SInCRe - Rv2231c

Tuberculist information

Gene name	cobC
Protein function	Possible aminotransferase CobC
Functional category(tuberculist)	intermediary metabolism and respiration
Gene location(kb)	2504.6
Molecular mass(da)	38904.7
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 364

	  		  	1    VLWILGPHTGPLLFDAVASLDTSPLAAARYHGDQDVAPGVLDFAVNVRHDRPPEWLVRQL   60
			  	61   AALLPELARYPSTDDVHRAQDAVAERHGRTRDEVLPLVGAAEGFALLHNLSPVRAAIVVP  120
			  	121  AFTEPAIALSAAGITAHHVVLKPPFVLDTAHVPDDADLVVVGNPTNPTSVLHLREQLLEL  180
			  	181  RRPGRILVVDEAFADWVPGEPQSLADDSLPDVLVLRSLTKTWSLAGLRVGYALGSPDVLA  240
			  	241  RLTVQRAHWPLGTLQLTAIAACCAPRAVAAAAADAVRLTALRAEMVAGLRSVGAEVVDGA  300
			  	301  APFVLFNIADADGLRNYLQSKGIAVRRGDTFVGLDARYLRAAVRPEWPVLVAAIAEWAKR  360
			  	361  GGRR

Known structures in the PDB

No Known structures

Number of amino acids : 364

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
Aminotran_1_2	PF00155	38-347

Mtb Structural Proteome models

Model Number	1
Model name	Rv2231c
Template	1LC5 APDB CREDO
Template coverage	26_354
Template Identity(%)	30.4
Model coverage(%)	86.5
Normalized DOPE score	-0.054

Model Number	2
Model name	Rv2231c.1
Template	1IAY APDB CREDO
Template coverage	11_435
Template Identity(%)	18.8
Model coverage(%)	99.2
Normalized DOPE score	0.414

Structure Models from Chopin

Model Number	1
Profile	c.67.1.1 Click for model details
zscore	21.58
Residue begin	1
Residue end	364

Binding pockets

STRING

Cytoscape Web will replace the contents of this div with protein-protein interaction network.

Protein interacting with Rv2231c	Gene name	Confidence Score
Rv0255c	cobQ1	0.967
Rv0255c	cobQ1	0.967
Rv2236c	cobD	0.94
Rv2848c	cobB	0.932
Rv2848c	cobB	0.932
Rv2232	ptkA	0.914

Potential ligand/drug binding sites

Protein Model	Pocket Number	Drug Binding Site	PMIN Score	Pvalue PMIN	PMAX Score	Pvalue PMAX
Rv2231c.1	3	1xkk_FMM_A_91 PDB CREDO	0.734	0.057	0.660	0.001
Rv2231c.1	3	1t46_STI_A_3 PDB CREDO	0.675	0.101	0.640	0.001
Rv2231c.1	2	1uwj_BAX_A_1723 PDB CREDO	0.657	0.118	0.638	0.001
Rv2231c.1	2	1iep_STI_B_202 PDB CREDO	0.637	0.138	0.637	0.001
Rv2231c.1	2	3pyy_STI_B_4 PDB CREDO	0.636	0.138	0.636	0.001
Rv2231c.1	2	3pyy_STI_A_3 PDB CREDO	0.635	0.140	0.635	0.001
Rv2231c.1	2	3mss_STI_A_1 PDB CREDO	0.634	0.141	0.634	0.001
Rv2231c.1	2	3mss_STI_B_1 PDB CREDO	0.633	0.142	0.633	0.001
Rv2231c.1	3	2qxs_RAL_A_600 PDB CREDO	0.632	0.142	0.632	0.001
Rv2231c.1	3	2qxs_RAL_B_600 PDB CREDO	0.632	0.142	0.632	0.001
Rv2231c.1	2	3gvu_STI_A_1001 PDB CREDO	0.632	0.143	0.632	0.001
Rv2231c.1	2	3ms9_STI_B_1 PDB CREDO	0.632	0.143	0.632	0.001
Rv2231c.1	2	2hyy_STI_D_600 PDB CREDO	0.631	0.144	0.631	0.001
Rv2231c.1	2	3mss_STI_D_1 PDB CREDO	0.631	0.144	0.631	0.001
Rv2231c.1	2	3mss_STI_C_1 PDB CREDO	0.631	0.144	0.631	0.001
Rv2231c.1	2	3k5v_STI_B_2 PDB CREDO	0.630	0.145	0.630	0.001
Rv2231c.1	2	2hyy_STI_A_600 PDB CREDO	0.629	0.146	0.629	0.001
Rv2231c.1	2	3ms9_STI_A_1 PDB CREDO	0.629	0.146	0.629	0.001
Rv2231c.1	2	1iep_STI_A_201 PDB CREDO	0.625	0.150	0.625	0.001
Rv2231c.1	2	2hyy_STI_C_600 PDB CREDO	0.625	0.150	0.625	0.001
Rv2231c.1	2	3oez_STI_A_601 PDB CREDO	0.625	0.151	0.625	0.001
Rv2231c.1	2	1uwj_BAX_B_1723 PDB CREDO	0.660	0.115	0.623	0.001
Rv2231c.1	3	3bjw_SVR_E_503 PDB CREDO	0.635	0.140	0.618	0.001
Rv2231c.1	2	3cs9_NIL_A_600 PDB CREDO	0.670	0.106	0.616	0.002
Rv2231c.1	3	3b0w_DGX_B_1 PDB CREDO	0.650	0.124	0.615	0.002
Rv2231c.1	3	1uwj_BAX_A_1723 PDB CREDO	0.666	0.110	0.612	0.002
Rv2231c.1	2	1opj_STI_A_3 PDB CREDO	0.665	0.111	0.611	0.002
Rv2231c.1	2	4asd_BAX_A_1500 PDB CREDO	0.647	0.128	0.610	0.002
Rv2231c.1	2	3k5v_STI_A_2 PDB CREDO	0.645	0.129	0.610	0.002
Rv2231c.1	2	2oiq_STI_A_1001 PDB CREDO	0.665	0.110	0.609	0.002
Rv2231c.1	2	2hyy_STI_B_600 PDB CREDO	0.665	0.110	0.609	0.002
Rv2231c.1	2	1opj_STI_B_4 PDB CREDO	0.660	0.115	0.607	0.002
Rv2231c.1	2	3cs9_NIL_B_600 PDB CREDO	0.677	0.099	0.606	0.002
Rv2231c.1	3	3sm2_478_A_126 PDB CREDO	0.708	0.075	0.605	0.002
Rv2231c.1	1	1lhv_NOG_A_301 PDB CREDO	0.624	0.151	0.604	0.002
Rv2231c.1	1	1p93_DEX_D_4999 PDB CREDO	0.604	0.174	0.604	0.002
Rv2231c.1	1	3bbt_FMM_D_91 PDB CREDO	0.667	0.108	0.604	0.002
Rv2231c.1	2	1uwh_BAX_A_1723 PDB CREDO	0.676	0.100	0.601	0.002
Rv2231c.1	2	1uwh_BAX_B_1723 PDB CREDO	0.676	0.100	0.600	0.002
Rv2231c.1	3	3h52_486_B_1 PDB CREDO	0.733	0.058	0.600	0.002
Rv2231c.1	1	3mne_DEX_A_784 PDB CREDO	0.600	0.179	0.600	0.002
Rv2231c.1	12	3sm2_478_A_126 PDB CREDO	0.775	0.035	0.598	0.002
Rv2231c.1	1	3gn8_DEX_B_247 PDB CREDO	0.598	0.182	0.598	0.002
Rv2231c.1	2	3b0w_DGX_B_1 PDB CREDO	0.631	0.144	0.596	0.002
Rv2231c.1	3	3h52_486_D_2 PDB CREDO	0.747	0.049	0.593	0.002
Rv2231c.1	1	1p93_DEX_C_3999 PDB CREDO	0.593	0.187	0.593	0.002
Rv2231c.1	1	1uwh_BAX_B_1723 PDB CREDO	0.672	0.104	0.592	0.002
Rv2231c.1	3	3cs9_NIL_A_600 PDB CREDO	0.608	0.169	0.592	0.002
Rv2231c.1	1	1uwh_BAX_A_1723 PDB CREDO	0.671	0.105	0.592	0.002
Rv2231c.1	3	3gp0_NIL_A_1 PDB CREDO	0.640	0.135	0.591	0.002
Rv2231c.1	2	3heg_BAX_A_1 PDB CREDO	0.645	0.129	0.590	0.003
Rv2231c.1	3	3cs9_NIL_B_600 PDB CREDO	0.590	0.191	0.590	0.003
Rv2231c.1	1	3gn8_DEX_A_247 PDB CREDO	0.590	0.192	0.590	0.003
Rv2231c.1	1	1nhz_486_A_800 PDB CREDO	0.628	0.147	0.588	0.003
Rv2231c.1	2	3gcs_BAX_A_401 PDB CREDO	0.623	0.153	0.588	0.003
Rv2231c.1	3	3h52_486_A_3 PDB CREDO	0.739	0.054	0.587	0.003
Rv2231c.1	1	1z2b_VLB_C_800 PDB CREDO	0.686	0.091	0.587	0.003
Rv2231c.1	1	1m2z_DEX_A_301 PDB CREDO	0.587	0.195	0.587	0.003
Rv2231c.1	1	1m2z_DEX_D_401 PDB CREDO	0.586	0.196	0.586	0.003
Rv2231c.1	2	1y0x_T44_X_500 PDB CREDO	0.660	0.115	0.586	0.003
Rv2231c.1	2	3cs9_NIL_C_600 PDB CREDO	0.690	0.088	0.585	0.003
Rv2231c.1	2	2pl0_STI_A_200 PDB CREDO	0.637	0.138	0.583	0.003
Rv2231c.1	3	2xkw_P1B_A_1478 PDB CREDO	0.665	0.111	0.583	0.003
Rv2231c.1	1	2aa6_STR_A_401 PDB CREDO	0.601	0.178	0.581	0.003
Rv2231c.1	1	3d91_REM_B_350 PDB CREDO	0.699	0.081	0.580	0.003
Rv2231c.1	12	1xkk_FMM_A_91 PDB CREDO	0.791	0.028	0.580	0.003
Rv2231c.1	3	1sa1_POD_B_700 PDB CREDO	0.688	0.090	0.580	0.003
Rv2231c.1	3	3frq_ERY_A_195 PDB CREDO	0.668	0.107	0.580	0.003
Rv2231c.1	3	3kk6_CEL_B_1701 PDB CREDO	0.580	0.204	0.580	0.003
Rv2231c.1	2	2qxs_RAL_A_600 PDB CREDO	0.648	0.126	0.580	0.003
Rv2231c.1	1	2aax_PDN_B_503 PDB CREDO	0.599	0.180	0.580	0.003
Rv2231c.1	1	3d91_REM_A_350 PDB CREDO	0.698	0.083	0.579	0.003
Rv2231c.1	1	1a28_STR_B_2 PDB CREDO	0.597	0.183	0.578	0.003
Rv2231c.1	2	2qxs_RAL_B_600 PDB CREDO	0.646	0.129	0.577	0.003
Rv2231c.1	1	2aa6_STR_B_402 PDB CREDO	0.596	0.184	0.577	0.003
Rv2231c.1	2	3cs9_NIL_D_600 PDB CREDO	0.680	0.097	0.576	0.003
Rv2231c.1	1	2aax_PDN_A_502 PDB CREDO	0.596	0.184	0.576	0.003
Rv2231c.1	3	3spk_TPV_B_100 PDB CREDO	0.663	0.112	0.576	0.003
Rv2231c.1	3	3bjw_SVR_B_501 PDB CREDO	0.640	0.135	0.575	0.003
Rv2231c.1	1	2x9g_LYA_A_1270 PDB CREDO	0.594	0.186	0.575	0.003
Rv2231c.1	3	1opj_STI_A_3 PDB CREDO	0.591	0.190	0.575	0.003
Rv2231c.1	2	1t46_STI_A_3 PDB CREDO	0.678	0.099	0.574	0.003
Rv2231c.1	3	1skx_RFP_A_1 PDB CREDO	0.574	0.212	0.574	0.003
Rv2231c.1	3	3bjw_SVR_H_504 PDB CREDO	0.637	0.137	0.573	0.003
Rv2231c.1	2	1err_RAL_A_600 PDB CREDO	0.665	0.110	0.573	0.003
Rv2231c.1	1	2gqg_1N1_B_502 PDB CREDO	0.592	0.189	0.573	0.003
Rv2231c.1	3	3bjw_SVR_F_502 PDB CREDO	0.636	0.138	0.572	0.003
Rv2231c.1	1	3tne_RIT_A_401 PDB CREDO	0.610	0.167	0.572	0.003
Rv2231c.1	2	3d91_REM_B_350 PDB CREDO	0.605	0.173	0.571	0.004
Rv2231c.1	3	1opj_STI_B_4 PDB CREDO	0.587	0.195	0.571	0.004
Rv2231c.1	1	2hw2_RFP_A_1200 PDB CREDO	0.608	0.169	0.570	0.004
Rv2231c.1	2	3oez_STI_B_601 PDB CREDO	0.682	0.095	0.569	0.004
Rv2231c.1	2	2jfa_RAL_B_600 PDB CREDO	0.661	0.114	0.569	0.004
Rv2231c.1	2	3b0w_DGX_A_1 PDB CREDO	0.603	0.175	0.569	0.004
Rv2231c.1	1	1zgy_BRL_A_503 PDB CREDO	0.607	0.170	0.568	0.004
Rv2231c.1	1	1fm6_BRL_X_504 PDB CREDO	0.586	0.196	0.568	0.004
Rv2231c.1	3	3cs9_NIL_D_600 PDB CREDO	0.599	0.180	0.568	0.004
Rv2231c.1	3	3cs9_NIL_C_600 PDB CREDO	0.599	0.181	0.567	0.004
Rv2231c.1	1	2h42_VIA_A_901 PDB CREDO	0.627	0.149	0.567	0.004
Rv2231c.1	3	1uwj_BAX_B_1723 PDB CREDO	0.672	0.104	0.567	0.004
Rv2231c.1	2	1err_RAL_B_600 PDB CREDO	0.657	0.117	0.566	0.004
Rv2231c.1	1	1qkn_RAL_A_600 PDB CREDO	0.565	0.223	0.565	0.004
Rv2231c.1	1	2aa5_STR_B_302 PDB CREDO	0.584	0.198	0.565	0.004
Rv2231c.1	1	2y6o_1N1_A_1892 PDB CREDO	0.584	0.199	0.565	0.004
Rv2231c.1	2	3d91_REM_A_350 PDB CREDO	0.599	0.180	0.565	0.004
Rv2231c.1	3	1n49_RIT_B_301 PDB CREDO	0.581	0.203	0.565	0.004
Rv2231c.1	3	1sa1_POD_D_701 PDB CREDO	0.690	0.088	0.565	0.004
Rv2231c.1	1	3jwq_VIA_D_901 PDB CREDO	0.624	0.151	0.565	0.004
Rv2231c.1	3	1z2b_VLB_C_800 PDB CREDO	0.690	0.089	0.565	0.004
Rv2231c.1	2	2hw2_RFP_A_1200 PDB CREDO	0.676	0.100	0.564	0.004
Rv2231c.1	2	2w8y_486_A_1000 PDB CREDO	0.598	0.181	0.564	0.004
Rv2231c.1	1	1p93_DEX_B_2999 PDB CREDO	0.622	0.153	0.563	0.004
Rv2231c.1	1	2aa5_STR_A_301 PDB CREDO	0.582	0.201	0.563	0.004
Rv2231c.1	1	1mx1_THA_C_3 PDB CREDO	0.667	0.109	0.563	0.004
Rv2231c.1	3	2oax_SNL_F_6001 PDB CREDO	0.687	0.091	0.562	0.004
Rv2231c.1	1	3h0a_9RA_A_500 PDB CREDO	0.621	0.154	0.562	0.004
Rv2231c.1	3	2oax_SNL_D_4001 PDB CREDO	0.686	0.092	0.562	0.004
Rv2231c.1	3	2oax_SNL_A_1001 PDB CREDO	0.686	0.092	0.561	0.004
Rv2231c.1	1	3mnp_DEX_A_784 PDB CREDO	0.617	0.159	0.561	0.004
Rv2231c.1	3	3oez_STI_A_601 PDB CREDO	0.627	0.148	0.561	0.004
Rv2231c.1	1	1p93_DEX_A_1999 PDB CREDO	0.619	0.157	0.560	0.004
Rv2231c.1	1	2ab2_SNL_A_502 PDB CREDO	0.597	0.183	0.560	0.004
Rv2231c.1	1	2ab2_SNL_B_503 PDB CREDO	0.597	0.183	0.560	0.004
Rv2231c.1	1	3h52_486_D_2 PDB CREDO	0.635	0.140	0.560	0.004
Rv2231c.1	2	3uvv_T3_A_501 PDB CREDO	0.692	0.087	0.560	0.004
Rv2231c.1	2	1xzx_T3_X_500 PDB CREDO	0.692	0.087	0.559	0.004
Rv2231c.1	3	3b0w_DGX_A_1 PDB CREDO	0.662	0.113	0.559	0.004
Rv2231c.1	3	3ufn_ROC_A_401 PDB CREDO	0.605	0.173	0.558	0.004
Rv2231c.1	12	1ya4_CTX_A_1 PDB CREDO	0.671	0.105	0.558	0.004
Rv2231c.1	3	2oax_SNL_E_5001 PDB CREDO	0.681	0.096	0.557	0.004
Rv2231c.1	1	3mno_DEX_A_784 PDB CREDO	0.612	0.164	0.557	0.004
Rv2231c.1	1	1uwj_BAX_B_1723 PDB CREDO	0.670	0.106	0.556	0.005
Rv2231c.1	3	3kk6_CEL_A_701 PDB CREDO	0.618	0.158	0.556	0.005
Rv2231c.1	3	1n49_RIT_D_401 PDB CREDO	0.621	0.155	0.555	0.005
Rv2231c.1	1	3h52_486_A_3 PDB CREDO	0.629	0.146	0.555	0.005
Rv2231c.1	3	4asd_BAX_A_1500 PDB CREDO	0.658	0.117	0.555	0.005
Rv2231c.1	1	2w8y_486_A_1000 PDB CREDO	0.668	0.108	0.554	0.005
Rv2231c.1	3	1uwh_BAX_B_1723 PDB CREDO	0.698	0.082	0.554	0.005
Rv2231c.1	3	2w8y_486_A_1000 PDB CREDO	0.657	0.118	0.554	0.005
Rv2231c.1	1	3h52_486_B_1 PDB CREDO	0.648	0.127	0.554	0.005
Rv2231c.1	3	1uwh_BAX_A_1723 PDB CREDO	0.697	0.083	0.553	0.005
Rv2231c.1	1	3k54_1N1_A_1 PDB CREDO	0.703	0.078	0.552	0.005
Rv2231c.1	3	2nni_MTK_A_501 PDB CREDO	0.636	0.139	0.552	0.005
Rv2231c.1	3	3d91_REM_B_350 PDB CREDO	0.655	0.120	0.552	0.005
Rv2231c.1	2	3gws_T3_X_500 PDB CREDO	0.705	0.077	0.552	0.005
Rv2231c.1	1	3oct_1N1_A_663 PDB CREDO	0.630	0.145	0.551	0.005
Rv2231c.1	12	2xkw_P1B_A_1478 PDB CREDO	0.732	0.059	0.551	0.005
Rv2231c.1	1	2q1v_PDN_A_248 PDB CREDO	0.629	0.146	0.550	0.005
Rv2231c.1	3	3k5v_STI_A_2 PDB CREDO	0.581	0.202	0.550	0.005
Rv2231c.1	1	2oax_SNL_C_3001 PDB CREDO	0.586	0.196	0.550	0.005
Rv2231c.1	2	1fm6_BRL_X_504 PDB CREDO	0.679	0.097	0.549	0.005
Rv2231c.1	2	2jfa_RAL_A_600 PDB CREDO	0.657	0.117	0.549	0.005
Rv2231c.1	1	2oax_SNL_B_2001 PDB CREDO	0.585	0.198	0.549	0.005
Rv2231c.1	3	3frq_ERY_B_195 PDB CREDO	0.735	0.057	0.548	0.005
Rv2231c.1	2	1qkn_RAL_A_600 PDB CREDO	0.700	0.081	0.548	0.005
Rv2231c.1	1	1lhu_EST_A_301 PDB CREDO	0.649	0.125	0.548	0.005
Rv2231c.1	1	3vhu_SNL_A_1001 PDB CREDO	0.584	0.199	0.548	0.005
Rv2231c.1	2	2xkw_P1B_A_1478 PDB CREDO	0.699	0.082	0.548	0.005
Rv2231c.1	3	2v0z_C41_O_1327 PDB CREDO	0.593	0.187	0.548	0.005
Rv2231c.1	3	2oiq_STI_A_1001 PDB CREDO	0.668	0.107	0.547	0.005
Rv2231c.1	1	3d90_NOG_A_1001 PDB CREDO	0.584	0.198	0.547	0.005
Rv2231c.1	3	3d91_REM_A_350 PDB CREDO	0.647	0.128	0.545	0.005
Rv2231c.1	1	2h42_VIA_C_903 PDB CREDO	0.669	0.106	0.545	0.005
Rv2231c.1	3	2hyy_STI_A_600 PDB CREDO	0.610	0.168	0.545	0.005
Rv2231c.1	3	3pyy_STI_A_3 PDB CREDO	0.610	0.168	0.545	0.005
Rv2231c.1	1	2x9g_LYA_B_1270 PDB CREDO	0.581	0.202	0.544	0.006
Rv2231c.1	2	1bsx_T3_A_1 PDB CREDO	0.694	0.085	0.544	0.006
Rv2231c.1	2	1bsx_T3_B_2 PDB CREDO	0.694	0.085	0.544	0.006
Rv2231c.1	2	1uob_PNN_A_1311 PDB CREDO	0.594	0.186	0.544	0.006
Rv2231c.1	2	3h52_486_D_2 PDB CREDO	0.612	0.165	0.544	0.006
Rv2231c.1	2	1skx_RFP_A_1 PDB CREDO	0.608	0.170	0.544	0.006
Rv2231c.1	3	3mss_STI_C_1 PDB CREDO	0.607	0.170	0.543	0.006
Rv2231c.1	3	1iep_STI_A_201 PDB CREDO	0.607	0.171	0.543	0.006
Rv2231c.1	3	2hw2_RFP_A_1200 PDB CREDO	0.727	0.061	0.543	0.006
Rv2231c.1	3	3mss_STI_A_1 PDB CREDO	0.607	0.171	0.543	0.006
Rv2231c.1	3	1iep_STI_B_202 PDB CREDO	0.606	0.172	0.542	0.006
Rv2231c.1	3	3ms9_STI_A_1 PDB CREDO	0.606	0.172	0.542	0.006
Rv2231c.1	3	2hyy_STI_C_600 PDB CREDO	0.606	0.172	0.542	0.006
Rv2231c.1	2	3h52_486_B_1 PDB CREDO	0.592	0.189	0.542	0.006
Rv2231c.1	1	2h42_VIA_B_902 PDB CREDO	0.665	0.110	0.542	0.006
Rv2231c.1	12	3oxc_ROC_A_401 PDB CREDO	0.565	0.223	0.541	0.006
Rv2231c.1	1	1ya3_STR_A_1001 PDB CREDO	0.619	0.157	0.541	0.006
Rv2231c.1	1	2gqg_1N1_A_501 PDB CREDO	0.664	0.111	0.541	0.006
Rv2231c.1	3	3k5v_STI_B_2 PDB CREDO	0.605	0.173	0.541	0.006
Rv2231c.1	3	3ms9_STI_B_1 PDB CREDO	0.605	0.173	0.541	0.006
Rv2231c.1	3	3pyy_STI_B_4 PDB CREDO	0.605	0.174	0.541	0.006
Rv2231c.1	2	1xkk_FMM_A_91 PDB CREDO	0.672	0.104	0.540	0.006
Rv2231c.1	1	1ya3_STR_B_2001 PDB CREDO	0.618	0.158	0.540	0.006
Rv2231c.1	3	3mss_STI_D_1 PDB CREDO	0.604	0.174	0.540	0.006
Rv2231c.1	1	1jg2_ADN_A_500 PDB CREDO	0.618	0.158	0.540	0.006
Rv2231c.1	3	3mss_STI_B_1 PDB CREDO	0.604	0.175	0.540	0.006
Rv2231c.1	2	1z2b_VLB_C_800 PDB CREDO	0.589	0.193	0.539	0.006
Rv2231c.1	12	3gp0_NIL_A_1 PDB CREDO	0.754	0.045	0.539	0.006
Rv2231c.1	1	3ln1_CEL_A_682 PDB CREDO	0.539	0.260	0.539	0.006
Rv2231c.1	1	3ln1_CEL_B_682 PDB CREDO	0.539	0.260	0.539	0.006
Rv2231c.1	2	3vn2_TLS_A_501 PDB CREDO	0.625	0.150	0.539	0.006
Rv2231c.1	1	3vn2_TLS_A_501 PDB CREDO	0.592	0.188	0.538	0.006
Rv2231c.1	2	3rgf_BAX_A_465 PDB CREDO	0.554	0.238	0.538	0.006
Rv2231c.1	2	2y6o_1N1_A_1892 PDB CREDO	0.666	0.110	0.538	0.006
Rv2231c.1	1	3frq_ERY_B_195 PDB CREDO	0.574	0.212	0.538	0.006
Rv2231c.1	3	2hyy_STI_D_600 PDB CREDO	0.602	0.177	0.538	0.006
Rv2231c.1	1	3d90_NOG_B_2001 PDB CREDO	0.574	0.211	0.537	0.006
Rv2231c.1	1	3ln1_CEL_C_682 PDB CREDO	0.537	0.262	0.537	0.006
Rv2231c.1	3	1y0x_T44_X_500 PDB CREDO	0.676	0.100	0.537	0.006
Rv2231c.1	3	3gvu_STI_A_1001 PDB CREDO	0.601	0.178	0.537	0.006
Rv2231c.1	3	2ab2_SNL_A_502 PDB CREDO	0.719	0.067	0.537	0.006
Rv2231c.1	2	3bjw_SVR_E_503 PDB CREDO	0.617	0.160	0.537	0.006
Rv2231c.1	2	3ln1_CEL_C_682 PDB CREDO	0.685	0.093	0.536	0.006
Rv2231c.1	1	2jfa_RAL_A_600 PDB CREDO	0.572	0.215	0.536	0.006
Rv2231c.1	3	2jfa_RAL_B_600 PDB CREDO	0.696	0.084	0.536	0.006
Rv2231c.1	3	1err_RAL_A_600 PDB CREDO	0.695	0.085	0.535	0.006
Rv2231c.1	3	2ab2_SNL_B_503 PDB CREDO	0.717	0.068	0.535	0.006
Rv2231c.1	1	1bsx_T3_A_1 PDB CREDO	0.535	0.265	0.535	0.006
Rv2231c.1	1	1bsx_T3_B_2 PDB CREDO	0.535	0.265	0.535	0.006
Rv2231c.1	1	3gws_T3_X_500 PDB CREDO	0.535	0.265	0.535	0.006
Rv2231c.1	1	2oax_SNL_F_6001 PDB CREDO	0.626	0.150	0.535	0.006
Rv2231c.1	1	1uwj_BAX_A_1723 PDB CREDO	0.703	0.079	0.535	0.006
Rv2231c.1	3	3mnp_DEX_A_784 PDB CREDO	0.694	0.085	0.535	0.006
Rv2231c.1	2	3ln1_CEL_B_682 PDB CREDO	0.683	0.095	0.535	0.006
Rv2231c.1	3	1err_RAL_B_600 PDB CREDO	0.694	0.086	0.534	0.006
Rv2231c.1	3	3mno_DEX_A_784 PDB CREDO	0.694	0.086	0.534	0.006
Rv2231c.1	1	1mx1_THA_E_5 PDB CREDO	0.680	0.097	0.534	0.006
Rv2231c.1	3	3el9_DR7_A_100 PDB CREDO	0.548	0.246	0.534	0.007
Rv2231c.1	2	3gp0_NIL_A_1 PDB CREDO	0.646	0.128	0.533	0.007
Rv2231c.1	2	3ln1_CEL_A_682 PDB CREDO	0.681	0.096	0.533	0.007
Rv2231c.1	2	3kk6_CEL_B_1701 PDB CREDO	0.596	0.184	0.533	0.007
Rv2231c.1	3	2oax_SNL_B_2001 PDB CREDO	0.713	0.071	0.532	0.007
Rv2231c.1	1	2oax_SNL_E_5001 PDB CREDO	0.622	0.154	0.532	0.007
Rv2231c.1	1	3spk_TPV_A_100 PDB CREDO	0.568	0.220	0.531	0.007
Rv2231c.1	1	2oax_SNL_D_4001 PDB CREDO	0.621	0.154	0.531	0.007
Rv2231c.1	1	2jfa_RAL_B_600 PDB CREDO	0.584	0.198	0.531	0.007
Rv2231c.1	3	3e22_LOC_B_700 PDB CREDO	0.711	0.072	0.531	0.007
Rv2231c.1	3	1c6z_ROC_B_505 PDB CREDO	0.636	0.138	0.531	0.007
Rv2231c.1	3	3e22_LOC_D_700 PDB CREDO	0.711	0.073	0.531	0.007
Rv2231c.1	1	2prg_BRL_B_2 PDB CREDO	0.628	0.147	0.530	0.007
Rv2231c.1	1	3bbt_FMM_B_91 PDB CREDO	0.728	0.061	0.530	0.007
Rv2231c.1	3	2pym_1UN_A_1001 PDB CREDO	0.636	0.139	0.530	0.007
Rv2231c.1	1	2oax_SNL_A_1001 PDB CREDO	0.620	0.156	0.530	0.007
Rv2231c.1	3	2hyy_STI_B_600 PDB CREDO	0.647	0.127	0.530	0.007
Rv2231c.1	1	3tne_RIT_B_401 PDB CREDO	0.565	0.224	0.530	0.007
Rv2231c.1	12	1t46_STI_A_3 PDB CREDO	0.761	0.042	0.529	0.007
Rv2231c.1	1	3rif_IVM_D_402 PDB CREDO	0.650	0.124	0.529	0.007
Rv2231c.1	1	1fm6_BRL_D_503 PDB CREDO	0.627	0.149	0.529	0.007
Rv2231c.1	1	3ria_IVM_C_349 PDB CREDO	0.649	0.125	0.529	0.007
Rv2231c.1	1	3rif_IVM_A_402 PDB CREDO	0.649	0.125	0.529	0.007
Rv2231c.1	1	1err_RAL_A_600 PDB CREDO	0.581	0.202	0.528	0.007
Rv2231c.1	1	3oht_1N1_B_1000 PDB CREDO	0.626	0.149	0.528	0.007
Rv2231c.1	3	1xzx_T3_X_500 PDB CREDO	0.730	0.060	0.528	0.007
Rv2231c.1	3	3heg_BAX_A_1 PDB CREDO	0.645	0.129	0.528	0.007
Rv2231c.1	3	3uvv_T3_A_501 PDB CREDO	0.730	0.060	0.528	0.007
Rv2231c.1	1	2prg_BRL_A_1 PDB CREDO	0.625	0.150	0.528	0.007
Rv2231c.1	1	3rif_IVM_B_403 PDB CREDO	0.648	0.126	0.528	0.007
Rv2231c.1	2	2x9g_LYA_A_1270 PDB CREDO	0.652	0.122	0.528	0.007
Rv2231c.1	1	2fum_MIX_D_3539 PDB CREDO	0.583	0.200	0.527	0.007
Rv2231c.1	2	3nxu_RIT_A_600 PDB CREDO	0.590	0.192	0.527	0.007
Rv2231c.1	3	2oax_SNL_C_3001 PDB CREDO	0.706	0.076	0.527	0.007
Rv2231c.1	3	2q64_1UN_B_1001 PDB CREDO	0.632	0.142	0.527	0.007
Rv2231c.1	2	3h52_486_A_3 PDB CREDO	0.593	0.187	0.527	0.007
Rv2231c.1	1	1xzx_T3_X_500 PDB CREDO	0.544	0.252	0.527	0.007
Rv2231c.1	3	2qak_1UN_A_1001 PDB CREDO	0.632	0.143	0.527	0.007
Rv2231c.1	2	3nxu_RIT_B_600 PDB CREDO	0.589	0.192	0.527	0.007
Rv2231c.1	3	3gcs_BAX_A_401 PDB CREDO	0.625	0.151	0.527	0.007
Rv2231c.1	3	1c6y_MK1_B_524 PDB CREDO	0.541	0.257	0.526	0.007
Rv2231c.1	1	3tkd_CYZ_A_266 PDB CREDO	0.561	0.229	0.526	0.007
Rv2231c.1	1	3ri5_IVM_C_350 PDB CREDO	0.646	0.128	0.526	0.007
Rv2231c.1	3	2pl0_STI_A_200 PDB CREDO	0.642	0.132	0.526	0.007
Rv2231c.1	1	1a28_STR_A_1 PDB CREDO	0.623	0.153	0.526	0.007
Rv2231c.1	12	3bjw_SVR_B_501 PDB CREDO	0.716	0.069	0.525	0.007
Rv2231c.1	12	3el4_ROC_A_100 PDB CREDO	0.602	0.176	0.525	0.007
Rv2231c.1	1	3b0w_DGX_A_1 PDB CREDO	0.632	0.142	0.525	0.007
Rv2231c.1	2	3sm2_478_A_126 PDB CREDO	0.687	0.091	0.525	0.007
Rv2231c.1	2	3spk_TPV_B_100 PDB CREDO	0.540	0.258	0.525	0.007
Rv2231c.1	1	3h52_486_C_4 PDB CREDO	0.644	0.131	0.524	0.008
Rv2231c.1	1	4eb6_VLB_C_503 PDB CREDO	0.644	0.131	0.524	0.008
Rv2231c.1	1	1err_RAL_B_600 PDB CREDO	0.576	0.209	0.524	0.008
Rv2231c.1	3	3vhu_SNL_A_1001 PDB CREDO	0.701	0.080	0.524	0.008
Rv2231c.1	3	2q63_1UN_A_1001 PDB CREDO	0.628	0.147	0.523	0.008
Rv2231c.1	2	3hec_STI_A_1 PDB CREDO	0.627	0.148	0.523	0.008
Rv2231c.1	12	2nmy_ROC_A_401 PDB CREDO	0.547	0.248	0.523	0.008
Rv2231c.1	12	2q64_1UN_B_1001 PDB CREDO	0.661	0.114	0.523	0.008
Rv2231c.1	1	4asd_BAX_A_1500 PDB CREDO	0.630	0.145	0.523	0.008
Rv2231c.1	3	1hwk_117_B_1 PDB CREDO	0.585	0.198	0.523	0.008
Rv2231c.1	3	3ut5_LOC_D_502 PDB CREDO	0.700	0.080	0.523	0.008
Rv2231c.1	12	2qak_1UN_A_1001 PDB CREDO	0.660	0.114	0.523	0.008
Rv2231c.1	2	2h77_T3_A_1 PDB CREDO	0.713	0.071	0.523	0.008
Rv2231c.1	3	2pyn_1UN_A_1001 PDB CREDO	0.627	0.148	0.523	0.008
Rv2231c.1	2	2h79_T3_A_1 PDB CREDO	0.689	0.089	0.522	0.008
Rv2231c.1	12	2pym_1UN_A_1001 PDB CREDO	0.660	0.115	0.522	0.008
Rv2231c.1	1	1sqn_NDR_A_1001 PDB CREDO	0.618	0.158	0.522	0.008
Rv2231c.1	1	1sqn_NDR_B_2001 PDB CREDO	0.618	0.158	0.521	0.008
Rv2231c.1	1	3rif_IVM_A_403 PDB CREDO	0.640	0.134	0.521	0.008
Rv2231c.1	12	2pyn_1UN_A_1001 PDB CREDO	0.659	0.116	0.521	0.008
Rv2231c.1	1	3tkd_CYZ_B_267 PDB CREDO	0.591	0.190	0.521	0.008
Rv2231c.1	1	3uvv_T3_A_501 PDB CREDO	0.537	0.262	0.520	0.008
Rv2231c.1	3	3ut5_LOC_B_502 PDB CREDO	0.655	0.120	0.520	0.008
Rv2231c.1	12	2q63_1UN_A_1001 PDB CREDO	0.657	0.117	0.520	0.008
Rv2231c.1	3	1bsx_T3_A_1 PDB CREDO	0.742	0.052	0.520	0.008
Rv2231c.1	3	1bsx_T3_B_2 PDB CREDO	0.742	0.052	0.520	0.008
Rv2231c.1	3	1a28_STR_B_2 PDB CREDO	0.718	0.067	0.519	0.008
Rv2231c.1	3	3gws_T3_X_500 PDB CREDO	0.741	0.053	0.519	0.008
Rv2231c.1	12	3bjw_SVR_H_504 PDB CREDO	0.707	0.075	0.518	0.008
Rv2231c.1	3	1lhv_NOG_A_301 PDB CREDO	0.717	0.069	0.518	0.008
Rv2231c.1	1	1s9p_DES_A_459 PDB CREDO	0.614	0.163	0.518	0.008
Rv2231c.1	12	3k4v_ROC_B_201 PDB CREDO	0.576	0.209	0.518	0.008
Rv2231c.1	12	3ndu_ROC_D_100 PDB CREDO	0.553	0.239	0.517	0.008
Rv2231c.1	1	3jwq_VIA_B_901 PDB CREDO	0.635	0.140	0.517	0.008
Rv2231c.1	1	3ln1_CEL_D_682 PDB CREDO	0.572	0.215	0.517	0.008
Rv2231c.1	3	3nxu_RIT_A_600 PDB CREDO	0.517	0.292	0.517	0.008
Rv2231c.1	3	3nxu_RIT_B_600 PDB CREDO	0.516	0.293	0.516	0.008
Rv2231c.1	3	2v0z_C41_C_1328 PDB CREDO	0.604	0.174	0.516	0.009
Rv2231c.1	3	2y6o_1N1_A_1892 PDB CREDO	0.714	0.071	0.516	0.009
Rv2231c.1	1	2pl0_STI_A_200 PDB CREDO	0.603	0.175	0.516	0.009
Rv2231c.1	3	1uob_PNN_A_1311 PDB CREDO	0.630	0.145	0.516	0.009
Rv2231c.1	1	1jg3_ADN_A_500 PDB CREDO	0.657	0.118	0.516	0.009
Rv2231c.1	12	3bjw_SVR_F_502 PDB CREDO	0.702	0.080	0.515	0.009
Rv2231c.1	3	3tkd_CYZ_B_267 PDB CREDO	0.648	0.127	0.514	0.009
Rv2231c.1	12	2qxs_RAL_B_600 PDB CREDO	0.779	0.033	0.514	0.009
Rv2231c.1	1	1gs4_ZK5_A_1918 PDB CREDO	0.631	0.144	0.513	0.009
Rv2231c.1	1	3ads_IMN_A_2 PDB CREDO	0.587	0.194	0.513	0.009
Rv2231c.1	1	3q70_RIT_A_2001 PDB CREDO	0.600	0.179	0.513	0.009
Rv2231c.1	12	2qxs_RAL_A_600 PDB CREDO	0.777	0.034	0.513	0.009
Rv2231c.1	3	2fxd_DR7_A_102 PDB CREDO	0.527	0.277	0.513	0.009
Rv2231c.1	3	3bbt_FMM_D_91 PDB CREDO	0.809	0.022	0.512	0.009
Rv2231c.1	3	3vn2_TLS_A_501 PDB CREDO	0.665	0.110	0.512	0.009
Rv2231c.1	3	1fm6_BRL_X_504 PDB CREDO	0.708	0.075	0.512	0.009
Rv2231c.1	12	3k4v_ROC_D_201 PDB CREDO	0.573	0.213	0.512	0.009
Rv2231c.1	12	3cs9_NIL_C_600 PDB CREDO	0.735	0.057	0.511	0.009
Rv2231c.1	3	2jfa_RAL_A_600 PDB CREDO	0.685	0.093	0.511	0.009
Rv2231c.1	3	3gn8_DEX_B_247 PDB CREDO	0.730	0.060	0.511	0.009
Rv2231c.1	12	3cs9_NIL_D_600 PDB CREDO	0.734	0.057	0.511	0.009
Rv2231c.1	2	3tne_RIT_A_401 PDB CREDO	0.612	0.165	0.511	0.009
Rv2231c.1	1	3oez_STI_B_601 PDB CREDO	0.544	0.252	0.510	0.009
Rv2231c.1	1	3qt0_486_A_4 PDB CREDO	0.564	0.225	0.510	0.009
Rv2231c.1	3	3gn8_DEX_A_247 PDB CREDO	0.729	0.060	0.510	0.009
Rv2231c.1	3	3lzv_017_A_200 PDB CREDO	0.539	0.259	0.510	0.009
Rv2231c.1	2	3bjw_SVR_B_501 PDB CREDO	0.634	0.140	0.510	0.009
Rv2231c.1	2	3h0a_9RA_A_500 PDB CREDO	0.720	0.066	0.510	0.009
Rv2231c.1	3	3jwq_VIA_D_901 PDB CREDO	0.805	0.023	0.510	0.009
Rv2231c.1	12	3ndt_ROC_A_101 PDB CREDO	0.579	0.204	0.510	0.009
Rv2231c.1	12	1k6c_MK1_B_902 PDB CREDO	0.585	0.198	0.510	0.009
Rv2231c.1	2	3bjw_SVR_H_504 PDB CREDO	0.634	0.141	0.509	0.009
Rv2231c.1	2	3ln1_CEL_D_682 PDB CREDO	0.719	0.067	0.509	0.009
Rv2231c.1	3	1ya4_CTX_A_1 PDB CREDO	0.642	0.133	0.509	0.009
Rv2231c.1	2	1a28_STR_B_2 PDB CREDO	0.629	0.146	0.509	0.010
Rv2231c.1	3	3ekq_ROC_A_100 PDB CREDO	0.509	0.305	0.509	0.010
Rv2231c.1	3	3oez_STI_B_601 PDB CREDO	0.682	0.096	0.509	0.010
Rv2231c.1	12	1c6z_ROC_B_505 PDB CREDO	0.643	0.132	0.509	0.010
Rv2231c.1	2	1zgy_BRL_A_503 PDB CREDO	0.694	0.086	0.508	0.010
Rv2231c.1	2	2oax_SNL_D_4001 PDB CREDO	0.555	0.236	0.508	0.010
Rv2231c.1	3	1p93_DEX_D_4999 PDB CREDO	0.726	0.062	0.508	0.010
Rv2231c.1	2	2oax_SNL_E_5001 PDB CREDO	0.555	0.237	0.508	0.010
Rv2231c.1	3	2aax_PDN_B_503 PDB CREDO	0.750	0.048	0.508	0.010
Rv2231c.1	3	3mne_DEX_A_784 PDB CREDO	0.726	0.063	0.508	0.010
Rv2231c.1	2	2oax_SNL_F_6001 PDB CREDO	0.554	0.238	0.508	0.010
Rv2231c.1	3	1m2z_DEX_D_401 PDB CREDO	0.725	0.063	0.508	0.010
Rv2231c.1	12	3bjw_SVR_E_503 PDB CREDO	0.749	0.048	0.507	0.010
Rv2231c.1	2	3frq_ERY_A_195 PDB CREDO	0.522	0.284	0.507	0.010
Rv2231c.1	2	3bjw_SVR_F_502 PDB CREDO	0.631	0.144	0.507	0.010
Rv2231c.1	1	1ya3_STR_C_3001 PDB CREDO	0.646	0.129	0.507	0.010
Rv2231c.1	3	1p93_DEX_C_3999 PDB CREDO	0.724	0.064	0.507	0.010
Rv2231c.1	1	2x9g_LYA_D_1270 PDB CREDO	0.580	0.204	0.507	0.010
Rv2231c.1	3	2aa6_STR_A_401 PDB CREDO	0.747	0.050	0.506	0.010
Rv2231c.1	1	2hyy_STI_B_600 PDB CREDO	0.592	0.189	0.506	0.010
Rv2231c.1	1	2h79_T3_A_1 PDB CREDO	0.523	0.283	0.506	0.010
Rv2231c.1	1	2x9g_LYA_C_1270 PDB CREDO	0.578	0.207	0.505	0.010
Rv2231c.1	1	3nrr_D16_B_520 PDB CREDO	0.578	0.207	0.505	0.010
Rv2231c.1	3	2aax_PDN_A_502 PDB CREDO	0.745	0.050	0.505	0.010
Rv2231c.1	2	3mnp_DEX_A_784 PDB CREDO	0.586	0.196	0.505	0.010
Rv2231c.1	3	2aa6_STR_B_402 PDB CREDO	0.745	0.051	0.505	0.010
Rv2231c.1	3	2h42_VIA_A_901 PDB CREDO	0.797	0.026	0.505	0.010
Rv2231c.1	12	3ucb_017_A_201 PDB CREDO	0.592	0.189	0.504	0.010
Rv2231c.1	3	3el0_1UN_A_201 PDB CREDO	0.532	0.269	0.504	0.010
Rv2231c.1	12	3ufn_ROC_A_401 PDB CREDO	0.704	0.077	0.503	0.010
Rv2231c.1	3	1m2z_DEX_A_301 PDB CREDO	0.719	0.067	0.503	0.010
Rv2231c.1	2	2oax_SNL_A_1001 PDB CREDO	0.549	0.245	0.503	0.010
Rv2231c.1	2	3mno_DEX_A_784 PDB CREDO	0.583	0.200	0.502	0.011
Rv2231c.1	2	3jwq_VIA_D_901 PDB CREDO	0.708	0.075	0.501	0.011
Rv2231c.1	1	2fum_MIX_A_539 PDB CREDO	0.616	0.161	0.501	0.011
Rv2231c.1	1	2h77_T3_A_1 PDB CREDO	0.536	0.265	0.501	0.011
Rv2231c.1	1	3sxr_1N1_A_1 PDB CREDO	0.744	0.051	0.501	0.011
Rv2231c.1	2	2gqg_1N1_B_502 PDB CREDO	0.661	0.114	0.501	0.011
Rv2231c.1	12	3cs9_NIL_B_600 PDB CREDO	0.759	0.043	0.501	0.011
Rv2231c.1	1	2oiq_STI_A_1001 PDB CREDO	0.585	0.197	0.501	0.011
Rv2231c.1	3	2h79_T3_A_1 PDB CREDO	0.738	0.055	0.500	0.011

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

Chemical Name	Confidence score	Molecular Weight
aminopropanolPubChem	0.923	75.1097
adenosylcobyric acidPubChem	0.92	1183.23
adenosylcobinamidePubChem	0.919	1240.32
adenosyl-cobyratePubChem	0.9	1182.22
2-(6-aminopurin-9-yl)-5-methanidyloxolane-3,4-diol; cobalt(3+); 3-[(1R,2S,3S,5Z,7S,8S,10Z,13S,15Z,17PubChem	0.9	1240.32
adenosyl-cobinamidePubChem	0.9	1240.32
hydroxyl radicalsPubChem	0.9	17.0073