Rv2837c

Tuberculist information
Gene nameRv2837c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3143.64
Molecular mass(da)35383.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 336
	  		  	1    VTTIDPRSELVDGRRRAGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLD   60
			  	61   GCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLT  120
			  	121  DSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLAT  180
			  	181  DTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVG  240
			  	241  GRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNL  300
			  	301  AAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALG

Known structures in the PDB
No Known structures
1 34 67 100 133 166 199 232 265 298 331 Range: 29 to 179  |  Coverage: 44% DHH Range: 275 to 333  |  Coverage: 17% DHHA1 Range: 34 to 336  |  Coverage: 89% 1 Range: 31 to 179  |  Coverage: 44% 1 Range: 32 to 336  |  Coverage: 90% 2
Number of amino acids : 336
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DHHPF0136829-179
DHHA1PF02272275-333
Mtb Structural Proteome models
Model Number1
Model nameRv2837c
Template1I74    APDBCREDO
Template coverage1_308
Template Identity(%)16.5
Model coverage(%)89.9
Normalized DOPE score0.06

Structure Models from Chopin
Model Number1
Profilec.107.1.1 - 3.90.1640.10
Click for model details
zscore14.32
Residue begin31
Residue end179
Model Number2
Profilec.107.1.1 - 3.90.1640.10
Click for model details
zscore12.44
Residue begin32
Residue end336
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2837cGene nameConfidence Score
Rv2838crbfA0.971
Rv2839cinfB0.971
Rv2839cinfB0.971
Rv2839cinfB0.971
Rv2839cinfB0.971
Rv2840cRv2840c0.912
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions