Rv2840c

Tuberculist information
Gene nameRv2840c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3147.96
Molecular mass(da)10601.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 99
	  		  	1    VRTCVGCRKRGLAVELLRVVAVSTGNGNYAVIVDTATSLPGRGAWLHPLRQCAQQAIRRR   60
			  	61   AFARALRIAGSPDTSAVVEYLESLGELEPPGNRTGSNRT

Known structures in the PDB
No Known structures
1 10 19 28 37 46 55 64 73 82 91 Range: 1 to 84  |  Coverage: 83% DUF448 Range: 1 to 84  |  Coverage: 83% 1 Range: 1 to 94  |  Coverage: 93% 1
Number of amino acids : 99
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF448PF042961-84
Mtb Structural Proteome models
Model Number1
Model nameRv2840c
Template1G2R    APDBCREDO
Template coverage8_88
Template Identity(%)22.2
Model coverage(%)83.8
Normalized DOPE score-0.391

Structure Models from Chopin
Model Number1
Profiled.192.1.1 - 3.30.1230.10
Click for model details
zscore18.91
Residue begin1
Residue end94
Binding pockets
STRING
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Protein interacting with Rv2840cGene nameConfidence Score
Rv2839cinfB0.933
Rv2839cinfB0.933
Rv2839cinfB0.933
Rv2839cinfB0.933
Rv2837cRv2837c0.912
Rv2837cRv2837c0.912
Rv2841cnusA0.903
Rv2841cnusA0.903
Rv2838crbfA0.902
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions