Rv2970c

Tuberculist information
Gene namelipN
Protein functionProbable lipase/esterase LipN
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3324.57
Molecular mass(da)40134.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 376
	  		  	1    MTKSLPGVADLRLGANHPRMWTRRVQGTVVNVGVKVLPWIPTPAKRILSAGRSVIIDGNT   60
			  	61   LDPTLQLMLSTSRIFGVDGLAVDDDIVASRAHMRAICEAMPGPQIHVDVTDLSIPGPAGE  120
			  	121  IPARHYRPSGGGATPLLVFYHGGGWTLGDLDTHDALCRLTCRDADIQVLSIDYRLAPEHP  180
			  	181  APAAVEDAYAAFVWAHEHASDEFGALPGRVAVGGDSAGGNLSAVVCQLARDKARYEGGPT  240
			  	241  PVLQWLLYPRTDFTAQTRSMGLFGNGFLLTKRDIDWFHTQYLRDSDVDPADPRLSPLLAE  300
			  	301  SLSGLAPALIAVAGFDPLRDEGESYAKALRAAGTAVDLRYLGSLTHGFLNLFQLGGGSAA  360
			  	361  GTNELISALRAHLSRV

Known structures in the PDB
No Known structures
1 38 75 112 149 186 223 260 297 334 371 Range: 137 to 350  |  Coverage: 56% Abhydrolase_3 Range: 60 to 369  |  Coverage: 82% 1 Range: 3 to 376  |  Coverage: 99% 1
Number of amino acids : 376
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Abhydrolase_3PF07859137-350
Mtb Structural Proteome models
Model Number1
Model nameRv2970c
Template1JJI    APDBCREDO
Template coverage5_308
Template Identity(%)35.9
Model coverage(%)82.2
Normalized DOPE score-0.864

Structure Models from Chopin
Model Number1
Profilec.69.1.2 - 3.40.50.1820
Click for model details
zscore27.62
Residue begin3
Residue end376
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2970cGene nameConfidence Score
Rv1399cnlhH0.921
Rv1400clipI0.913
Rv0565cRv0565c0.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions