Rv3420c

Tuberculist information
Gene namerimI
Protein functionRibosomal-protein-alanine acetyltransferase RimI (acetylating enzyme for N-terminal of ribosomal protein S18)
Functional category(tuberculist)information pathways
Gene location(kb)3838.59
Molecular mass(da)17357.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 158
	  		  	1    VTADTEPVTIGALTRADAQRCAELEAQLFVGDDPWPPAAFNRELASPHNHYVGARSGGTL   60
			  	61   VGYAGISRLGRTPPFEYEVHTIGVDPAYQGRGIGRRLLRELLDFARGGVVYLEVRTDNDA  120
			  	121  ALALYRSVGFQRVGLRRRYYRVSGADAYTMRRDSGDPS

Known structures in the PDB
No Known structures
1 16 31 46 61 76 91 106 121 136 151 Range: 54 to 131  |  Coverage: 48% Acetyltransf_1 Range: 6 to 155  |  Coverage: 94% 1 Range: 1 to 145  |  Coverage: 91% 1
Number of amino acids : 158
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Acetyltransf_1PF0058354-131
Mtb Structural Proteome models
Model Number1
Model nameRv3420c
Template2GE3    APDBCREDO
Template coverage6_169
Template Identity(%)26.0
Model coverage(%)94.3
Normalized DOPE score-0.426

Structure Models from Chopin
Model Number1
Profiled.108.1.5
Click for model details
zscore15.07
Residue begin1
Residue end145
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3420cGene nameConfidence Score
Rv3419cgcp0.998
Rv3421cRv3421c0.995
Rv3422cRv3422c0.995
Rv3423calr0.973
Rv3423calr0.973
Rv0995rimJ0.929
Rv2977cthiL0.912
Rv2977cthiL0.912
Rv2727cmiaA0.911
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
acetyl-CoAPubChem0.8809.571
AcCoAPubChem0.754809.571