Rv1400c

Tuberculist information
Gene namelipI
Protein functionProbable lipase LipH
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1575.83
Molecular mass(da)34052.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 320
	  		  	1    MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDDGIEAVRQRLRDLPRQPVHPELRVVDLA   60
			  	61   IDGPAGPIGTRIYWPPTCPDQAEAPVVLYFHGGGFVMGDLDTHDGTCRQHAVGADAIVVS  120
			  	121  VDYRLAPEHPYPAAIEDAWAATRWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARD  180
			  	181  MGGPPIVFQLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPPAPMA  240
			  	241  PGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQTLVHGYVGYAGVV  300
			  	301  PAATEATNRGLVALRVVLHG

Known structures in the PDB
No Known structures
1 33 65 97 129 161 193 225 257 289 321 Range: 87 to 295  |  Coverage: 65% Abhydrolase_3 Range: 14 to 316  |  Coverage: 94% 1 Range: 1 to 320  |  Coverage: 99% 1
Number of amino acids : 320
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Abhydrolase_3PF0785987-295
Mtb Structural Proteome models
Model Number1
Model nameRv1400c
Template1JJI    APDBCREDO
Template coverage6_309
Template Identity(%)40.9
Model coverage(%)94.4
Normalized DOPE score-0.722

Structure Models from Chopin
Model Number1
Profilec.69.1.2 - 3.40.50.1820
Click for model details
zscore37.68
Residue begin1
Residue end320
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1400cGene nameConfidence Score
Rv1399cnlhH0.976
Rv2970clipN0.913
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions