Rv3085

Tuberculist information
Gene nameRv3085
Protein functionProbable short-chain type dehydrogenase/reductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3450.92
Molecular mass(da)29217.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 276
	  		  	1    MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSD   60
			  	61   RLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVN  120
			  	121  GTKAFLPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPV  180
			  	181  KVTCVHPGGIKTAVARNATVADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARV  240
			  	241  VVGLEAKAVDVLARIMGSSYQRLVAAGVAKFFPWAK

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 7 to 174  |  Coverage: 60% adh_short Range: 3 to 256  |  Coverage: 91% 1 Range: 1 to 276  |  Coverage: 99% 1
Number of amino acids : 276
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_shortPF001067-174
Mtb Structural Proteome models
Model Number1
Model nameRv3085
Template1YB1    APDBCREDO
Template coverage28_268
Template Identity(%)31.7
Model coverage(%)91.7
Normalized DOPE score-0.156

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore19.8
Residue begin1
Residue end276
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3085Gene nameConfidence Score
Rv3086adhD0.956
Rv3086adhD0.956
Rv3083Rv30830.955
Rv3084lipR0.953
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions