Rv1851

Tuberculist information
Gene nameureF
Protein functionUrease accessory protein UreF
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)2099.69
Molecular mass(da)22355.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 211
	  		  	1    MTSLAVLLTLADSRLPTGAHVHSGGIEEAIAAGMVTGLATLEAFLKRRVRTHGLLTASIA   60
			  	61   AAVHRGELAVDDADRETDARTPAPAARHASRSQGRGLIRLARRVWPDSGWEELGPRPHLA  120
			  	121  VVAGRVGALSGLAPEHNALHLVYITMTGSAIAAQRLLALDPAEVTVVTFQLSELCEQIAQ  180
			  	181  EATAGLADLSDPLLDTLAQRHDERVRPLFVS

Known structures in the PDB
No Known structures
1 22 43 64 85 106 127 148 169 190 211 Range: 37 to 174  |  Coverage: 64% UreF
Number of amino acids : 211
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UreFPF0173037-174
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1851Gene nameConfidence Score
Rv1848ureA0.999
Rv1849ureB0.999
Rv1850ureC0.999
Rv1850ureC0.999
Rv1852ureG0.999
Rv1853ureD0.997
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
carbon dioxidePubChem0.90544.0095
ammoniaPubChem0.90417.0305
urea solutionPubChem0.960.0553
hydroxyl radicalsPubChem0.917.0073