Rv3421c

Tuberculist information
Gene nameRv3421c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3839.06
Molecular mass(da)21571.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 211
	  		  	1    MSRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAAL   60
			  	61   TMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTD  120
			  	121  ARRREVYWARYCDGIRTVGPAVNAAADVDPGPALAVAGAPEHAALFALPCVEPSRPSPAG  180
			  	181  LVAAVNWADKPAPLVPLYLRRPDAKPLAVCT

Known structures in the PDB
No Known structures
1 22 43 64 85 106 127 148 169 190 211 Range: 32 to 184  |  Coverage: 72% Peptidase_M22 Range: 7 to 201  |  Coverage: 91% 1 Range: 6 to 127  |  Coverage: 57% 1
Number of amino acids : 211
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Peptidase_M22PF0081432-184
Mtb Structural Proteome models
Model Number1
Model nameRv3421c
Template2A6A    APDBCREDO
Template coverage1_193
Template Identity(%)27.5
Model coverage(%)91.9
Normalized DOPE score0.464

Structure Models from Chopin
Model Number1
Profilec.55.1.9
Click for model details
zscore11.2
Residue begin6
Residue end127
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3421cGene nameConfidence Score
Rv3419cgcp0.998
Rv3420crimI0.995
Rv3422cRv3422c0.99
Rv3423calr0.942
Rv3423calr0.942
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions