SInCRe - Rv0015c

Tuberculist information

Gene name	pknA
Protein function	Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A)
Functional category(tuberculist)	regulatory proteins
Gene location(kb)	17.467
Molecular mass(da)	45597
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 431

	  		  	1    MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRA   60
			  	61   EARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALD  120
			  	121  MLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGT  180
			  	181  AQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPD  240
			  	241  LPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPSQTPPPGRAAPAAIPSG  300
			  	301  TTARVAANSAGRTAASRRSRPATGGHRPPRRTFSSGQRALLWAAGVLGALAIIIAVLLVI  360
			  	361  KAPGDNSPQQAPTPTVTTTGNPPASNTGGTDASPRLNWTERGETRHSGLQSWVVPPTPHS  420
			  	421  RASLARYEIAQ

Known structures in the PDB

No Known structures

Number of amino acids : 431

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
Pkinase	PF00069	13-270

Mtb Structural Proteome models

Model Number	1
Model name	Rv0015c
Template	1O6Y APDB CREDO
Template coverage	7_279
Template Identity(%)	42.4
Model coverage(%)	62.2
Normalized DOPE score	-0.796

Model Number	2
Model name	Rv0015c.1
Template	1KOB APDB CREDO
Template coverage	42_375
Template Identity(%)	20.4
Model coverage(%)	78.7
Normalized DOPE score	-0.012

Structure Models from Chopin

Model Number	1
Profile	d.144.1.7 Click for model details
zscore	20.63
Residue begin	1
Residue end	431

Binding pockets

STRING

Cytoscape Web will replace the contents of this div with protein-protein interaction network.

Protein interacting with Rv0015c	Gene name	Confidence Score
Rv0018c	pstP	0.997
Rv0016c	pbpA	0.979
Rv0017c	rodA	0.978
Rv2150c	ftsZ	0.968
Rv2150c	ftsZ	0.968
Rv2145c	wag31	0.966
Rv0014c	pknB	0.908
Rv0014c	pknB	0.908

Potential ligand/drug binding sites

Protein Model	Pocket Number	Drug Binding Site	PMIN Score	Pvalue PMIN	PMAX Score	Pvalue PMAX
Rv0015c.1	9	3bbt_FMM_D_91 PDB CREDO	0.710	0.073	0.710	0.000
Rv0015c.1	9	1mx1_THA_C_3 PDB CREDO	0.706	0.077	0.658	0.001
Rv0015c.1	9	1mx1_THA_E_5 PDB CREDO	0.736	0.056	0.639	0.001
Rv0015c.1	10	3qt0_486_A_4 PDB CREDO	0.655	0.119	0.633	0.001
Rv0015c.1	27	3r9c_ECL_A_452 PDB CREDO	0.631	0.144	0.631	0.001
Rv0015c.1	27	3q1e_T44_D_328 PDB CREDO	0.656	0.119	0.629	0.001
Rv0015c.1	27	2xn5_FUN_A_1356 PDB CREDO	0.682	0.095	0.628	0.001
Rv0015c.1	9	1ya4_CTX_B_2 PDB CREDO	0.842	0.012	0.627	0.001
Rv0015c.1	9	1ya4_CTX_C_3 PDB CREDO	0.835	0.014	0.622	0.001
Rv0015c.1	9	3erd_DES_B_800 PDB CREDO	0.692	0.087	0.622	0.001
Rv0015c.1	27	1ict_T44_C_128 PDB CREDO	0.645	0.129	0.619	0.001
Rv0015c.1	27	1ict_T44_D_129 PDB CREDO	0.699	0.081	0.619	0.001
Rv0015c.1	9	3spk_TPV_A_100 PDB CREDO	0.635	0.139	0.614	0.002
Rv0015c.1	9	1jg2_ADN_A_500 PDB CREDO	0.630	0.145	0.609	0.002
Rv0015c.1	9	3ri5_IVM_C_350 PDB CREDO	0.677	0.100	0.609	0.002
Rv0015c.1	9	3rif_IVM_A_402 PDB CREDO	0.676	0.100	0.608	0.002
Rv0015c.1	9	3rif_IVM_A_403 PDB CREDO	0.675	0.101	0.608	0.002
Rv0015c.1	10	2h77_T3_A_1 PDB CREDO	0.650	0.124	0.607	0.002
Rv0015c.1	9	3rif_IVM_D_402 PDB CREDO	0.675	0.102	0.607	0.002
Rv0015c.1	10	1bsx_T3_A_1 PDB CREDO	0.694	0.085	0.607	0.002
Rv0015c.1	4	1uay_ADN_A_1001 PDB CREDO	0.667	0.109	0.607	0.002
Rv0015c.1	9	3rif_IVM_B_403 PDB CREDO	0.674	0.102	0.607	0.002
Rv0015c.1	10	1bsx_T3_B_2 PDB CREDO	0.694	0.086	0.607	0.002
Rv0015c.1	27	2o7o_DXT_A_222 PDB CREDO	0.659	0.116	0.607	0.002
Rv0015c.1	27	2trt_TAC_A_222 PDB CREDO	0.659	0.116	0.607	0.002
Rv0015c.1	9	3so9_017_A_100 PDB CREDO	0.759	0.043	0.605	0.002
Rv0015c.1	10	1fm6_BRL_D_503 PDB CREDO	0.627	0.149	0.605	0.002
Rv0015c.1	9	3ria_IVM_C_349 PDB CREDO	0.671	0.104	0.604	0.002
Rv0015c.1	10	1zgy_BRL_A_503 PDB CREDO	0.647	0.128	0.604	0.002
Rv0015c.1	27	2xrl_DXT_A_1211 PDB CREDO	0.628	0.147	0.602	0.002
Rv0015c.1	10	2xkw_P1B_B_1475 PDB CREDO	0.641	0.134	0.597	0.002
Rv0015c.1	10	3gws_T3_X_500 PDB CREDO	0.680	0.097	0.594	0.002
Rv0015c.1	10	3uvv_T3_A_501 PDB CREDO	0.700	0.081	0.592	0.002
Rv0015c.1	9	3bbt_FMM_B_91 PDB CREDO	0.734	0.057	0.591	0.002
Rv0015c.1	4	3ug2_IRE_A_1 PDB CREDO	0.621	0.155	0.591	0.002
Rv0015c.1	27	3ads_IMN_B_3 PDB CREDO	0.616	0.160	0.590	0.003
Rv0015c.1	9	1nhz_486_A_800 PDB CREDO	0.611	0.166	0.590	0.003
Rv0015c.1	9	1s9p_DES_D_600 PDB CREDO	0.632	0.143	0.590	0.003
Rv0015c.1	10	2h79_T3_A_1 PDB CREDO	0.653	0.122	0.590	0.003
Rv0015c.1	9	3oht_1N1_B_1000 PDB CREDO	0.632	0.143	0.589	0.003
Rv0015c.1	27	3f4x_KLT_A_300 PDB CREDO	0.717	0.068	0.587	0.003
Rv0015c.1	9	3h52_486_A_3 PDB CREDO	0.736	0.056	0.587	0.003
Rv0015c.1	10	1xzx_T3_X_500 PDB CREDO	0.693	0.086	0.587	0.003
Rv0015c.1	10	2prg_BRL_A_1 PDB CREDO	0.605	0.173	0.584	0.003
Rv0015c.1	27	1ie4_T44_A_128 PDB CREDO	0.609	0.168	0.584	0.003
Rv0015c.1	14	1s9p_DES_D_600 PDB CREDO	0.626	0.149	0.584	0.003
Rv0015c.1	9	1s9p_DES_A_459 PDB CREDO	0.624	0.151	0.582	0.003
Rv0015c.1	14	1qkn_RAL_A_600 PDB CREDO	0.642	0.132	0.581	0.003
Rv0015c.1	10	3bbt_FMM_D_91 PDB CREDO	0.601	0.177	0.581	0.003
Rv0015c.1	9	3erd_DES_A_600 PDB CREDO	0.642	0.133	0.577	0.003
Rv0015c.1	14	3qt0_486_A_4 PDB CREDO	0.577	0.207	0.577	0.003
Rv0015c.1	9	2jfa_RAL_B_600 PDB CREDO	0.700	0.081	0.576	0.003
Rv0015c.1	9	1ya3_STR_A_1001 PDB CREDO	0.595	0.185	0.575	0.003
Rv0015c.1	14	2h77_T3_A_1 PDB CREDO	0.593	0.188	0.573	0.003
Rv0015c.1	27	3cs8_BRL_A_503 PDB CREDO	0.647	0.127	0.573	0.003
Rv0015c.1	27	1ie4_T44_B_328 PDB CREDO	0.673	0.103	0.572	0.003
Rv0015c.1	9	2h42_VIA_A_901 PDB CREDO	0.572	0.214	0.572	0.003
Rv0015c.1	9	1a28_STR_B_2 PDB CREDO	0.652	0.123	0.571	0.004
Rv0015c.1	10	3jwq_VIA_D_901 PDB CREDO	0.590	0.191	0.570	0.004
Rv0015c.1	10	3ln1_CEL_D_682 PDB CREDO	0.590	0.191	0.570	0.004
Rv0015c.1	27	3q1e_T44_C_128 PDB CREDO	0.697	0.083	0.570	0.004
Rv0015c.1	9	3h52_486_B_1 PDB CREDO	0.736	0.056	0.570	0.004
Rv0015c.1	7	3ret_SAL_B_201 PDB CREDO	0.637	0.138	0.569	0.004
Rv0015c.1	9	3h52_486_D_2 PDB CREDO	0.712	0.072	0.568	0.004
Rv0015c.1	9	2q1v_PDN_A_248 PDB CREDO	0.588	0.194	0.568	0.004
Rv0015c.1	10	3h0a_9RA_A_500 PDB CREDO	0.588	0.194	0.568	0.004
Rv0015c.1	9	2aoh_FRD_C_305 PDB CREDO	0.733	0.058	0.568	0.004
Rv0015c.1	4	4dta_ADN_A_401 PDB CREDO	0.652	0.123	0.567	0.004
Rv0015c.1	9	1err_RAL_A_600 PDB CREDO	0.688	0.090	0.566	0.004
Rv0015c.1	9	2jfa_RAL_A_600 PDB CREDO	0.667	0.108	0.566	0.004
Rv0015c.1	9	1err_RAL_B_600 PDB CREDO	0.688	0.090	0.566	0.004
Rv0015c.1	14	3gws_T3_X_500 PDB CREDO	0.625	0.151	0.565	0.004
Rv0015c.1	10	1s9p_DES_A_459 PDB CREDO	0.585	0.197	0.565	0.004
Rv0015c.1	14	3ln1_CEL_D_682 PDB CREDO	0.565	0.224	0.565	0.004
Rv0015c.1	14	3oct_1N1_A_663 PDB CREDO	0.584	0.198	0.565	0.004
Rv0015c.1	4	2uxp_CLM_B_1211 PDB CREDO	0.620	0.156	0.564	0.004
Rv0015c.1	4	3s20_CER_B_1 PDB CREDO	0.564	0.224	0.564	0.004
Rv0015c.1	14	1bsx_T3_A_1 PDB CREDO	0.624	0.152	0.564	0.004
Rv0015c.1	14	1bsx_T3_B_2 PDB CREDO	0.624	0.152	0.564	0.004
Rv0015c.1	9	1ya3_STR_B_2001 PDB CREDO	0.583	0.200	0.563	0.004
Rv0015c.1	14	3erd_DES_A_600 PDB CREDO	0.626	0.149	0.563	0.004
Rv0015c.1	27	2xn7_T44_A_1355 PDB CREDO	0.612	0.165	0.563	0.004
Rv0015c.1	27	2xn6_T44_A_1370 PDB CREDO	0.611	0.166	0.562	0.004
Rv0015c.1	27	2riw_T44_A_1395 PDB CREDO	0.562	0.227	0.562	0.004
Rv0015c.1	7	3jw3_TOP_A_208 PDB CREDO	0.595	0.185	0.562	0.004
Rv0015c.1	14	1s9p_DES_A_459 PDB CREDO	0.602	0.176	0.562	0.004
Rv0015c.1	9	1n49_RIT_D_401 PDB CREDO	0.793	0.028	0.561	0.004
Rv0015c.1	21	3oct_1N1_A_663 PDB CREDO	0.561	0.229	0.561	0.004
Rv0015c.1	27	2vke_TAC_A_222 PDB CREDO	0.659	0.116	0.560	0.004
Rv0015c.1	10	3cs8_BRL_A_503 PDB CREDO	0.726	0.062	0.560	0.004
Rv0015c.1	10	3oht_1N1_B_1000 PDB CREDO	0.580	0.204	0.560	0.004
Rv0015c.1	9	2aa6_STR_A_401 PDB CREDO	0.599	0.180	0.560	0.004
Rv0015c.1	4	3rf4_FUN_A_201 PDB CREDO	0.618	0.158	0.560	0.004
Rv0015c.1	9	3spk_TPV_B_100 PDB CREDO	0.767	0.039	0.560	0.004
Rv0015c.1	7	1yi4_ADN_A_306 PDB CREDO	0.661	0.114	0.559	0.004
Rv0015c.1	9	2aax_PDN_B_503 PDB CREDO	0.598	0.182	0.559	0.004
Rv0015c.1	27	2xpw_OTC_A_222 PDB CREDO	0.657	0.118	0.559	0.004
Rv0015c.1	10	2hw2_RFP_A_1200 PDB CREDO	0.681	0.096	0.559	0.004
Rv0015c.1	14	2fum_MIX_D_3539 PDB CREDO	0.558	0.233	0.558	0.004
Rv0015c.1	4	3rf4_FUN_C_203 PDB CREDO	0.615	0.161	0.557	0.004
Rv0015c.1	9	2aax_PDN_A_502 PDB CREDO	0.596	0.184	0.557	0.004
Rv0015c.1	21	2xkw_P1B_B_1475 PDB CREDO	0.598	0.181	0.557	0.004
Rv0015c.1	14	1zgy_BRL_A_503 PDB CREDO	0.576	0.209	0.557	0.004
Rv0015c.1	4	3rem_SAL_A_301 PDB CREDO	0.614	0.163	0.556	0.005
Rv0015c.1	7	3jw3_TOP_B_208 PDB CREDO	0.590	0.191	0.556	0.005
Rv0015c.1	9	2aa6_STR_B_402 PDB CREDO	0.594	0.186	0.556	0.005
Rv0015c.1	7	3hgx_SAL_B_104 PDB CREDO	0.622	0.154	0.556	0.005
Rv0015c.1	10	3e22_LOC_B_700 PDB CREDO	0.676	0.101	0.554	0.005
Rv0015c.1	10	2h42_VIA_A_901 PDB CREDO	0.574	0.212	0.554	0.005
Rv0015c.1	4	3ilt_TRU_E_800 PDB CREDO	0.582	0.202	0.554	0.005
Rv0015c.1	4	3rf4_FUN_B_202 PDB CREDO	0.612	0.165	0.554	0.005
Rv0015c.1	4	3ads_IMN_B_3 PDB CREDO	0.695	0.085	0.553	0.005
Rv0015c.1	14	2h79_T3_A_1 PDB CREDO	0.591	0.190	0.552	0.005
Rv0015c.1	9	3h0a_9RA_A_500 PDB CREDO	0.552	0.241	0.552	0.005
Rv0015c.1	14	1klm_SPP_A_999 PDB CREDO	0.660	0.114	0.552	0.005
Rv0015c.1	10	3e22_LOC_D_700 PDB CREDO	0.673	0.103	0.552	0.005
Rv0015c.1	10	1fm6_BRL_X_504 PDB CREDO	0.652	0.122	0.552	0.005
Rv0015c.1	14	1xzx_T3_X_500 PDB CREDO	0.629	0.146	0.551	0.005
Rv0015c.1	14	1fm6_BRL_D_503 PDB CREDO	0.591	0.190	0.551	0.005
Rv0015c.1	21	1fm6_BRL_D_503 PDB CREDO	0.571	0.216	0.551	0.005
Rv0015c.1	27	2x7h_PFN_A_1372 PDB CREDO	0.688	0.090	0.551	0.005
Rv0015c.1	9	1qkn_RAL_A_600 PDB CREDO	0.608	0.169	0.551	0.005
Rv0015c.1	6	1xkk_FMM_A_91 PDB CREDO	0.669	0.107	0.549	0.005
Rv0015c.1	4	2eva_ADN_A_498 PDB CREDO	0.577	0.208	0.549	0.005
Rv0015c.1	21	2cbr_A80_A_201 PDB CREDO	0.635	0.140	0.549	0.005
Rv0015c.1	9	1jg3_ADN_A_500 PDB CREDO	0.632	0.142	0.549	0.005
Rv0015c.1	9	1mx1_THA_D_4 PDB CREDO	0.736	0.056	0.549	0.005
Rv0015c.1	9	3ria_IVM_E_349 PDB CREDO	0.680	0.097	0.548	0.005
Rv0015c.1	14	2cbr_A80_A_201 PDB CREDO	0.654	0.120	0.547	0.005
Rv0015c.1	27	2uxo_TAC_B_1211 PDB CREDO	0.594	0.186	0.547	0.005
Rv0015c.1	21	2prg_BRL_A_1 PDB CREDO	0.566	0.222	0.547	0.005
Rv0015c.1	4	2uxp_CLM_A_1211 PDB CREDO	0.600	0.178	0.547	0.005
Rv0015c.1	9	1mx1_THA_F_6 PDB CREDO	0.733	0.058	0.546	0.005
Rv0015c.1	9	3ri5_IVM_A_349 PDB CREDO	0.679	0.098	0.546	0.005
Rv0015c.1	14	3uvv_T3_A_501 PDB CREDO	0.622	0.153	0.545	0.005
Rv0015c.1	9	3ri5_IVM_B_349 PDB CREDO	0.677	0.099	0.545	0.005
Rv0015c.1	9	3ria_IVM_A_348 PDB CREDO	0.677	0.099	0.545	0.005
Rv0015c.1	4	1tz8_DES_B_128 PDB CREDO	0.704	0.078	0.545	0.005
Rv0015c.1	9	1p93_DEX_B_2999 PDB CREDO	0.545	0.251	0.545	0.005
Rv0015c.1	9	3rhw_IVM_A_348 PDB CREDO	0.676	0.100	0.545	0.005
Rv0015c.1	21	3ads_IMN_A_2 PDB CREDO	0.544	0.252	0.544	0.005
Rv0015c.1	27	2ceo_T44_A_1395 PDB CREDO	0.593	0.187	0.544	0.005
Rv0015c.1	9	3rhw_IVM_B_348 PDB CREDO	0.676	0.101	0.544	0.006
Rv0015c.1	9	3rif_IVM_E_402 PDB CREDO	0.676	0.101	0.544	0.006
Rv0015c.1	14	3h0a_9RA_A_500 PDB CREDO	0.544	0.252	0.544	0.006
Rv0015c.1	27	3adx_IMN_B_3 PDB CREDO	0.590	0.191	0.544	0.006
Rv0015c.1	9	1p93_DEX_A_1999 PDB CREDO	0.544	0.253	0.544	0.006
Rv0015c.1	9	3ri5_IVM_D_349 PDB CREDO	0.675	0.101	0.544	0.006
Rv0015c.1	9	3ria_IVM_E_348 PDB CREDO	0.675	0.101	0.544	0.006
Rv0015c.1	9	3rhw_IVM_D_349 PDB CREDO	0.674	0.102	0.543	0.006
Rv0015c.1	9	3ria_IVM_C_350 PDB CREDO	0.674	0.102	0.543	0.006
Rv0015c.1	9	3rhw_IVM_D_348 PDB CREDO	0.673	0.103	0.542	0.006
Rv0015c.1	4	1r9o_FLP_A_501 PDB CREDO	0.596	0.184	0.542	0.006
Rv0015c.1	14	2jfa_RAL_A_600 PDB CREDO	0.639	0.136	0.542	0.006
Rv0015c.1	14	3oez_STI_B_601 PDB CREDO	0.639	0.136	0.542	0.006
Rv0015c.1	27	2ceo_T44_B_1395 PDB CREDO	0.590	0.191	0.542	0.006
Rv0015c.1	4	2x7h_PFN_A_1372 PDB CREDO	0.568	0.219	0.542	0.006
Rv0015c.1	4	1sn0_T44_C_601 PDB CREDO	0.623	0.153	0.541	0.006
Rv0015c.1	9	1sqn_NDR_A_1001 PDB CREDO	0.580	0.204	0.541	0.006
Rv0015c.1	9	3rhw_IVM_B_349 PDB CREDO	0.672	0.104	0.541	0.006
Rv0015c.1	10	3jwq_VIA_B_901 PDB CREDO	0.581	0.203	0.541	0.006
Rv0015c.1	14	2prg_BRL_A_1 PDB CREDO	0.580	0.204	0.541	0.006
Rv0015c.1	14	3qgz_ADN_A_127 PDB CREDO	0.622	0.153	0.540	0.006
Rv0015c.1	14	1fm6_BRL_X_504 PDB CREDO	0.616	0.160	0.540	0.006
Rv0015c.1	14	1lw0_NVP_A_999 PDB CREDO	0.724	0.064	0.539	0.006
Rv0015c.1	9	2aoj_FRD_C_305 PDB CREDO	0.739	0.054	0.539	0.006
Rv0015c.1	10	1mx1_THA_C_3 PDB CREDO	0.558	0.233	0.539	0.006
Rv0015c.1	4	3ik6_HCZ_B_800 PDB CREDO	0.595	0.185	0.539	0.006
Rv0015c.1	27	2itz_IRE_A_2021 PDB CREDO	0.585	0.197	0.539	0.006
Rv0015c.1	14	2hyy_STI_B_600 PDB CREDO	0.696	0.084	0.539	0.006
Rv0015c.1	9	2w8y_486_A_1000 PDB CREDO	0.717	0.069	0.538	0.006
Rv0015c.1	4	2bxf_DZP_A_2001 PDB CREDO	0.591	0.190	0.538	0.006
Rv0015c.1	4	1sn0_T44_B_602 PDB CREDO	0.625	0.151	0.538	0.006
Rv0015c.1	4	3rem_SAL_B_301 PDB CREDO	0.594	0.187	0.538	0.006
Rv0015c.1	14	1gs4_ZK5_A_1918 PDB CREDO	0.597	0.183	0.537	0.006
Rv0015c.1	21	3ln1_CEL_D_682 PDB CREDO	0.556	0.236	0.537	0.006
Rv0015c.1	4	2bxf_DZP_B_2001 PDB CREDO	0.590	0.191	0.537	0.006
Rv0015c.1	9	1sqn_NDR_B_2001 PDB CREDO	0.575	0.210	0.537	0.006
Rv0015c.1	14	2gqg_1N1_A_501 PDB CREDO	0.596	0.184	0.537	0.006
Rv0015c.1	27	2xpv_MIY_A_1209 PDB CREDO	0.759	0.043	0.536	0.006
Rv0015c.1	10	1y0x_T44_X_500 PDB CREDO	0.696	0.084	0.536	0.006
Rv0015c.1	10	1gs4_ZK5_A_1918 PDB CREDO	0.575	0.210	0.536	0.006
Rv0015c.1	9	3h52_486_C_4 PDB CREDO	0.595	0.184	0.536	0.006
Rv0015c.1	14	1kij_NOV_A_400 PDB CREDO	0.535	0.265	0.535	0.006
Rv0015c.1	10	3spk_TPV_A_100 PDB CREDO	0.573	0.213	0.535	0.006
Rv0015c.1	10	1s9p_DES_D_600 PDB CREDO	0.554	0.239	0.535	0.006
Rv0015c.1	21	2prg_BRL_B_2 PDB CREDO	0.554	0.239	0.535	0.006
Rv0015c.1	21	1zgy_BRL_A_503 PDB CREDO	0.572	0.214	0.534	0.006
Rv0015c.1	6	1hwk_117_B_1 PDB CREDO	0.809	0.022	0.534	0.006
Rv0015c.1	4	1qhy_CLM_A_999 PDB CREDO	0.561	0.229	0.534	0.006
Rv0015c.1	4	3hm1_J3Z_A_2 PDB CREDO	0.587	0.195	0.534	0.006
Rv0015c.1	9	3e22_LOC_B_700 PDB CREDO	0.629	0.146	0.534	0.006
Rv0015c.1	9	3e22_LOC_D_700 PDB CREDO	0.628	0.147	0.533	0.007
Rv0015c.1	7	3hgx_SAL_A_102 PDB CREDO	0.597	0.183	0.533	0.007
Rv0015c.1	7	3ret_SAL_A_201 PDB CREDO	0.597	0.183	0.533	0.007
Rv0015c.1	9	3ogp_017_A_200 PDB CREDO	0.688	0.090	0.533	0.007
Rv0015c.1	14	1fk9_EFZ_A_999 PDB CREDO	0.715	0.070	0.532	0.007
Rv0015c.1	14	1err_RAL_A_600 PDB CREDO	0.647	0.127	0.532	0.007
Rv0015c.1	14	1s9p_DES_C_500 PDB CREDO	0.714	0.071	0.532	0.007
Rv0015c.1	27	1jg3_ADN_B_550 PDB CREDO	0.625	0.150	0.532	0.007
Rv0015c.1	10	2prg_BRL_B_2 PDB CREDO	0.549	0.245	0.531	0.007
Rv0015c.1	10	3erd_DES_B_800 PDB CREDO	0.569	0.217	0.531	0.007
Rv0015c.1	9	2qxs_RAL_A_600 PDB CREDO	0.837	0.013	0.530	0.007
Rv0015c.1	14	1s9p_DES_B_459 PDB CREDO	0.711	0.072	0.530	0.007
Rv0015c.1	14	3ads_IMN_A_2 PDB CREDO	0.549	0.246	0.530	0.007
Rv0015c.1	14	2oiq_STI_A_1001 PDB CREDO	0.685	0.093	0.530	0.007
Rv0015c.1	9	1p93_DEX_D_4999 PDB CREDO	0.586	0.197	0.530	0.007
Rv0015c.1	10	3erd_DES_A_600 PDB CREDO	0.568	0.219	0.529	0.007
Rv0015c.1	14	2jfa_RAL_B_600 PDB CREDO	0.643	0.131	0.529	0.007
Rv0015c.1	27	1z9y_FUN_A_500 PDB CREDO	0.646	0.128	0.529	0.007
Rv0015c.1	14	2gqg_1N1_B_502 PDB CREDO	0.566	0.222	0.529	0.007
Rv0015c.1	27	1jip_KTN_A_801 PDB CREDO	0.551	0.242	0.529	0.007
Rv0015c.1	14	1err_RAL_B_600 PDB CREDO	0.643	0.132	0.529	0.007
Rv0015c.1	14	1d4s_TPV_A_201 PDB CREDO	0.547	0.248	0.529	0.007
Rv0015c.1	27	3mdz_EZL_A_264 PDB CREDO	0.551	0.242	0.528	0.007
Rv0015c.1	21	3jwq_VIA_D_901 PDB CREDO	0.547	0.248	0.528	0.007
Rv0015c.1	9	2qxs_RAL_B_600 PDB CREDO	0.834	0.014	0.528	0.007
Rv0015c.1	9	1sa1_POD_D_701 PDB CREDO	0.682	0.095	0.528	0.007
Rv0015c.1	9	3adx_IMN_B_3 PDB CREDO	0.737	0.055	0.528	0.007
Rv0015c.1	14	3nrr_D16_B_520 PDB CREDO	0.546	0.249	0.528	0.007
Rv0015c.1	10	3bbt_FMM_B_91 PDB CREDO	0.633	0.142	0.528	0.007
Rv0015c.1	27	3sxr_1N1_B_2 PDB CREDO	0.573	0.213	0.527	0.007
Rv0015c.1	4	3ik6_HCZ_B_262 PDB CREDO	0.613	0.164	0.527	0.007
Rv0015c.1	14	3ln1_CEL_C_682 PDB CREDO	0.582	0.201	0.527	0.007
Rv0015c.1	9	3jwq_VIA_D_901 PDB CREDO	0.527	0.278	0.527	0.007
Rv0015c.1	14	3ln1_CEL_A_682 PDB CREDO	0.582	0.202	0.526	0.007
Rv0015c.1	14	3ln1_CEL_B_682 PDB CREDO	0.582	0.202	0.526	0.007
Rv0015c.1	14	3hec_STI_A_1 PDB CREDO	0.620	0.156	0.526	0.007
Rv0015c.1	10	3ln1_CEL_B_682 PDB CREDO	0.601	0.177	0.526	0.007
Rv0015c.1	9	3d90_NOG_B_2001 PDB CREDO	0.544	0.253	0.525	0.007
Rv0015c.1	14	1y0x_T44_X_500 PDB CREDO	0.659	0.116	0.525	0.007
Rv0015c.1	10	3frq_ERY_B_195 PDB CREDO	0.641	0.134	0.525	0.007
Rv0015c.1	9	1m2z_DEX_D_401 PDB CREDO	0.580	0.203	0.525	0.007
Rv0015c.1	9	3gn8_DEX_A_247 PDB CREDO	0.580	0.203	0.525	0.007
Rv0015c.1	9	3mne_DEX_A_784 PDB CREDO	0.580	0.203	0.525	0.007
Rv0015c.1	10	3ln1_CEL_C_682 PDB CREDO	0.601	0.178	0.525	0.007
Rv0015c.1	10	3ads_IMN_A_2 PDB CREDO	0.525	0.281	0.525	0.008
Rv0015c.1	10	3ln1_CEL_A_682 PDB CREDO	0.600	0.180	0.524	0.008
Rv0015c.1	4	3lfa_1N1_A_361 PDB CREDO	0.686	0.091	0.524	0.008
Rv0015c.1	9	3el0_1UN_A_201 PDB CREDO	0.783	0.032	0.524	0.008
Rv0015c.1	4	1xbb_STI_A_1 PDB CREDO	0.550	0.244	0.524	0.008
Rv0015c.1	9	3d90_NOG_A_1001 PDB CREDO	0.542	0.256	0.524	0.008
Rv0015c.1	10	2h42_VIA_C_903 PDB CREDO	0.562	0.228	0.523	0.008
Rv0015c.1	27	1sn5_T3_C_601 PDB CREDO	0.523	0.283	0.523	0.008
Rv0015c.1	9	1p93_DEX_C_3999 PDB CREDO	0.578	0.206	0.523	0.008
Rv0015c.1	4	3ijx_HCZ_B_800 PDB CREDO	0.577	0.208	0.523	0.008
Rv0015c.1	9	1a28_STR_A_1 PDB CREDO	0.560	0.230	0.523	0.008
Rv0015c.1	10	1nhz_486_A_800 PDB CREDO	0.559	0.232	0.522	0.008
Rv0015c.1	9	1m2z_DEX_A_301 PDB CREDO	0.577	0.208	0.522	0.008
Rv0015c.1	9	3gn8_DEX_B_247 PDB CREDO	0.577	0.208	0.522	0.008
Rv0015c.1	9	3heg_BAX_A_1 PDB CREDO	0.674	0.102	0.522	0.008
Rv0015c.1	14	2zi9_CL9_A_401 PDB CREDO	0.601	0.177	0.522	0.008
Rv0015c.1	14	3jwq_VIA_D_901 PDB CREDO	0.522	0.285	0.522	0.008
Rv0015c.1	4	2jih_097_A_1001 PDB CREDO	0.576	0.209	0.521	0.008
Rv0015c.1	14	3heg_BAX_A_1 PDB CREDO	0.673	0.103	0.521	0.008
Rv0015c.1	10	2xpv_MIY_A_1209 PDB CREDO	0.539	0.260	0.520	0.008
Rv0015c.1	9	1n49_RIT_B_301 PDB CREDO	0.798	0.025	0.520	0.008
Rv0015c.1	10	1jg2_ADN_A_500 PDB CREDO	0.520	0.288	0.520	0.008
Rv0015c.1	14	3erd_DES_B_800 PDB CREDO	0.577	0.207	0.520	0.008
Rv0015c.1	21	3qt0_486_A_4 PDB CREDO	0.538	0.261	0.520	0.008
Rv0015c.1	9	3ufn_ROC_A_401 PDB CREDO	0.888	0.004	0.519	0.008
Rv0015c.1	21	1uwh_BAX_A_1723 PDB CREDO	0.673	0.103	0.518	0.008
Rv0015c.1	21	3bbt_FMM_D_91 PDB CREDO	0.537	0.263	0.518	0.008
Rv0015c.1	4	3hgx_SAL_A_102 PDB CREDO	0.670	0.106	0.518	0.008
Rv0015c.1	4	3ijx_HCZ_D_800 PDB CREDO	0.708	0.075	0.518	0.008
Rv0015c.1	10	1ya3_STR_A_1001 PDB CREDO	0.518	0.291	0.518	0.008
Rv0015c.1	14	3o1c_ADN_A_127 PDB CREDO	0.597	0.183	0.518	0.008
Rv0015c.1	21	1uwh_BAX_B_1723 PDB CREDO	0.672	0.104	0.517	0.008
Rv0015c.1	21	1s9p_DES_A_459 PDB CREDO	0.536	0.264	0.517	0.008
Rv0015c.1	4	1sn5_T3_D_602 PDB CREDO	0.595	0.185	0.517	0.008
Rv0015c.1	27	3sxr_1N1_A_1 PDB CREDO	0.584	0.198	0.517	0.008
Rv0015c.1	4	3mdv_CL6_B_506 PDB CREDO	0.543	0.254	0.517	0.008
Rv0015c.1	10	3oht_1N1_A_1000 PDB CREDO	0.597	0.183	0.517	0.008
Rv0015c.1	9	2oax_SNL_D_4001 PDB CREDO	0.667	0.108	0.516	0.009
Rv0015c.1	10	2q1v_PDN_A_248 PDB CREDO	0.516	0.294	0.516	0.009
Rv0015c.1	14	2hyy_STI_A_600 PDB CREDO	0.728	0.061	0.516	0.009
Rv0015c.1	14	3pyy_STI_A_3 PDB CREDO	0.728	0.061	0.516	0.009
Rv0015c.1	9	2fum_MIX_D_3539 PDB CREDO	0.515	0.294	0.515	0.009
Rv0015c.1	9	2h42_VIA_C_903 PDB CREDO	0.573	0.213	0.515	0.009
Rv0015c.1	9	3k54_1N1_A_1 PDB CREDO	0.594	0.186	0.515	0.009
Rv0015c.1	9	3oht_1N1_A_1000 PDB CREDO	0.616	0.160	0.515	0.009
Rv0015c.1	9	2oax_SNL_E_5001 PDB CREDO	0.666	0.110	0.515	0.009
Rv0015c.1	14	3ms9_STI_A_1 PDB CREDO	0.727	0.062	0.515	0.009
Rv0015c.1	14	2j7y_E3O_A_1454 PDB CREDO	0.639	0.135	0.515	0.009
Rv0015c.1	14	4eb6_VLB_C_503 PDB CREDO	0.572	0.214	0.515	0.009
Rv0015c.1	9	2oax_SNL_A_1001 PDB CREDO	0.665	0.110	0.515	0.009
Rv0015c.1	7	3fl9_TOP_D_200 PDB CREDO	0.545	0.252	0.514	0.009
Rv0015c.1	10	1ya3_STR_B_2001 PDB CREDO	0.514	0.296	0.514	0.009
Rv0015c.1	21	3jwq_VIA_B_901 PDB CREDO	0.552	0.241	0.514	0.009
Rv0015c.1	14	2hyy_STI_D_600 PDB CREDO	0.725	0.063	0.514	0.009
Rv0015c.1	14	3ms9_STI_B_1 PDB CREDO	0.725	0.063	0.514	0.009
Rv0015c.1	4	3uq6_ADN_B_401 PDB CREDO	0.539	0.260	0.514	0.009
Rv0015c.1	9	2oax_SNL_F_6001 PDB CREDO	0.664	0.111	0.514	0.009
Rv0015c.1	9	1ya3_STR_C_3001 PDB CREDO	0.592	0.189	0.514	0.009
Rv0015c.1	27	3ri5_IVM_E_349 PDB CREDO	0.581	0.203	0.514	0.009
Rv0015c.1	4	1ie4_T44_A_128 PDB CREDO	0.702	0.080	0.514	0.009
Rv0015c.1	14	3vn2_TLS_A_501 PDB CREDO	0.624	0.151	0.513	0.009
Rv0015c.1	14	3pyy_STI_B_4 PDB CREDO	0.725	0.063	0.513	0.009
Rv0015c.1	4	2oa1_ADN_B_2005 PDB CREDO	0.629	0.146	0.513	0.009
Rv0015c.1	9	2aa5_STR_A_301 PDB CREDO	0.549	0.246	0.513	0.009
Rv0015c.1	9	2aa5_STR_B_302 PDB CREDO	0.549	0.246	0.513	0.009
Rv0015c.1	7	3fl9_TOP_F_200 PDB CREDO	0.543	0.254	0.513	0.009
Rv0015c.1	14	2hyy_STI_C_600 PDB CREDO	0.724	0.064	0.513	0.009
Rv0015c.1	14	3mss_STI_C_1 PDB CREDO	0.724	0.064	0.513	0.009
Rv0015c.1	7	1uay_ADN_B_1002 PDB CREDO	0.513	0.299	0.513	0.009
Rv0015c.1	27	1sn0_T44_C_601 PDB CREDO	0.584	0.199	0.512	0.009
Rv0015c.1	21	2h42_VIA_B_902 PDB CREDO	0.550	0.244	0.512	0.009
Rv0015c.1	9	1sa1_POD_B_700 PDB CREDO	0.682	0.095	0.512	0.009
Rv0015c.1	14	3mss_STI_D_1 PDB CREDO	0.723	0.064	0.512	0.009
Rv0015c.1	27	2ity_IRE_A_2020 PDB CREDO	0.579	0.205	0.512	0.009
Rv0015c.1	14	2xkw_P1B_B_1475 PDB CREDO	0.569	0.218	0.512	0.009
Rv0015c.1	21	3adx_IMN_A_2 PDB CREDO	0.549	0.245	0.512	0.009
Rv0015c.1	21	3k54_1N1_A_1 PDB CREDO	0.570	0.217	0.512	0.009
Rv0015c.1	27	3s20_CER_B_1 PDB CREDO	0.670	0.106	0.512	0.009
Rv0015c.1	9	2ab2_SNL_B_503 PDB CREDO	0.603	0.176	0.511	0.009
Rv0015c.1	14	2prg_BRL_B_2 PDB CREDO	0.548	0.246	0.511	0.009
Rv0015c.1	21	3h0a_9RA_A_500 PDB CREDO	0.529	0.274	0.511	0.009
Rv0015c.1	14	1iep_STI_B_202 PDB CREDO	0.722	0.065	0.511	0.009
Rv0015c.1	14	3mss_STI_A_1 PDB CREDO	0.722	0.065	0.511	0.009
Rv0015c.1	21	2x9g_LYA_C_1270 PDB CREDO	0.511	0.301	0.511	0.009
Rv0015c.1	7	3fl9_TOP_E_200 PDB CREDO	0.541	0.256	0.511	0.009
Rv0015c.1	10	3oct_1N1_A_663 PDB CREDO	0.511	0.302	0.511	0.009
Rv0015c.1	21	2x9g_LYA_D_1270 PDB CREDO	0.511	0.302	0.511	0.009
Rv0015c.1	14	3gvu_STI_A_1001 PDB CREDO	0.721	0.066	0.511	0.009
Rv0015c.1	14	3mss_STI_B_1 PDB CREDO	0.721	0.066	0.511	0.009
Rv0015c.1	9	2oax_SNL_C_3001 PDB CREDO	0.601	0.177	0.510	0.009
Rv0015c.1	14	2x9g_LYA_D_1270 PDB CREDO	0.528	0.275	0.510	0.009
Rv0015c.1	9	2ab2_SNL_A_502 PDB CREDO	0.600	0.179	0.509	0.009
Rv0015c.1	4	3uq6_ADN_A_401 PDB CREDO	0.534	0.266	0.509	0.009
Rv0015c.1	14	1iep_STI_A_201 PDB CREDO	0.719	0.067	0.509	0.009
Rv0015c.1	14	2x9g_LYA_C_1270 PDB CREDO	0.527	0.277	0.509	0.009
Rv0015c.1	14	2hw2_RFP_A_1200 PDB CREDO	0.600	0.179	0.509	0.010
Rv0015c.1	14	2pl0_STI_A_200 PDB CREDO	0.658	0.117	0.509	0.010
Rv0015c.1	4	2jap_J01_A_1249 PDB CREDO	0.509	0.305	0.509	0.010
Rv0015c.1	4	2jap_J01_D_1249 PDB CREDO	0.509	0.305	0.509	0.010
Rv0015c.1	4	3ret_SAL_A_201 PDB CREDO	0.658	0.117	0.509	0.010
Rv0015c.1	9	2oax_SNL_B_2001 PDB CREDO	0.599	0.180	0.508	0.010
Rv0015c.1	9	3vhu_SNL_A_1001 PDB CREDO	0.599	0.180	0.508	0.010
Rv0015c.1	10	1ya4_CTX_C_3 PDB CREDO	0.659	0.116	0.508	0.010
Rv0015c.1	14	3k5v_STI_B_2 PDB CREDO	0.717	0.068	0.508	0.010
Rv0015c.1	27	2uxp_CLM_B_1211 PDB CREDO	0.606	0.172	0.508	0.010
Rv0015c.1	21	2hw2_RFP_A_1200 PDB CREDO	0.619	0.156	0.508	0.010
Rv0015c.1	10	1sqn_NDR_A_1001 PDB CREDO	0.526	0.279	0.508	0.010
Rv0015c.1	10	1ya4_CTX_B_2 PDB CREDO	0.658	0.117	0.508	0.010
Rv0015c.1	10	2cbr_A80_A_201 PDB CREDO	0.586	0.196	0.508	0.010
Rv0015c.1	4	2jap_J01_C_1249 PDB CREDO	0.508	0.307	0.508	0.010
Rv0015c.1	10	2h42_VIA_B_902 PDB CREDO	0.544	0.252	0.507	0.010
Rv0015c.1	27	3bl1_BL1_A_300 PDB CREDO	0.619	0.157	0.507	0.010
Rv0015c.1	4	3s20_CER_A_1 PDB CREDO	0.559	0.232	0.506	0.010
Rv0015c.1	10	3h52_486_C_4 PDB CREDO	0.544	0.253	0.506	0.010
Rv0015c.1	21	1gs4_ZK5_A_1918 PDB CREDO	0.544	0.253	0.506	0.010
Rv0015c.1	14	1uwj_BAX_B_1723 PDB CREDO	0.674	0.102	0.506	0.010
Rv0015c.1	10	1mx1_THA_E_5 PDB CREDO	0.563	0.226	0.506	0.010
Rv0015c.1	4	1qhs_CLM_A_999 PDB CREDO	0.530	0.272	0.505	0.010
Rv0015c.1	4	2nnj_225_A_501 PDB CREDO	0.530	0.272	0.505	0.010
Rv0015c.1	4	3ads_IMN_A_1 PDB CREDO	0.587	0.195	0.505	0.010
Rv0015c.1	14	3oht_1N1_B_1000 PDB CREDO	0.541	0.256	0.505	0.010
Rv0015c.1	6	3sm2_478_A_126 PDB CREDO	0.584	0.199	0.505	0.010
Rv0015c.1	21	4eb6_VLB_C_503 PDB CREDO	0.542	0.256	0.505	0.010
Rv0015c.1	9	1zgy_BRL_A_503 PDB CREDO	0.522	0.285	0.505	0.010
Rv0015c.1	21	1fm6_BRL_X_504 PDB CREDO	0.596	0.184	0.504	0.010
Rv0015c.1	6	1hwk_117_A_2 PDB CREDO	0.809	0.021	0.504	0.010
Rv0015c.1	21	2h42_VIA_A_901 PDB CREDO	0.521	0.285	0.504	0.010
Rv0015c.1	9	3ri5_IVM_E_349 PDB CREDO	0.675	0.101	0.503	0.010
Rv0015c.1	21	3ln1_CEL_A_682 PDB CREDO	0.575	0.210	0.503	0.010
Rv0015c.1	21	3ln1_CEL_C_682 PDB CREDO	0.575	0.210	0.503	0.010
Rv0015c.1	4	2jap_J01_B_1249 PDB CREDO	0.503	0.314	0.503	0.010
Rv0015c.1	9	3mnp_DEX_A_784 PDB CREDO	0.611	0.166	0.503	0.010
Rv0015c.1	9	1mx1_THA_B_2 PDB CREDO	0.731	0.059	0.503	0.010
Rv0015c.1	14	3v5w_8PR_A_701 PDB CREDO	0.555	0.237	0.502	0.011
Rv0015c.1	27	3g1u_ADN_B_438 PDB CREDO	0.567	0.220	0.502	0.011
Rv0015c.1	27	2ydo_ADN_A_400 PDB CREDO	0.547	0.248	0.502	0.011
Rv0015c.1	4	2bxe_1FL_A_2001 PDB CREDO	0.502	0.316	0.502	0.011
Rv0015c.1	4	2w03_ADN_A_1588 PDB CREDO	0.615	0.162	0.502	0.011
Rv0015c.1	4	3mg0_BO2_Y_1403 PDB CREDO	0.615	0.162	0.502	0.011
Rv0015c.1	27	3sv8_SV6_A_1 PDB CREDO	0.523	0.283	0.502	0.011
Rv0015c.1	10	1sqn_NDR_B_2001 PDB CREDO	0.519	0.288	0.502	0.011
Rv0015c.1	6	1hwk_117_C_4 PDB CREDO	0.805	0.023	0.502	0.011
Rv0015c.1	9	1dtl_BEP_A_204 PDB CREDO	0.700	0.080	0.501	0.011
Rv0015c.1	10	3vn2_TLS_A_501 PDB CREDO	0.631	0.144	0.501	0.011
Rv0015c.1	14	4asd_BAX_A_1500 PDB CREDO	0.667	0.108	0.501	0.011
Rv0015c.1	7	3ug2_IRE_A_1 PDB CREDO	0.691	0.088	0.501	0.011
Rv0015c.1	14	1uob_PNN_A_1311 PDB CREDO	0.648	0.127	0.501	0.011
Rv0015c.1	10	3adx_IMN_B_3 PDB CREDO	0.676	0.100	0.501	0.011
Rv0015c.1	9	2fum_MIX_A_539 PDB CREDO	0.556	0.235	0.501	0.011
Rv0015c.1	7	2bxg_IBP_B_2002 PDB CREDO	0.501	0.317	0.501	0.011
Rv0015c.1	21	3ln1_CEL_B_682 PDB CREDO	0.573	0.213	0.501	0.011
Rv0015c.1	27	2ito_IRE_A_2020 PDB CREDO	0.612	0.165	0.501	0.011
Rv0015c.1	4	3hgx_SAL_B_104 PDB CREDO	0.647	0.127	0.501	0.011
Rv0015c.1	4	2itz_IRE_A_2021 PDB CREDO	0.712	0.072	0.500	0.011
Rv0015c.1	27	1jg3_ADN_A_500 PDB CREDO	0.659	0.116	0.500	0.011
Rv0015c.1	21	2gqg_1N1_A_501 PDB CREDO	0.537	0.262	0.500	0.011

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Target name	CHEMBL ID	SMILES
Plk1(PBD)	CC(C)C1=CC(=O)C(C)=CC1=O
Plk1(PBD)	CC(C)C1=CC(=N/O)C(C)=CC1=O

STITCH interactions

No high confidence interactions