Rv2145c

Tuberculist information
Gene namewag31
Protein functionDiviva family protein Wag31
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2404.62
Molecular mass(da)28277.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 260
	  		  	1    MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLRQRINELDQEL   60
			  	61   AAGGGAGVTPQATQAIPAYEPEPGKPAPAAVSAGMNEEQALKAARVLSLAQDTADRLTNT  120
			  	121  AKAESDKMLADARANAEQILGEARHTADATVAEARQRADAMLADAQSRSEAQLRQAQEKA  180
			  	181  DALQADAERKHSEIMGTINQQRAVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSA  240
			  	241  APVDSNADAGGFDQFNRGKN

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 3 to 64  |  Coverage: 23% DivIVA Range: 11 to 229  |  Coverage: 83% 1
Number of amino acids : 260
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DivIVAPF051033-64
Mtb Structural Proteome models
Model Number1
Model nameRv2145c
Template1JAD    APDBCREDO
Template coverage14_241
Template Identity(%)13.7
Model coverage(%)83.8
Normalized DOPE score-0.297

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2145cGene nameConfidence Score
Rv0015cpknA0.966
Rv2150cftsZ0.939
Rv2150cftsZ0.939
Rv2146cRv2146c0.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions