Rv1462

Tuberculist information
Gene nameRv1462
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)1649.53
Molecular mass(da)42522.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 397
	  		  	1    MTAPGLTAAVEGIAHNKGELFASFDVDAFEVPHGRDEIWRFTPLRRLRGLHDGSARATGS   60
			  	61   ATITVSERPGVYTQTVRRGDPRLGEGGVPTDRVAAQAFSSFNSATLVTVERDTQVVEPVG  120
			  	121  ITVTGPGEGAVAYGHLQVRIEELGEAVVVIDHRGGGTYADNVEFVVDDAARLTAVWIADW  180
			  	181  ADNTVHLSAHHARIGKDAVLRHVTVMLGGDVVRMSAGVRFCGAGGDAELLGLYFADDGQH  240
			  	241  LESRLLVDHAHPDCKSNVLYKGALQGDPASSLPDAHTVWVGDVLIRAQATGTDTFEVNRN  300
			  	301  LVLTDGARADSVPNLEIETGEIVGAGHASATGRFDDEQLFYLRSRGIPEAQARRLVVRGF  360
			  	361  FGEIIAKIAVPEVRERLTAAIEHELEITESTEKTTVS

Known structures in the PDB
No Known structures
1 40 79 118 157 196 235 274 313 352 391 Range: 127 to 360  |  Coverage: 58% UPF0051 Range: 31 to 385  |  Coverage: 89% 1 Range: 1 to 388  |  Coverage: 97% 1
Number of amino acids : 397
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UPF0051PF01458127-360
Mtb Structural Proteome models
Model Number1
Model nameRv1462
Template1VH4    APDBCREDO
Template coverage41_418
Template Identity(%)26.2
Model coverage(%)89.2
Normalized DOPE score0.032

Structure Models from Chopin
Model Number1
Profileb.80.6.1
Click for model details
zscore55.43
Residue begin1
Residue end388
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1462Gene nameConfidence Score
Rv1463Rv14630.999
Rv1464csd0.997
Rv1466Rv14660.996
Rv1465Rv14650.995
Rv1461Rv14610.994
Rv1461Rv14610.994
Rv1460Rv14600.975
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions