Rv1390

Tuberculist information
Gene namerpoZ
Protein functionProbable DNA-directed RNA polymerase (omega chain) RpoZ (transcriptase omega chain) (RNA polymerase omega subunit)
Functional category(tuberculist)information pathways
Gene location(kb)1565.09
Molecular mass(da)11810.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 110
	  		  	1    VSISQSDASLAAVPAVDQFDPSSGASGGYDTPLGITNPPIDELLDRVSSKYALVIYAAKR   60
			  	61   ARQINDYYNQLGEGILEYVGPLVEPGLQEKPLSIALREIHADLLEHTEGE

Known structures in the PDB
No Known structures
1 12 23 34 45 56 67 78 89 100 111 Range: 41 to 70  |  Coverage: 26% RNA_pol_Rpb6 Range: 35 to 110  |  Coverage: 68% 1 Range: 35 to 110  |  Coverage: 68% 1
Number of amino acids : 110
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
RNA_pol_Rpb6PF0119241-70
Mtb Structural Proteome models
Model Number1
Model nameRv1390
Template1YNJ    KPDBCREDO
Template coverage1_79
Template Identity(%)25.0
Model coverage(%)68.2
Normalized DOPE score0.159

Structure Models from Chopin
Model Number1
Profilea.143.1.1 - 3.90.940.10
Click for model details
zscore4.8
Residue begin35
Residue end110
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1390Gene nameConfidence Score
Rv1389gmk0.973
Rv1391dfp0.915
Rv1391dfp0.915
Rv1699pyrG0.915
Rv1699pyrG0.915
Rv1617pykA0.908
Rv1617pykA0.908
Rv2783cgpsI0.907
Rv2783cgpsI0.907
Rv2783cgpsI0.907
Rv2783cgpsI0.907
Rv2783cgpsI0.907
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
uridine triphosphatePubChem0.9484.141
adenosine triphosphatePubChem0.9507.181
guanosine triphosphatePubChem0.9523.18
cytidine triphosphatePubChem0.9483.156
ara-CTPPubChem0.9483.156