Tuberculist information
Gene nameRv1540
Protein functionConserved hypothetical protein member of yabO/yceC/yfiI family
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)1742.84
Molecular mass(da)33016.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 308
	  		  	1    MADRSMPVPDGLAGMRVDTGLARLLGLSRTAAAALAEEGAVELNGVPAGKSDRLVSGALL   60
			  	61   QVRLPEAPAPLQNTPIDIEGMTILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAG  120
			  	121  YRITTSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPD  180
			  	181  PSSGTIDAPIGRHRGHEWKFAITKNGRHSLTHYDTLEAFVAASLLDVHLETGRTHQIRVH  240
			  	241  FAALHHPCCGDLVYGADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHA  300
			  	301  LKILRGEG
			  			

Known structures in the PDB
No Known structures
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
S4PF0147915-60
PseudoU_synth_2PF0084989-243
Mtb Structural Proteome models
Model Number1
Model nameRv1540
Template1V9F    APDBCREDO
Template coverage88_315
Template Identity(%)38.6
Model coverage(%)71.8
Normalized DOPE score-0.144

Model Number2
Model nameRv1540.1
Template1DM9    APDBCREDO
Template coverage8_49
Template Identity(%)29.3
Model coverage(%)12.9
Normalized DOPE score0.128

Structure Models from Chopin
Model Number1
Profiled.66.1.2
Click for model details
zscore9.28
Residue begin15
Residue end60
Model Number2
Profiled.265.1.3
Click for model details
zscore9.1
Residue begin86
Residue end275
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1540Gene nameConfidence Score
Rv1539lspA0.997
Rv3455ctruA0.971
Rv2793ctruB0.962
Rv2793ctruB0.962
Rv1711Rv17110.951
Rv1711Rv17110.951
Rv1538cansA0.944
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions