Rv1451

Tuberculist information
Gene namectaB
Protein functionProbable cytochrome C oxidase assembly factor CtaB
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1635.03
Molecular mass(da)33506.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 308
	  		  	1    VNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTL   60
			  	61   VGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWC  120
			  	121  ATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPAL  180
			  	181  AMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVL  240
			  	241  ALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDS  300
			  	301  VIALPTLH

Known structures in the PDB
No Known structures
1 31 61 91 121 151 181 211 241 271 301 Range: 32 to 297  |  Coverage: 86% UbiA Range: 31 to 269  |  Coverage: 77% 1
Number of amino acids : 308
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UbiAPF0104032-297
Mtb Structural Proteome models
Model Number1
Model nameRv1451
Template1WPG    APDBCREDO
Template coverage764_989
Template Identity(%)8.4
Model coverage(%)77.3
Normalized DOPE score1.447

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1451Gene nameConfidence Score
Rv3043cctaD0.998
Rv2193ctaE0.998
Rv1456cRv1456c0.993
Rv2200cctaC0.982
Rv2200cctaC0.982
Rv1485hemZ0.97
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
heme OPubChem0.977838.854
hemePubChem0.969616.487
cetyltrimethylammonium bromidePubChem0.88284.543
heme aPubChem0.785852.837