Tuberculist information
Gene namembtC
Protein functionPolyketide synthetase MbtC (polyketide synthase)
Functional category(tuberculist)lipid metabolism
Gene location(kb)2670.27
Molecular mass(da)46624.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 444
	  		  	1    MSDNDPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGF   60
			  	61   KPIHNLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHD  120
			  	121  VGCYVGASALEYGPALTEFSHHSGHLITGTSLGVISGRIAYTLDLAGPALTVDTSCSSAL  180
			  	181  AAFHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWA  240
			  	241  EGAAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAV  300
			  	301  VPADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGL  360
			  	361  VKVILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGT  420
			  	421  NSHVIVSMPDTVSAPERGPECGEV
			  			

Known structures in the PDB
No Known structures
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ketoacyl-syntPF001094-254
Ketoacyl-synt_CPF02801262-379
Mtb Structural Proteome models
Model Number1
Model nameRv2382c
Template2HG4    APDBCREDO
Template coverage39_468
Template Identity(%)47.3
Model coverage(%)97.1
Normalized DOPE score-0.576

Structure Models from Chopin
Model Number1
Profilec.95.1.1
Click for model details
zscore8.45
Residue begin82
Residue end335
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2382cGene nameConfidence Score
Rv2381cmbtD0.982
Rv2381cmbtD0.982
Rv2381cmbtD0.982
Rv2383cmbtB0.974
Rv2383cmbtB0.974
Rv2383cmbtB0.974
Rv2383cmbtB0.974
Rv2383cmbtB0.974
Rv2383cmbtB0.974
Rv2380cmbtE0.941
Rv2380cmbtE0.941
Rv2380cmbtE0.941
Rv2380cmbtE0.941
Rv2380cmbtE0.941
Rv2379cmbtF0.932
Rv2379cmbtF0.932
Rv2379cmbtF0.932
Rv2379cmbtF0.932
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions