Rv3012c

Tuberculist information
Gene namegatC
Protein functionProbable glutamyl-tRNA(GLN) amidotransferase (subunit C) GatC (Glu-ADT subunit C)
Functional category(tuberculist)information pathways
Gene location(kb)3371.43
Molecular mass(da)10716
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 99
	  		  	1    VSQISRDEVAHLARLARLALTETELDSFAGQLDAILTHVSQIQAVDVTGVQATDNPLKDV   60
			  	61   NVTRPDETVPCLTQRQVLDQAPDAVDGRFAVPQILGDEQ

Known structures in the PDB
No Known structures
1 10 19 28 37 46 55 64 73 82 91 Range: 20 to 91  |  Coverage: 71% Glu-tRNAGln Range: 3 to 94  |  Coverage: 91% 1 Range: 3 to 94  |  Coverage: 91% 1
Number of amino acids : 99
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Glu-tRNAGlnPF0268620-91
Mtb Structural Proteome models
Model Number1
Model nameRv3012c
Template2F2A    CPDBCREDO
Template coverage3_94
Template Identity(%)35.9
Model coverage(%)91.9
Normalized DOPE score0.722

Structure Models from Chopin
Model Number1
Profilea.137.12.1
Click for model details
zscore23.75
Residue begin3
Residue end94
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3012cGene nameConfidence Score
Rv3009cgatB0.999
Rv3011cgatA0.999
Rv3009cgatB0.999
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
manganesePubChem0.78654.938
L-asparaginePubChem0.786132.118
magnesiumPubChem0.78624.305
adenosine diphosphatePubChem0.786427.201
polyglutaminePubChem0.786146.145