Rv1463

Tuberculist information
Gene nameRv1463
Protein functionProbable conserved ATP-binding protein ABC transporter
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1650.72
Molecular mass(da)28822.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 266
	  		  	1    MTILEIKDLHVSVENPAEADHEIPILRGVDLTVKSGETHALMGPNGSGKSTLSYAIAGHP   60
			  	61   KYHVTSGTITLDGADVLAMSIDERARAGLFLAMQYPVEVPGVSMSNFLRSAATAIRGEPP  120
			  	121  KLRHWVKEVKAAMAALDIDPAFAERSVNEGFSGGEKKRHEILQLELLKPKIAILDETDSG  180
			  	181  LDVDALRVVSEGVNRYAESQHGGILLITHYTRILRYIHPEYVHVFVGGRIVESGGSELAD  240
			  	241  ELDQNGYVRFSPASGRYPHQPAPTGA

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 26 to 179  |  Coverage: 57% ABC_tran Range: 4 to 247  |  Coverage: 91% 1 Range: 1 to 266  |  Coverage: 99% 1
Number of amino acids : 266
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ABC_tranPF0000526-179
Mtb Structural Proteome models
Model Number1
Model nameRv1463
Template2D2E    APDBCREDO
Template coverage4_239
Template Identity(%)56.3
Model coverage(%)91.4
Normalized DOPE score-0.859

Structure Models from Chopin
Model Number1
Profilec.37.1.12
Click for model details
zscore25.57
Residue begin1
Residue end266
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1463Gene nameConfidence Score
Rv1461Rv14610.999
Rv1461Rv14610.999
Rv1462Rv14620.999
Rv1464csd0.999
Rv1465Rv14650.995
Rv1466Rv14660.992
Rv1460Rv14600.988
Rv2204cRv2204c0.95
Rv3025ciscS0.919
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions