Rv3084

Tuberculist information
Gene namelipR
Protein functionProbable acetyl-hydrolase/esterase LipR
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3450
Molecular mass(da)32616.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 308
	  		  	1    MNLRKNVIRSVLRGARPLFASRRLGIAGRRVLLATLTAGARAPKGTRFQRVSIAGVPVQR   60
			  	61   VQPPHAATSGTLIYLHGGAYALGSARGYRGLAAQLAAAAGMTALVPDYTRAPHAHYPVAL  120
			  	121  EEMAAVYTRLLDDGLDPKTTVIAGDSAGGGLTLALAMALRDRGIQAPAALGLICPWADLA  180
			  	181  VDIEATRPALRDPLILPSMCTEWAPRYVGSSDPRLPGISPVYGDMSGLPPIVMQTAGDDP  240
			  	241  ICVDADKIETACAASKTSIEHRRFAGMWHDFHLQVSLLPEARDAIADLGARLRGHLHQSQ  300
			  	301  GQPRGVVK

Known structures in the PDB
No Known structures
1 31 61 91 121 151 181 211 241 271 301 Range: 72 to 273  |  Coverage: 65% Abhydrolase_3 Range: 3 to 297  |  Coverage: 95% 1 Range: 1 to 302  |  Coverage: 97% 1
Number of amino acids : 308
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Abhydrolase_3PF0785972-273
Mtb Structural Proteome models
Model Number1
Model nameRv3084
Template1U4N    APDBCREDO
Template coverage3_310
Template Identity(%)24.1
Model coverage(%)95.5
Normalized DOPE score-0.362

Structure Models from Chopin
Model Number1
Profilec.69.1.2 - 3.40.50.1820
Click for model details
zscore21.54
Residue begin1
Residue end302
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3084Gene nameConfidence Score
Rv3085Rv30850.953
Rv3083Rv30830.938
Rv1777cyp1440.909
Rv3086adhD0.907
Rv3086adhD0.907
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions