239
Mtb Structural Proteome models
Model Number1
Model nameRv2603c
Template1KON    APDBCREDO
Template coverage3_246
Template Identity(%)48.1
Model coverage(%)97.6
Normalized DOPE score-0.479

Structure Models from Chopin
Model Number1
Profilee.39.1.1
Click for model details
zscore48.88
Residue begin3
Residue end248
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2603cGene nameConfidence Score
Rv2604csnoP0.973
Rv2606csnzP0.971
Rv2594cruvC0.924
Rv2605ctesB20.921
Rv2572caspS0.907
Rv2572caspS0.907
Rv2572caspS0.907
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
selenomethioninePubChem0.708196.106
SeMetPubChem0.708196.106