Rv3011c

Tuberculist information
Gene namegatA
Protein functionProbable glutamyl-tRNA(GLN) amidotransferase (subunit A) GatA (Glu-ADT subunit A)
Functional category(tuberculist)information pathways
Gene location(kb)3369.95
Molecular mass(da)51388.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 494
	  		  	1    VTDIIRSDAATLAAKIAIKEVSSAEITRACLDQIEATDETYHAFLHVAADEALAAAAAID   60
			  	61   KQVAAGEPLPSALAGVPLALKDVFTTSDMPTTCGSKILEGWRSPYDATLTARLRAAGIPI  120
			  	121  LGKTNMDEFAMGSSTENSAYGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGS  180
			  	181  IRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDS  240
			  	241  TSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAAVEQLTALGAE  300
			  	301  VSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRVGDDGTRSAEEVMAMTRAAGF  360
			  	361  GPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLDAAYRSVDVLVSPTTPTTAFRL  420
			  	421  GEKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVG  480
			  	481  AAYEAARGPLLSAI

Known structures in the PDB
No Known structures
1 50 99 148 197 246 295 344 393 442 491 Range: 25 to 477  |  Coverage: 91% Amidase Range: 8 to 484  |  Coverage: 96% 1 Range: 1 to 494  |  Coverage: 99% 1
Number of amino acids : 494
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
AmidasePF0142525-477
Mtb Structural Proteome models
Model Number1
Model nameRv3011c
Template2F2A    APDBCREDO
Template coverage7_473
Template Identity(%)47.3
Model coverage(%)96.4
Normalized DOPE score-0.655

Structure Models from Chopin
Model Number1
Profilec.117.1.1 - 3.90.1300.10
Click for model details
zscore62.76
Residue begin1
Residue end494
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3011cGene nameConfidence Score
Rv3009cgatB0.999
Rv3009cgatB0.999
Rv3012cgatC0.999
Rv2725chflX0.967
Rv2725chflX0.967
Rv2388chemN0.954
Rv2388chemN0.954
Rv2572caspS0.924
Rv2572caspS0.924
Rv2572caspS0.924
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.74865.409
magnesiumPubChem0.72824.305