Rv1708

Tuberculist information
Gene nameRv1708
Protein functionPutative initiation inhibitor protein
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1936.36
Molecular mass(da)34362.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 318
	  		  	1    LPAGLPGQASVAVRLSCDVPPDARHHEPRPGMTDHPDTGNGIGLTGRPPRAIPDPAPRSS   60
			  	61   HGPAKVIAMCNQKGGVGKTTSTINLGAALGEYGRRVLLVDMDPQGALSAGLGVPHYELDK  120
			  	121  TIHNVLVEPRVSIDDVLIHSRVKNMDLVPSNIDLSAAEIQLVNEVGREQTLARALYPVLD  180
			  	181  RYDYVLIDCQPSLGLLTVNGLACTDGVIIPTECEFFSLRGLALLTDTVDKVRDRLNPKLD  240
			  	241  ISGILITRYDPRTVNSREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSA  300
			  	301  GALAYRALARELIDRFGM

Known structures in the PDB
No Known structures
1 32 63 94 125 156 187 218 249 280 311 Range: 67 to 284  |  Coverage: 68% CbiA Range: 67 to 315  |  Coverage: 77% 1 Range: 3 to 318  |  Coverage: 99% 1
Number of amino acids : 318
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
CbiAPF0165667-284
Mtb Structural Proteome models
Model Number1
Model nameRv1708
Template1WCV    1PDBCREDO
Template coverage9_245
Template Identity(%)46.8
Model coverage(%)78.0
Normalized DOPE score-1.455

Structure Models from Chopin
Model Number1
Profilec.37.1.10 - 3.40.50.300
Click for model details
zscore11.43
Residue begin3
Residue end318
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1708Gene nameConfidence Score
Rv3917cparB0.996
Rv3917cparB0.996
Rv1709scpA0.91
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions