Rv1456c

Tuberculist information
Gene nameRv1456c
Protein functionProbable unidentified antibiotic-transport integral membrane ABC transporter
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1641.49
Molecular mass(da)32336.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 310
	  		  	1    VPYDRAVSPSLRVQRVIAAIVILTQGGIAVTGAIVRVTASGLGCPTWPQCFPGSFTPVVV   60
			  	61   AEVPRVHQAVEFGNRMVTFAVVIAAALAVLVVTRARRRTEVLAYAWLMPVSTVVQAMIGG  120
			  	121  ITVRTGLLWWTVAIHLLASMTMVWLAVLLYVKIGQPDDGVVHELVVSPLRALTALSALNL  180
			  	181  AAVLVTGTLVTAAGPHAGDRSPSRTVPRLKVEITTLVHMHSSLLVAYLALLIGLGFGLLA  240
			  	241  VGATRAILVRLAVLLALVATQAAVGTTQYFTGVPAALVAIHVAGAAAVTAATAALWASMG  300
			  	301  ERAQPQPLQR

Known structures in the PDB
No Known structures
1 32 63 94 125 156 187 218 249 280 311 Range: 15 to 293  |  Coverage: 89% COX15-CtaA Range: 11 to 277  |  Coverage: 85% 1
Number of amino acids : 310
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
COX15-CtaAPF0262815-293
Mtb Structural Proteome models
Model Number1
Model nameRv1456c
Template1L7V    APDBCREDO
Template coverage58_318
Template Identity(%)15.3
Model coverage(%)85.8
Normalized DOPE score1.179

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1456cGene nameConfidence Score
Rv1451ctaB0.993
Rv2200cctaC0.962
Rv2200cctaC0.962
Rv1458cRv1458c0.93
Rv1457cRv1457c0.928
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
heme OPubChem0.908838.854