Rv3422c

Tuberculist information
Gene nameRv3422c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3839.69
Molecular mass(da)18195.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 168
	  		  	1    LSREGIRRRPKARAGLTGGGTATLPRVEDTLTLGSRLGEQLCAGDVVVLSGPLGAGKTVL   60
			  	61   AKGIAMAMDVEGPITSPTFVLARMHRPRRPGTPAMVHVDVYRLLDHNSADLLSELDSLDL  120
			  	121  DTDLEDAVVVVEWGEGLAERLSQRHLDVRLERVSHSDTRIATWSWGRS

Known structures in the PDB
No Known structures
1 17 33 49 65 81 97 113 129 145 161 Range: 30 to 160  |  Coverage: 77% UPF0079 Range: 19 to 165  |  Coverage: 86% 1 Range: 17 to 168  |  Coverage: 89% 1
Number of amino acids : 168
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UPF0079PF0236730-160
Mtb Structural Proteome models
Model Number1
Model nameRv3422c
Template1HTW    APDBCREDO
Template coverage3_145
Template Identity(%)25.2
Model coverage(%)86.9
Normalized DOPE score-0.463

Structure Models from Chopin
Model Number1
Profilec.37.1.18 - 3.40.50.300
Click for model details
zscore28.31
Residue begin17
Residue end168
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3422cGene nameConfidence Score
Rv3420crimI0.995
Rv3421cRv3421c0.99
Rv3419cgcp0.989
Rv3423calr0.986
Rv3423calr0.986
Rv3433cRv3433c0.927
Rv3433cRv3433c0.927
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions