Rv2856

Tuberculist information
Gene namenicT
Protein functionPossible nickel-transport integral membrane protein NicT
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)3166.68
Molecular mass(da)40534.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 372
	  		  	1    MASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLVEPARLSLGGK   60
			  	61   AFGIGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMSDGHRPLAVGFFFSLGHSTVVFGLA  120
			  	121  VMLVTGLKAIVGPVENDSSTLHHYTGLIGTSISGAFLYLIGILNVIVLVGIVRVFAHLRR  180
			  	181  GDYDEAELEQQLDNRGLLIRFLGRFTKSLTKSWHMYPVGFLFGLGFDTATEIALLVLAGT  240
			  	241  SAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSSPVRKIYYNITVTGLSVA  300
			  	301  VALLIGSVELLGLIANQLGWQGPFWDWLGGLDLNTVGFVVVAMFALTWAIALLVWHYGRV  360
			  	361  EERWTPAPDRTT

Known structures in the PDB
No Known structures
1 38 75 112 149 186 223 260 297 334 371 Range: 63 to 354  |  Coverage: 78% NicO
Number of amino acids : 372
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
NicOPF0382463-354
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2856Gene nameConfidence Score
Rv1852ureG0.952
Rv1848ureA0.942
Rv1850ureC0.939
Rv1850ureC0.939
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
nickelPubChem0.97458.6934