Rv1853

Tuberculist information
Gene nameureD
Protein functionProbable urease accessory protein UreD
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)2101.02
Molecular mass(da)22303.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 208
	  		  	1    VVASPNRLPRIDCRGGVQARRTAPDTVHLVSAAATPLGGDTMRIRVIVERGAQLRLRSAA   60
			  	61   ATVALPGVDTLTSHAHWEIDVTGTLDVDLEPTVVAASARHLSHATLRLHDDGRVRLRERV  120
			  	121  QIGRCNEREGFWSSSLQADRHGRPLLRHRVELGAGSLADDVIAAPRATISELRYPATAFT  180
			  	181  DAIDARSTVLALAGGGTLSTWQADRLPG

Known structures in the PDB
No Known structures
1 21 41 61 81 101 121 141 161 181 201 Range: 26 to 178  |  Coverage: 73% UreD
Number of amino acids : 208
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UreDPF0177426-178
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1853Gene nameConfidence Score
Rv1851ureF0.997
Rv1852ureG0.989
Rv1848ureA0.987
Rv1849ureB0.979
Rv1850ureC0.979
Rv1850ureC0.979
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
urea solutionPubChem0.960.0553
ammoniaPubChem0.917.0305
hydroxyl radicalsPubChem0.917.0073
carbon dioxidePubChem0.944.0095