Rv0638

Tuberculist information
Gene namesecE1
Protein functionProbable preprotein translocase SecE1
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)733.737
Molecular mass(da)16924.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 161
	  		  	1    VSDEGDVADEAVADGAENADSRGSGGRTALVTKPVVRPQRPTGKRSRSRAAGADADVDVE   60
			  	61   EPSTAASEATGVAKDDSTTKAVSKAARAKKASKPKARSVNPIAFVYNYLKQVVAEMRKVI  120
			  	121  WPNRKQMLTYTSVVLAFLAFMVALVAGADLGLTKLVMLVFG

Known structures in the PDB
PDB ID3ONR
Total residue count864
Number of chains12
MethodX-RAY
Resolution1.8
1 17 33 49 65 81 97 113 129 145 161 Range: 104 to 160  |  Coverage: 34% SecE Range: 112 to 157  |  Coverage: 27% 1
Number of amino acids : 161
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
SecEPF00584104-160
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
Model Number1
Profile1.20.5.1030
Click for model details
zscore8.2
Residue begin112
Residue end157
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0638Gene nameConfidence Score
Rv0732secY0.992
Rv1440secG0.983
Rv2586csecF0.982
Rv2586csecF0.982
Rv2587csecD0.982
Rv2587csecD0.982
Rv0639nusG0.965
Rv0639nusG0.965
Rv1821secA20.937
Rv1821secA20.937
Rv1821secA20.937
Rv3240csecA10.923
Rv3240csecA10.923
Rv3240csecA10.923
Rv3846sodA0.905
Rv3846sodA0.905
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions