Rv1710

Tuberculist information
Gene namescpB
Protein functionPossible segregation and condensation protein ScpB
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1938.15
Molecular mass(da)25244.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 231
	  		  	1    VTEHMPEHDPSYGIPDIAEPAELDADELKRVLEALLLVIDTPVTADALAAATEQPVYRVA   60
			  	61   AKLQLMADELTGRDSGIDLRHTSEGWRMYTRARFAPYVEKLLLDGARTKLTRAALETLAV  120
			  	121  VAYRQPVTRARVSAVRGVNVDAVMRTLLARGLITEVGTDADTGAVTFATTELFLERLGLT  180
			  	181  SLSELPDIAPLLPDVDTIDDLSESLDSEPRFIKLTGELASEQTLSFDVDRD

Known structures in the PDB
PDB ID2Z99
Total residue count219
Number of chains1
MethodX-RAY
Resolution2.3
1 24 47 70 93 116 139 162 185 208 231 Range: 30 to 188  |  Coverage: 68% DUF387 Range: 21 to 180  |  Coverage: 68% 1 Range: 22 to 179  |  Coverage: 67% 2 Range: 18 to 103  |  Coverage: 36% 1 Range: 97 to 187  |  Coverage: 38% 2 Range: 21 to 201  |  Coverage: 77% 3
Number of amino acids : 231
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF387PF0407930-188
Mtb Structural Proteome models
Model Number1
Model nameRv1710_2z99_A
Template2Z99    APDBCREDO
Template coverage21_180
Template Identity(%)100.0
Model coverage(%)68.8
Normalized DOPE score-0.335

Model Number2
Model nameRv1710
Template1T6S    APDBCREDO
Template coverage2_162
Template Identity(%)31.0
Model coverage(%)68.0
Normalized DOPE score0.203

Structure Models from Chopin
Model Number1
Profilea.4.5.60
Click for model details
zscore13.61
Residue begin18
Residue end103
Model Number2
Profilea.4.5.9 - 1.10.10.10
Click for model details
zscore5.25
Residue begin97
Residue end187
Model Number3
Profilea.4.5.1, d.94.2.1 - 1.10.10.10, 3.30.1340.20
Click for model details
zscore5.17
Residue begin21
Residue end201
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1710Gene nameConfidence Score
Rv1709scpA0.999
Rv1711Rv17110.985
Rv1711Rv17110.985
Rv1712cmk0.97
Rv1713engA0.97
Rv1713engA0.97
Rv2922csmc0.961
Rv2922csmc0.961
Rv2725chflX0.92
Rv2725chflX0.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions