Rv1399c

Tuberculist information
Gene namenlhH
Protein functionProbable non lipolytic carboxylesterase NlhH
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1574.85
Molecular mass(da)33906.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 319
	  		  	1    MTEPTVARPDIDPVLKMLLDTFPVTFTAADGVEVARARLRQLKTPPELLPELRIEERTVG   60
			  	61   YDGLTDIPVRVYWPPVVRDNLPVVVYYHGGGWSLGGLDTHDPVARAHAVGAQAIVVSVDY  120
			  	121  RLAPEHPYPAGIDDSWAALRWVGENAAELGGDPSRIAVAGDSAGGNISAVMAQLARDVGG  180
			  	181  PPLVFQLLWYPTTMADLSLPSFTENADAPILDRDVIDAFLAWYVPGLDISDHTMLPTTLA  240
			  	241  PGNADLSGLPPAFIGTAEHDPLRDDGACYAELLTAAGVSVELSNEPTMVHGYVNFALVVP  300
			  	301  AAAEATGRGLAALKRALHA

Known structures in the PDB
No Known structures
1 32 63 94 125 156 187 218 249 280 311 Range: 84 to 294  |  Coverage: 65% Abhydrolase_3 Range: 11 to 317  |  Coverage: 95% 1 Range: 1 to 319  |  Coverage: 99% 1
Number of amino acids : 319
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Abhydrolase_3PF0785984-294
Mtb Structural Proteome models
Model Number1
Model nameRv1399c
Template1U4N    APDBCREDO
Template coverage3_309
Template Identity(%)44.6
Model coverage(%)95.9
Normalized DOPE score-0.755

Structure Models from Chopin
Model Number1
Profilec.69.1.2 - 3.40.50.1820
Click for model details
zscore31.06
Residue begin1
Residue end319
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1399cGene nameConfidence Score
Rv1400clipI0.976
Rv1397cvapC100.935
Rv2970clipN0.921
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions