Rv3917c

Tuberculist information
Gene nameparB
Protein functionProbable chromosome partitioning protein ParB
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)4405.46
Molecular mass(da)37018.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 344
	  		  	1    MTQPSRRKGGLGRGLAALIPTGPADGESGPPTLGPRMGSATADVVIGGPVPDTSVMGAIY   60
			  	61   REIPPSAIEANPRQPRQVFDEEALAELVHSIREFGLLQPIVVRSLAGSQTGVRYQIVMGE  120
			  	121  RRWRAAQEAGLATIPAIVRETGDDNLLRDALLENIHRVQLNPLEEAAAYQQLLDEFGVTH  180
			  	181  DELAARIGRSRPLITNMIRLLKLPIPVQRRVAAGVLSAGHARALLSLEAGPEAQEELASR  240
			  	241  IVAEGLSVRATEETVTLANHEANRQAHHSDATTPAPPRRKPIQMPGLQDVAERLSTTFDT  300
			  	301  RVTVSLGKRKGKIVVEFGSVDDLARIVGLMTTDGRDKGLHRDAL

Known structures in the PDB
No Known structures
1 35 69 103 137 171 205 239 273 307 341 Range: 61 to 155  |  Coverage: 27% ParBc Range: 175 to 269  |  Coverage: 27% KorB Range: 60 to 254  |  Coverage: 56% 1 Range: 58 to 285  |  Coverage: 65% 1 Range: 146 to 260  |  Coverage: 33% 2
Number of amino acids : 344
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ParBcPF0219561-155
KorBPF08535175-269
Mtb Structural Proteome models
Model Number1
Model nameRv3917c
Template1VZ0    APDBCREDO
Template coverage23_209
Template Identity(%)48.1
Model coverage(%)56.4
Normalized DOPE score0.265

Structure Models from Chopin
Model Number1
Profiled.268.1.2
Click for model details
zscore35.73
Residue begin58
Residue end285
Model Number2
Profilea.4.14.1
Click for model details
zscore21.53
Residue begin146
Residue end260
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3917cGene nameConfidence Score
Rv3918cparA0.999
Rv1708Rv17080.996
Rv3213cRv3213c0.996
Rv3919cgid0.987
Rv0001dnaA0.96
Rv0001dnaA0.96
Rv3924crpmH0.949
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions