Rv2604c

Tuberculist information
Gene namesnoP
Protein functionProbable glutamine amidotransferase SnoP
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)2931.69
Molecular mass(da)21040.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 198
	  		  	1    VSVPRVGVLALQGDTREHLAALRECGAEPMTVRRRDELDAVDALVIPGGESTTMSHLLLD   60
			  	61   LDLLGPLRARLADGLPAYGSCAGMILLASEILDAGAAGRQALPLRAMNMTVRRNAFGSQV  120
			  	121  DSFEGDIEFAGLDDPVRAVFIRAPWVERVGDGVQVLARAAGHIVAVRQGAVLATAFHPEM  180
			  	181  TGDRRIHQLFVDIVTSAA

Known structures in the PDB
No Known structures
1 20 39 58 77 96 115 134 153 172 191 Range: 8 to 196  |  Coverage: 94% SNO Range: 2 to 197  |  Coverage: 98% 1 Range: 1 to 198  |  Coverage: 99% 1
Number of amino acids : 198
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
SNOPF011748-196
Mtb Structural Proteome models
Model Number1
Model nameRv2604c
Template1Q7R    APDBCREDO
Template coverage-1_189
Template Identity(%)47.1
Model coverage(%)98.5
Normalized DOPE score-1.206

Structure Models from Chopin
Model Number1
Profilec.23.16.1 - 3.40.50.880
Click for model details
zscore15.51
Residue begin1
Residue end198
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2604cGene nameConfidence Score
Rv2606csnzP0.999
Rv2607pdxH0.981
Rv2607pdxH0.981
Rv2603cRv2603c0.973
Rv2605ctesB20.934
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
ribulose 5-phosphatePubChem0.987230.11
pyridoxal phosphatePubChem0.972247.142
ribulose-5-phosphatePubChem0.969230.11
D-glyceraldehyde-3-phosphatePubChem0.943170.058
vitamin B6PubChem0.806169.178
phosphatePubChem0.75896.9872
hydron diphosphatePubChem0.706391.981
selenomethioninePubChem0.7196.106
chloridePubChem0.735.453
polyglutaminePubChem0.7146.145
SeMetPubChem0.7196.106
polyethylene glycolPubChem0.762.0678
ethylene glycol; hydronPubChem0.763.0758