Rv3542c

Tuberculist information
Gene nameRv3542c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3981.04
Molecular mass(da)33939.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 311
	  		  	1    VTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVDDAAARAAGHP   60
			  	61   GIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYIGVVATNCEQTYHRYLLPGEQ  120
			  	121  VSISAELGDVVGPKQTALGEGWFINQHIVWQVGDEDVAEMNWRILKFKPAGSPSSVPDDL  180
			  	181  DPDAMMRPSSSRDTAFFWDGVKAHELRIQRLADGSLRHPPVPAVWQDKSVPINYVVSSGR  240
			  	241  GTVFSFVVHHAPKVPGRTVPFVIALVELEEGVRMLGELRGADPARVAIGMPVRATYIDFP  300
			  	301  DWSLYAWEPDE

Known structures in the PDB
No Known structures
1 32 63 94 125 156 187 218 249 280 311 Range: 19 to 160  |  Coverage: 45% zf-MaoC Range: 234 to 297  |  Coverage: 20% DUF35 Range: 9 to 281  |  Coverage: 87% 1 Range: 19 to 160  |  Coverage: 45% 1
Number of amino acids : 311
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
zf-MaoCPF1345219-160
DUF35PF01796234-297
Mtb Structural Proteome models
Model Number1
Model nameRv3542c
Template2BI0    APDBCREDO
Template coverage12_271
Template Identity(%)16.2
Model coverage(%)87.5
Normalized DOPE score0.712

Structure Models from Chopin
Model Number1
Profiled.38.1.4 - 3.10.129.10
Click for model details
zscore13.82
Residue begin19
Residue end160
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3542cGene nameConfidence Score
Rv3541cRv3541c0.998
Rv3540cltp20.995
Rv3540cltp20.995
Rv3543cfadE290.986
Rv3543cfadE290.986
Rv3543cfadE290.986
Rv3544cfadE280.959
Rv3544cfadE280.959
Rv3545ccyp1250.924
Rv0504cRv0504c0.921
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions