SInCRe - Rv2393

Tuberculist information

Gene name	che1
Protein function	Ferrochelatase Che1
Functional category(tuberculist)	intermediary metabolism and respiration
Gene location(kb)	2687.13
Molecular mass(da)	29749.3
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 281

	  		  	1    VTAPATMQSAAMLRSGAIEAPPATMQSAAMRWGHLPLAEESGTIAPQLVLTAHGSKDPRS   60
			  	61   AANARAIAGRLARMRPGLDVRVAFCELNSPNLVDVLNRCRGAAVVTPLLLADAYHARVDI  120
			  	121  PAQIASCRVGHRVRQASVLGEDIRLVSALHERLTELGVSPFDHTLGVVVLAIGSSHPAAN  180
			  	181  ARTSTVASRLAEGTQWAAVTTAFITRPEASLADATDRLRRHGARRMVIAPWLLAPGILSD  240
			  	241  RVRGYAREAGIAMAQPLGAHPMVAATMWDRYRQAVAGRIAA

Known structures in the PDB

No Known structures

Number of amino acids : 281

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
CbiX	PF01903	53-151
CbiX	PF01903	172-269

Mtb Structural Proteome models

Model Number	1
Model name	Rv2393
Template	1QGO APDB CREDO
Template coverage	2_256
Template Identity(%)	19.5
Model coverage(%)	81.9
Normalized DOPE score	-0.151

Model Number	2
Model name	Rv2393.2
Template	1DOZ APDB CREDO
Template coverage	8_308
Template Identity(%)	13.2
Model coverage(%)	94.3
Normalized DOPE score	0.217

Model Number	3
Model name	Rv2393.1
Template	1DOZ APDB CREDO
Template coverage	13_310
Template Identity(%)	11.6
Model coverage(%)	98.2
Normalized DOPE score	0.321

Structure Models from Chopin

Model Number	1
Profile	c.92.1.3 - 3.40.50.1400 Click for model details
zscore	13.63
Residue begin	43
Residue end	157

Model Number	2
Profile	c.92.1.2 Click for model details
zscore	10.91
Residue begin	7
Residue end	277

Binding pockets

STRING

Cytoscape Web will replace the contents of this div with protein-protein interaction network.

Protein interacting with Rv2393	Gene name	Confidence Score
Rv2392	cysH	0.952
Rv2847c	cysG	0.946
Rv2847c	cysG	0.946
Rv2065	cobH	0.93

Potential ligand/drug binding sites

Protein Model	Pocket Number	Drug Binding Site	PMIN Score	Pvalue PMIN	PMAX Score	Pvalue PMAX
Rv2393.2	1	3bbt_FMM_D_91 PDB CREDO	0.737	0.055	0.712	0.000
Rv2393.1	2	3sm2_478_A_126 PDB CREDO	0.730	0.060	0.694	0.000
Rv2393.2	4	3h52_486_A_3 PDB CREDO	0.682	0.095	0.682	0.000
Rv2393.2	4	3e22_LOC_B_700 PDB CREDO	0.725	0.063	0.681	0.000
Rv2393.2	4	3e22_LOC_D_700 PDB CREDO	0.721	0.066	0.677	0.000
Rv2393.2	4	3h52_486_D_2 PDB CREDO	0.666	0.110	0.666	0.001
Rv2393.2	4	3h52_486_B_1 PDB CREDO	0.685	0.093	0.664	0.001
Rv2393.2	4	1sa1_POD_D_701 PDB CREDO	0.678	0.099	0.658	0.001
Rv2393.1	2	2q64_1UN_B_1001 PDB CREDO	0.674	0.102	0.657	0.001
Rv2393.1	2	2qak_1UN_A_1001 PDB CREDO	0.672	0.104	0.655	0.001
Rv2393.1	2	2pyn_1UN_A_1001 PDB CREDO	0.671	0.104	0.655	0.001
Rv2393.2	1	1jg2_ADN_A_500 PDB CREDO	0.655	0.120	0.655	0.001
Rv2393.2	4	1sa1_POD_B_700 PDB CREDO	0.693	0.086	0.653	0.001
Rv2393.1	2	2pym_1UN_A_1001 PDB CREDO	0.669	0.107	0.652	0.001
Rv2393.1	2	2q63_1UN_A_1001 PDB CREDO	0.666	0.109	0.650	0.001
Rv2393.1	2	1ya4_CTX_A_1 PDB CREDO	0.665	0.110	0.649	0.001
Rv2393.2	1	3bbt_FMM_B_91 PDB CREDO	0.776	0.034	0.647	0.001
Rv2393.1	2	1xkk_FMM_A_91 PDB CREDO	0.715	0.070	0.646	0.001
Rv2393.2	1	1s9p_DES_A_459 PDB CREDO	0.665	0.110	0.642	0.001
Rv2393.2	1	3oht_1N1_B_1000 PDB CREDO	0.662	0.113	0.639	0.001
Rv2393.2	1	1mx1_THA_C_3 PDB CREDO	0.661	0.114	0.638	0.001
Rv2393.1	2	3ufn_ROC_A_401 PDB CREDO	0.716	0.069	0.631	0.001
Rv2393.2	1	3h0a_9RA_A_500 PDB CREDO	0.647	0.127	0.625	0.001
Rv2393.2	4	2oax_SNL_E_5001 PDB CREDO	0.641	0.133	0.622	0.001
Rv2393.2	4	2oax_SNL_F_6001 PDB CREDO	0.640	0.135	0.621	0.001
Rv2393.2	1	1ya3_STR_A_1001 PDB CREDO	0.619	0.156	0.619	0.001
Rv2393.2	4	2oax_SNL_D_4001 PDB CREDO	0.638	0.137	0.619	0.001
Rv2393.1	2	2qxs_RAL_A_600 PDB CREDO	0.760	0.042	0.618	0.001
Rv2393.1	2	2qxs_RAL_B_600 PDB CREDO	0.760	0.042	0.618	0.001
Rv2393.2	1	1ya3_STR_B_2001 PDB CREDO	0.616	0.160	0.616	0.002
Rv2393.2	5	1uay_ADN_A_1001 PDB CREDO	0.645	0.130	0.615	0.002
Rv2393.2	1	3spk_TPV_A_100 PDB CREDO	0.658	0.117	0.615	0.002
Rv2393.2	4	2oax_SNL_A_1001 PDB CREDO	0.632	0.143	0.613	0.002
Rv2393.2	1	1jg3_ADN_A_500 PDB CREDO	0.681	0.096	0.612	0.002
Rv2393.2	1	1s9p_DES_D_600 PDB CREDO	0.633	0.141	0.612	0.002
Rv2393.2	1	2h77_T3_A_1 PDB CREDO	0.649	0.125	0.606	0.002
Rv2393.1	2	2f80_017_B_301 PDB CREDO	0.621	0.155	0.606	0.002
Rv2393.2	1	2q1v_PDN_A_248 PDB CREDO	0.605	0.173	0.605	0.002
Rv2393.2	1	2h42_VIA_A_901 PDB CREDO	0.625	0.150	0.604	0.002
Rv2393.2	1	1nhz_486_A_800 PDB CREDO	0.646	0.128	0.603	0.002
Rv2393.2	1	3erd_DES_A_600 PDB CREDO	0.647	0.128	0.603	0.002
Rv2393.2	1	3erd_DES_B_800 PDB CREDO	0.647	0.128	0.603	0.002
Rv2393.2	1	3oct_1N1_A_663 PDB CREDO	0.603	0.176	0.603	0.002
Rv2393.2	4	1y0x_T44_X_500 PDB CREDO	0.602	0.177	0.602	0.002
Rv2393.2	1	2xkw_P1B_B_1475 PDB CREDO	0.645	0.129	0.601	0.002
Rv2393.2	1	3rif_IVM_A_403 PDB CREDO	0.645	0.129	0.601	0.002
Rv2393.2	1	3rif_IVM_D_402 PDB CREDO	0.645	0.129	0.601	0.002
Rv2393.2	4	3spk_TPV_B_100 PDB CREDO	0.657	0.117	0.601	0.002
Rv2393.2	1	3rif_IVM_A_402 PDB CREDO	0.644	0.130	0.600	0.002
Rv2393.2	1	3rif_IVM_B_403 PDB CREDO	0.642	0.132	0.598	0.002
Rv2393.2	1	1zgy_BRL_A_503 PDB CREDO	0.641	0.134	0.598	0.002
Rv2393.2	4	3uvv_T3_A_501 PDB CREDO	0.657	0.118	0.598	0.002
Rv2393.2	4	1xzx_T3_X_500 PDB CREDO	0.655	0.119	0.597	0.002
Rv2393.2	1	2h79_T3_A_1 PDB CREDO	0.661	0.114	0.597	0.002
Rv2393.2	1	3ri5_IVM_C_350 PDB CREDO	0.640	0.134	0.596	0.002
Rv2393.2	1	1fm6_BRL_D_503 PDB CREDO	0.617	0.159	0.596	0.002
Rv2393.2	1	3ria_IVM_C_349 PDB CREDO	0.640	0.135	0.596	0.002
Rv2393.1	2	3ogq_AB1_A_200 PDB CREDO	0.641	0.133	0.595	0.002
Rv2393.2	4	1a28_STR_B_2 PDB CREDO	0.653	0.122	0.594	0.002
Rv2393.2	1	3jwq_VIA_D_901 PDB CREDO	0.615	0.161	0.594	0.002
Rv2393.1	2	3el4_ROC_A_100 PDB CREDO	0.638	0.137	0.593	0.002
Rv2393.1	2	3gp0_NIL_A_1 PDB CREDO	0.673	0.103	0.593	0.002
Rv2393.2	4	1err_RAL_A_600 PDB CREDO	0.611	0.166	0.593	0.002
Rv2393.2	4	1err_RAL_B_600 PDB CREDO	0.610	0.168	0.591	0.002
Rv2393.2	4	2jfa_RAL_B_600 PDB CREDO	0.609	0.168	0.591	0.002
Rv2393.2	1	3gws_T3_X_500 PDB CREDO	0.675	0.102	0.590	0.003
Rv2393.2	1	2prg_BRL_A_1 PDB CREDO	0.610	0.168	0.589	0.003
Rv2393.2	4	3bbt_FMM_D_91 PDB CREDO	0.738	0.055	0.588	0.003
Rv2393.2	1	1bsx_T3_A_1 PDB CREDO	0.673	0.103	0.588	0.003
Rv2393.2	1	1bsx_T3_B_2 PDB CREDO	0.673	0.103	0.588	0.003
Rv2393.2	1	1mx1_THA_E_5 PDB CREDO	0.653	0.121	0.587	0.003
Rv2393.2	1	3uvv_T3_A_501 PDB CREDO	0.692	0.087	0.586	0.003
Rv2393.1	2	2aof_FRD_C_305 PDB CREDO	0.644	0.130	0.585	0.003
Rv2393.2	1	1xzx_T3_X_500 PDB CREDO	0.690	0.088	0.584	0.003
Rv2393.2	4	2oax_SNL_B_2001 PDB CREDO	0.621	0.155	0.583	0.003
Rv2393.2	4	3gws_T3_X_500 PDB CREDO	0.662	0.113	0.583	0.003
Rv2393.2	4	3mnp_DEX_A_784 PDB CREDO	0.601	0.178	0.583	0.003
Rv2393.2	4	1bsx_T3_A_1 PDB CREDO	0.660	0.114	0.582	0.003
Rv2393.2	4	1bsx_T3_B_2 PDB CREDO	0.660	0.114	0.582	0.003
Rv2393.2	1	3h52_486_C_4 PDB CREDO	0.625	0.151	0.582	0.003
Rv2393.2	1	3oht_1N1_A_1000 PDB CREDO	0.672	0.104	0.582	0.003
Rv2393.2	1	3adx_IMN_B_3 PDB CREDO	0.784	0.031	0.581	0.003
Rv2393.2	4	3mno_DEX_A_784 PDB CREDO	0.600	0.180	0.581	0.003
Rv2393.2	1	3ln1_CEL_D_682 PDB CREDO	0.600	0.179	0.580	0.003
Rv2393.2	4	3ut5_LOC_B_502 PDB CREDO	0.579	0.204	0.579	0.003
Rv2393.2	4	2oax_SNL_C_3001 PDB CREDO	0.616	0.160	0.579	0.003
Rv2393.1	2	2aoi_FRD_C_305 PDB CREDO	0.593	0.188	0.578	0.003
Rv2393.2	4	3vhu_SNL_A_1001 PDB CREDO	0.615	0.161	0.578	0.003
Rv2393.1	2	1rl8_RIT_A_9001 PDB CREDO	0.577	0.208	0.577	0.003
Rv2393.2	4	1n49_RIT_D_401 PDB CREDO	0.648	0.126	0.576	0.003
Rv2393.1	2	1t7i_017_A_200 PDB CREDO	0.618	0.158	0.575	0.003
Rv2393.2	1	1sqn_NDR_A_1001 PDB CREDO	0.595	0.185	0.575	0.003
Rv2393.2	1	1p93_DEX_B_2999 PDB CREDO	0.595	0.185	0.575	0.003
Rv2393.2	1	1p93_DEX_A_1999 PDB CREDO	0.594	0.186	0.574	0.003
Rv2393.2	4	2ab2_SNL_A_502 PDB CREDO	0.610	0.167	0.573	0.003
Rv2393.2	4	2ab2_SNL_B_503 PDB CREDO	0.610	0.167	0.573	0.003
Rv2393.2	1	3e22_LOC_D_700 PDB CREDO	0.699	0.081	0.573	0.003
Rv2393.2	1	3e22_LOC_B_700 PDB CREDO	0.699	0.082	0.573	0.003
Rv2393.1	2	3bvb_017_B_401 PDB CREDO	0.587	0.195	0.572	0.003
Rv2393.2	4	2aoh_FRD_C_305 PDB CREDO	0.590	0.191	0.572	0.003
Rv2393.1	2	1sa1_POD_B_700 PDB CREDO	0.834	0.014	0.572	0.003
Rv2393.1	2	1t46_STI_A_3 PDB CREDO	0.666	0.109	0.572	0.003
Rv2393.2	4	2h42_VIA_A_901 PDB CREDO	0.716	0.069	0.571	0.004
Rv2393.2	4	2qxs_RAL_B_600 PDB CREDO	0.718	0.067	0.571	0.004
Rv2393.2	1	1sqn_NDR_B_2001 PDB CREDO	0.590	0.191	0.570	0.004
Rv2393.2	1	2fum_MIX_D_3539 PDB CREDO	0.590	0.191	0.570	0.004
Rv2393.2	1	2aa6_STR_B_402 PDB CREDO	0.630	0.145	0.569	0.004
Rv2393.2	4	2w8y_486_A_1000 PDB CREDO	0.604	0.174	0.569	0.004
Rv2393.2	1	2aa6_STR_A_401 PDB CREDO	0.630	0.145	0.569	0.004
Rv2393.1	2	3ucb_017_A_201 PDB CREDO	0.597	0.182	0.569	0.004
Rv2393.1	2	1c6z_ROC_B_505 PDB CREDO	0.583	0.200	0.569	0.004
Rv2393.2	5	2uxp_CLM_B_1211 PDB CREDO	0.596	0.184	0.569	0.004
Rv2393.2	5	4dta_ADN_A_401 PDB CREDO	0.623	0.152	0.569	0.004
Rv2393.2	1	1gs4_ZK5_A_1918 PDB CREDO	0.610	0.167	0.569	0.004
Rv2393.2	1	3k54_1N1_A_1 PDB CREDO	0.633	0.142	0.569	0.004
Rv2393.2	1	2aax_PDN_A_502 PDB CREDO	0.629	0.146	0.568	0.004
Rv2393.2	1	2aax_PDN_B_503 PDB CREDO	0.629	0.146	0.568	0.004
Rv2393.2	1	3qt0_486_A_4 PDB CREDO	0.587	0.194	0.568	0.004
Rv2393.1	2	2nnk_ROC_A_401 PDB CREDO	0.595	0.185	0.567	0.004
Rv2393.2	4	2qxs_RAL_A_600 PDB CREDO	0.714	0.071	0.567	0.004
Rv2393.2	1	2y6o_1N1_A_1892 PDB CREDO	0.670	0.106	0.567	0.004
Rv2393.2	4	3ut5_LOC_D_502 PDB CREDO	0.603	0.176	0.566	0.004
Rv2393.1	2	3ndt_ROC_D_100 PDB CREDO	0.593	0.188	0.565	0.004
Rv2393.2	5	2uxp_CLM_A_1211 PDB CREDO	0.590	0.191	0.563	0.004
Rv2393.2	1	2h42_VIA_C_903 PDB CREDO	0.605	0.174	0.563	0.004
Rv2393.2	1	2ito_IRE_A_2020 PDB CREDO	0.676	0.101	0.563	0.004
Rv2393.2	4	2h79_T3_A_1 PDB CREDO	0.660	0.115	0.563	0.004
Rv2393.2	4	3frq_ERY_B_195 PDB CREDO	0.599	0.181	0.563	0.004
Rv2393.1	2	1n49_RIT_B_301 PDB CREDO	0.710	0.074	0.562	0.004
Rv2393.2	4	2hw2_RFP_A_1200 PDB CREDO	0.597	0.182	0.561	0.004
Rv2393.1	2	1sa1_POD_D_701 PDB CREDO	0.842	0.012	0.561	0.004
Rv2393.2	4	3jwq_VIA_D_901 PDB CREDO	0.703	0.079	0.560	0.004
Rv2393.2	5	3r9c_ECL_A_452 PDB CREDO	0.700	0.081	0.560	0.004
Rv2393.2	1	3ri5_IVM_A_349 PDB CREDO	0.672	0.104	0.560	0.004
Rv2393.2	4	1nhz_486_A_800 PDB CREDO	0.679	0.098	0.560	0.004
Rv2393.2	4	2jfa_RAL_A_600 PDB CREDO	0.596	0.184	0.560	0.004
Rv2393.2	1	3mne_DEX_A_784 PDB CREDO	0.640	0.134	0.559	0.004
Rv2393.2	1	1sa1_POD_D_701 PDB CREDO	0.748	0.049	0.559	0.004
Rv2393.2	4	1p93_DEX_D_4999 PDB CREDO	0.634	0.141	0.559	0.004
Rv2393.2	4	3spk_TPV_A_100 PDB CREDO	0.677	0.099	0.559	0.004
Rv2393.2	1	1a28_STR_A_1 PDB CREDO	0.578	0.206	0.558	0.004
Rv2393.2	1	1ya3_STR_C_3001 PDB CREDO	0.622	0.154	0.558	0.004
Rv2393.2	1	3ria_IVM_E_349 PDB CREDO	0.670	0.106	0.558	0.004
Rv2393.2	1	2xpv_MIY_A_1209 PDB CREDO	0.578	0.207	0.558	0.004
Rv2393.2	1	3rhw_IVM_A_348 PDB CREDO	0.669	0.106	0.558	0.004
Rv2393.2	1	1a28_STR_B_2 PDB CREDO	0.659	0.116	0.558	0.004
Rv2393.2	1	3ut5_LOC_D_502 PDB CREDO	0.680	0.097	0.558	0.004
Rv2393.2	1	1qkn_RAL_A_600 PDB CREDO	0.638	0.137	0.557	0.004
Rv2393.1	2	1hxb_ROC_A_100 PDB CREDO	0.571	0.215	0.557	0.004
Rv2393.2	1	2prg_BRL_B_2 PDB CREDO	0.577	0.208	0.557	0.004
Rv2393.2	1	3sxr_1N1_A_1 PDB CREDO	0.722	0.065	0.557	0.004
Rv2393.2	4	3erd_DES_B_800 PDB CREDO	0.776	0.035	0.557	0.004
Rv2393.2	4	3mne_DEX_A_784 PDB CREDO	0.632	0.143	0.557	0.004
Rv2393.1	2	1n49_RIT_D_401 PDB CREDO	0.765	0.040	0.556	0.005
Rv2393.2	1	3jwq_VIA_B_901 PDB CREDO	0.597	0.183	0.556	0.005
Rv2393.2	4	3heg_BAX_A_1 PDB CREDO	0.572	0.213	0.555	0.005
Rv2393.2	4	1m2z_DEX_D_401 PDB CREDO	0.630	0.145	0.555	0.005
Rv2393.2	4	1p93_DEX_C_3999 PDB CREDO	0.630	0.145	0.555	0.005
Rv2393.2	4	3so9_017_A_100 PDB CREDO	0.555	0.237	0.555	0.005
Rv2393.2	1	3rif_IVM_E_402 PDB CREDO	0.665	0.110	0.555	0.005
Rv2393.2	4	1m2z_DEX_A_301 PDB CREDO	0.629	0.146	0.554	0.005
Rv2393.2	1	1p93_DEX_D_4999 PDB CREDO	0.634	0.141	0.554	0.005
Rv2393.2	1	3ri5_IVM_B_349 PDB CREDO	0.665	0.110	0.554	0.005
Rv2393.2	4	3gn8_DEX_B_247 PDB CREDO	0.628	0.147	0.554	0.005
Rv2393.1	2	1k6c_MK1_B_902 PDB CREDO	0.595	0.185	0.554	0.005
Rv2393.2	1	3ri5_IVM_D_349 PDB CREDO	0.664	0.111	0.554	0.005
Rv2393.1	2	3k4v_ROC_D_201 PDB CREDO	0.609	0.169	0.553	0.005
Rv2393.2	4	2h77_T3_A_1 PDB CREDO	0.670	0.106	0.553	0.005
Rv2393.2	4	3b0w_DGX_A_1 PDB CREDO	0.587	0.195	0.553	0.005
Rv2393.2	1	3ria_IVM_E_348 PDB CREDO	0.663	0.112	0.552	0.005
Rv2393.2	1	1p93_DEX_C_3999 PDB CREDO	0.632	0.143	0.552	0.005
Rv2393.2	4	1s9p_DES_A_459 PDB CREDO	0.742	0.052	0.552	0.005
Rv2393.2	4	1s9p_DES_D_600 PDB CREDO	0.742	0.052	0.552	0.005
Rv2393.2	1	1fm6_BRL_X_504 PDB CREDO	0.652	0.122	0.552	0.005
Rv2393.2	5	3hm1_J3Z_A_2 PDB CREDO	0.578	0.206	0.552	0.005
Rv2393.2	1	3rhw_IVM_B_348 PDB CREDO	0.662	0.113	0.552	0.005
Rv2393.2	1	3ria_IVM_A_348 PDB CREDO	0.662	0.113	0.552	0.005
Rv2393.2	5	2x7h_PFN_A_1372 PDB CREDO	0.551	0.242	0.551	0.005
Rv2393.2	1	3ria_IVM_C_350 PDB CREDO	0.661	0.114	0.551	0.005
Rv2393.2	1	1m2z_DEX_D_401 PDB CREDO	0.630	0.145	0.551	0.005
Rv2393.2	1	1sa1_POD_B_700 PDB CREDO	0.759	0.043	0.551	0.005
Rv2393.2	4	1mx1_THA_C_3 PDB CREDO	0.740	0.053	0.551	0.005
Rv2393.2	4	3gn8_DEX_A_247 PDB CREDO	0.625	0.151	0.551	0.005
Rv2393.2	1	1jg3_ADN_B_550 PDB CREDO	0.686	0.092	0.551	0.005
Rv2393.2	1	3rhw_IVM_D_348 PDB CREDO	0.660	0.114	0.551	0.005
Rv2393.2	1	3rhw_IVM_D_349 PDB CREDO	0.660	0.114	0.551	0.005
Rv2393.2	1	3h52_486_D_2 PDB CREDO	0.714	0.071	0.550	0.005
Rv2393.2	1	3gn8_DEX_B_247 PDB CREDO	0.629	0.147	0.549	0.005
Rv2393.2	1	3rhw_IVM_B_349 PDB CREDO	0.659	0.116	0.549	0.005
Rv2393.1	2	2nnp_ROC_A_401 PDB CREDO	0.590	0.192	0.548	0.005
Rv2393.2	1	1m2z_DEX_A_301 PDB CREDO	0.627	0.148	0.548	0.005
Rv2393.2	1	3gn8_DEX_A_247 PDB CREDO	0.627	0.148	0.548	0.005
Rv2393.1	2	3pwr_ROC_A_401 PDB CREDO	0.562	0.228	0.548	0.005
Rv2393.2	4	1fm6_BRL_X_504 PDB CREDO	0.602	0.177	0.548	0.005
Rv2393.2	1	1mx1_THA_F_6 PDB CREDO	0.709	0.074	0.547	0.005
Rv2393.2	1	1ya4_CTX_B_2 PDB CREDO	0.709	0.074	0.547	0.005
Rv2393.2	1	1g50_EST_A_600 PDB CREDO	0.736	0.056	0.546	0.005
Rv2393.2	1	2gqg_1N1_A_501 PDB CREDO	0.586	0.197	0.546	0.005
Rv2393.2	1	1lhu_EST_A_301 PDB CREDO	0.565	0.224	0.545	0.005
Rv2393.2	4	2aa6_STR_A_401 PDB CREDO	0.639	0.136	0.545	0.005
Rv2393.2	4	2aax_PDN_B_503 PDB CREDO	0.639	0.136	0.545	0.005
Rv2393.2	1	1ya4_CTX_C_3 PDB CREDO	0.706	0.076	0.544	0.005
Rv2393.2	4	2aax_PDN_A_502 PDB CREDO	0.638	0.137	0.544	0.006
Rv2393.2	5	3ug2_IRE_A_1 PDB CREDO	0.599	0.180	0.544	0.006
Rv2393.2	1	3uud_EST_A_600 PDB CREDO	0.733	0.058	0.543	0.006
Rv2393.2	4	2aa6_STR_B_402 PDB CREDO	0.636	0.139	0.543	0.006
Rv2393.2	4	3b0w_DGX_B_1 PDB CREDO	0.646	0.128	0.542	0.006
Rv2393.2	4	1ya3_STR_A_1001 PDB CREDO	0.703	0.079	0.542	0.006
Rv2393.2	5	3rem_SAL_A_301 PDB CREDO	0.627	0.148	0.542	0.006
Rv2393.2	1	1mx1_THA_D_4 PDB CREDO	0.702	0.079	0.541	0.006
Rv2393.2	4	2aoj_FRD_C_305 PDB CREDO	0.592	0.189	0.541	0.006
Rv2393.2	4	3frq_ERY_A_195 PDB CREDO	0.592	0.189	0.541	0.006
Rv2393.2	1	2aa5_STR_A_301 PDB CREDO	0.599	0.180	0.541	0.006
Rv2393.2	1	3ads_IMN_B_3 PDB CREDO	0.827	0.016	0.541	0.006
Rv2393.2	4	1zgy_BRL_A_503 PDB CREDO	0.655	0.119	0.541	0.006
Rv2393.2	1	2aa5_STR_B_302 PDB CREDO	0.598	0.181	0.540	0.006
Rv2393.2	1	3h52_486_A_3 PDB CREDO	0.701	0.080	0.540	0.006
Rv2393.2	4	3h0a_9RA_A_500 PDB CREDO	0.677	0.100	0.540	0.006
Rv2393.2	1	3uud_EST_B_600 PDB CREDO	0.728	0.061	0.540	0.006
Rv2393.2	1	3ols_EST_A_600 PDB CREDO	0.727	0.061	0.539	0.006
Rv2393.2	4	3gcs_BAX_A_401 PDB CREDO	0.572	0.214	0.539	0.006
Rv2393.2	1	3ols_EST_B_600 PDB CREDO	0.726	0.062	0.538	0.006
Rv2393.2	4	1xkk_FMM_A_91 PDB CREDO	0.753	0.046	0.538	0.006
Rv2393.1	2	3d1y_ROC_A_201 PDB CREDO	0.537	0.262	0.537	0.006
Rv2393.2	1	1s9p_DES_B_459 PDB CREDO	0.696	0.084	0.537	0.006
Rv2393.2	1	3sxr_1N1_B_2 PDB CREDO	0.724	0.064	0.537	0.006
Rv2393.2	1	2fum_MIX_A_539 PDB CREDO	0.575	0.210	0.536	0.006
Rv2393.1	2	3el5_1UN_B_201 PDB CREDO	0.563	0.226	0.536	0.006
Rv2393.2	1	2ab2_SNL_A_502 PDB CREDO	0.653	0.121	0.536	0.006
Rv2393.2	1	3d90_NOG_A_1001 PDB CREDO	0.574	0.212	0.536	0.006
Rv2393.2	1	1s9p_DES_C_500 PDB CREDO	0.693	0.086	0.535	0.006
Rv2393.2	1	2yja_EST_B_1550 PDB CREDO	0.722	0.065	0.535	0.006
Rv2393.2	1	2oax_SNL_C_3001 PDB CREDO	0.652	0.122	0.535	0.006
Rv2393.1	2	3ndu_ROC_D_100 PDB CREDO	0.616	0.161	0.534	0.006
Rv2393.2	1	3g5d_1N1_B_1 PDB CREDO	0.666	0.109	0.534	0.006
Rv2393.2	1	3d90_NOG_B_2001 PDB CREDO	0.572	0.215	0.534	0.006
Rv2393.1	2	3spk_TPV_B_100 PDB CREDO	0.756	0.045	0.534	0.006
Rv2393.2	1	2ab2_SNL_B_503 PDB CREDO	0.651	0.124	0.534	0.006
Rv2393.2	1	2jfa_RAL_A_600 PDB CREDO	0.651	0.124	0.534	0.006
Rv2393.2	5	1sn0_T44_C_601 PDB CREDO	0.585	0.198	0.533	0.007
Rv2393.2	5	1r9o_FLP_A_501 PDB CREDO	0.558	0.233	0.533	0.007
Rv2393.2	4	3ufn_ROC_A_401 PDB CREDO	0.726	0.062	0.532	0.007
Rv2393.2	1	2cbr_A80_A_201 PDB CREDO	0.615	0.162	0.532	0.007
Rv2393.2	1	1y0x_T44_X_500 PDB CREDO	0.690	0.088	0.532	0.007
Rv2393.2	1	3h52_486_B_1 PDB CREDO	0.711	0.072	0.532	0.007
Rv2393.1	2	3el0_1UN_A_201 PDB CREDO	0.691	0.088	0.531	0.007
Rv2393.2	4	1uwh_BAX_B_1723 PDB CREDO	0.531	0.271	0.531	0.007
Rv2393.2	4	1n49_RIT_B_301 PDB CREDO	0.650	0.124	0.531	0.007
Rv2393.2	1	3frq_ERY_B_195 PDB CREDO	0.647	0.127	0.531	0.007
Rv2393.2	4	1uwh_BAX_A_1723 PDB CREDO	0.531	0.272	0.531	0.007
Rv2393.2	4	1ya4_CTX_B_2 PDB CREDO	0.893	0.004	0.531	0.007
Rv2393.2	1	3ut5_LOC_B_502 PDB CREDO	0.688	0.090	0.530	0.007
Rv2393.1	2	3h52_486_B_1 PDB CREDO	0.795	0.027	0.529	0.007
Rv2393.2	1	3qlg_1N1_A_601 PDB CREDO	0.660	0.115	0.529	0.007
Rv2393.2	1	1err_RAL_A_600 PDB CREDO	0.666	0.109	0.529	0.007
Rv2393.2	1	1lhv_NOG_A_301 PDB CREDO	0.625	0.150	0.529	0.007
Rv2393.2	1	3vhu_SNL_A_1001 PDB CREDO	0.645	0.130	0.529	0.007
Rv2393.1	2	3lzv_017_A_200 PDB CREDO	0.687	0.091	0.529	0.007
Rv2393.1	2	3e22_LOC_B_700 PDB CREDO	0.870	0.007	0.528	0.007
Rv2393.2	1	2uxo_TAC_B_1211 PDB CREDO	0.713	0.071	0.528	0.007
Rv2393.2	1	3g5d_1N1_A_1 PDB CREDO	0.658	0.116	0.528	0.007
Rv2393.2	1	2oax_SNL_B_2001 PDB CREDO	0.644	0.131	0.528	0.007
Rv2393.2	4	1jg2_ADN_A_500 PDB CREDO	0.685	0.093	0.528	0.007
Rv2393.2	1	1err_RAL_B_600 PDB CREDO	0.664	0.111	0.527	0.007
Rv2393.2	1	3ln1_CEL_A_682 PDB CREDO	0.603	0.175	0.527	0.007
Rv2393.1	2	2xkw_P1B_A_1478 PDB CREDO	0.568	0.219	0.527	0.007
Rv2393.2	4	1z2b_VLB_C_800 PDB CREDO	0.543	0.254	0.527	0.007
Rv2393.2	1	3ln1_CEL_C_682 PDB CREDO	0.603	0.176	0.527	0.007
Rv2393.1	2	3e22_LOC_D_700 PDB CREDO	0.867	0.007	0.526	0.007
Rv2393.2	1	2hw2_RFP_A_1200 PDB CREDO	0.642	0.133	0.526	0.007
Rv2393.2	5	3rem_SAL_B_301 PDB CREDO	0.609	0.168	0.526	0.007
Rv2393.2	1	3ln1_CEL_B_682 PDB CREDO	0.601	0.177	0.526	0.007
Rv2393.2	1	3mnp_DEX_A_784 PDB CREDO	0.660	0.115	0.525	0.008
Rv2393.2	4	1qkn_RAL_A_600 PDB CREDO	0.595	0.185	0.524	0.008
Rv2393.2	1	3qlg_1N1_B_601 PDB CREDO	0.653	0.121	0.524	0.008
Rv2393.1	2	2v0z_C41_O_1327 PDB CREDO	0.594	0.186	0.524	0.008
Rv2393.1	2	3kk6_CEL_A_701 PDB CREDO	0.579	0.205	0.524	0.008
Rv2393.2	5	3ads_IMN_B_3 PDB CREDO	0.627	0.148	0.524	0.008
Rv2393.2	4	1ya3_STR_B_2001 PDB CREDO	0.679	0.098	0.523	0.008
Rv2393.2	1	2ity_IRE_A_2020 PDB CREDO	0.678	0.099	0.523	0.008
Rv2393.2	4	3sm2_478_A_126 PDB CREDO	0.770	0.038	0.522	0.008
Rv2393.2	4	1ya4_CTX_C_3 PDB CREDO	0.878	0.005	0.522	0.008
Rv2393.2	4	3qt0_486_A_4 PDB CREDO	0.655	0.120	0.522	0.008
Rv2393.2	1	2jfa_RAL_B_600 PDB CREDO	0.656	0.118	0.522	0.008
Rv2393.2	5	3ads_IMN_A_1 PDB CREDO	0.636	0.139	0.522	0.008
Rv2393.2	1	3kw2_ADN_B_300 PDB CREDO	0.676	0.100	0.521	0.008
Rv2393.2	4	3vn2_TLS_A_501 PDB CREDO	0.537	0.262	0.521	0.008
Rv2393.2	1	3mno_DEX_A_784 PDB CREDO	0.656	0.119	0.521	0.008
Rv2393.1	2	2v0z_C41_C_1328 PDB CREDO	0.547	0.248	0.520	0.008
Rv2393.2	1	1uwh_BAX_A_1723 PDB CREDO	0.675	0.102	0.520	0.008
Rv2393.2	1	2h42_VIA_B_902 PDB CREDO	0.558	0.233	0.520	0.008
Rv2393.2	1	2zva_1N1_A_513 PDB CREDO	0.674	0.102	0.520	0.008
Rv2393.2	4	3el0_1UN_A_201 PDB CREDO	0.619	0.157	0.520	0.008
Rv2393.2	5	3rf4_FUN_A_201 PDB CREDO	0.601	0.177	0.519	0.008
Rv2393.2	1	1uwh_BAX_B_1723 PDB CREDO	0.674	0.102	0.519	0.008
Rv2393.2	1	3ri5_IVM_E_349 PDB CREDO	0.672	0.104	0.518	0.008
Rv2393.1	2	3frq_ERY_A_195 PDB CREDO	0.733	0.058	0.518	0.008
Rv2393.2	1	3oez_STI_B_601 PDB CREDO	0.632	0.143	0.518	0.008
Rv2393.1	2	3oxc_ROC_A_401 PDB CREDO	0.667	0.109	0.518	0.008
Rv2393.2	1	3tkd_CYZ_B_267 PDB CREDO	0.672	0.104	0.517	0.008
Rv2393.2	4	3erd_DES_A_600 PDB CREDO	0.721	0.066	0.517	0.008
Rv2393.1	2	3s56_ROC_A_201 PDB CREDO	0.618	0.158	0.517	0.008
Rv2393.2	4	4asd_BAX_A_1500 PDB CREDO	0.549	0.246	0.517	0.008
Rv2393.2	4	2aa5_STR_A_301 PDB CREDO	0.605	0.172	0.517	0.008
Rv2393.2	1	2oax_SNL_D_4001 PDB CREDO	0.691	0.088	0.517	0.008
Rv2393.2	4	3ogp_017_A_200 PDB CREDO	0.532	0.269	0.517	0.008
Rv2393.1	2	3tkg_ROC_C_901 PDB CREDO	0.581	0.202	0.516	0.009
Rv2393.2	5	3rf4_FUN_C_203 PDB CREDO	0.597	0.182	0.516	0.009
Rv2393.2	5	3s20_CER_B_1 PDB CREDO	0.541	0.256	0.516	0.009
Rv2393.2	4	1p93_DEX_A_1999 PDB CREDO	0.646	0.128	0.516	0.009
Rv2393.2	1	2oax_SNL_E_5001 PDB CREDO	0.690	0.089	0.516	0.009
Rv2393.1	2	3ggu_017_B_201 PDB CREDO	0.570	0.217	0.516	0.009
Rv2393.2	1	3kw2_ADN_A_300 PDB CREDO	0.595	0.185	0.515	0.009
Rv2393.2	4	2q1v_PDN_A_248 PDB CREDO	0.668	0.107	0.515	0.009
Rv2393.2	4	3gp0_NIL_A_1 PDB CREDO	0.703	0.079	0.515	0.009
Rv2393.2	1	1cil_ETS_A_263 PDB CREDO	0.532	0.269	0.514	0.009
Rv2393.2	1	4eyb_0WO_A_303 PDB CREDO	0.533	0.269	0.514	0.009
Rv2393.2	5	3rf4_FUN_B_202 PDB CREDO	0.595	0.185	0.514	0.009
Rv2393.2	4	2aa5_STR_B_302 PDB CREDO	0.602	0.176	0.514	0.009
Rv2393.1	2	1hsh_MK1_A_401 PDB CREDO	0.614	0.162	0.513	0.009
Rv2393.2	1	2oax_SNL_A_1001 PDB CREDO	0.687	0.091	0.513	0.009
Rv2393.2	1	2oax_SNL_F_6001 PDB CREDO	0.687	0.091	0.513	0.009
Rv2393.1	2	3h52_486_A_3 PDB CREDO	0.794	0.027	0.513	0.009
Rv2393.2	1	3cs8_BRL_A_503 PDB CREDO	0.665	0.110	0.513	0.009
Rv2393.1	2	2nmy_ROC_A_401 PDB CREDO	0.605	0.173	0.513	0.009
Rv2393.2	4	1uwj_BAX_A_1723 PDB CREDO	0.593	0.187	0.512	0.009
Rv2393.1	2	3bjw_SVR_B_501 PDB CREDO	0.566	0.222	0.512	0.009
Rv2393.1	2	3bjw_SVR_H_504 PDB CREDO	0.566	0.222	0.512	0.009
Rv2393.2	1	4asd_BAX_A_1500 PDB CREDO	0.705	0.077	0.512	0.009
Rv2393.2	1	2j7y_E3O_A_1454 PDB CREDO	0.614	0.163	0.512	0.009
Rv2393.2	4	1mx1_THA_E_5 PDB CREDO	0.739	0.054	0.511	0.009
Rv2393.2	4	1p93_DEX_B_2999 PDB CREDO	0.641	0.133	0.511	0.009
Rv2393.1	2	3h52_486_D_2 PDB CREDO	0.792	0.028	0.511	0.009
Rv2393.1	2	3cyx_ROC_A_201 PDB CREDO	0.589	0.192	0.511	0.009
Rv2393.2	1	3f4x_KLT_A_300 PDB CREDO	0.613	0.164	0.511	0.009
Rv2393.2	1	3lfa_1N1_A_361 PDB CREDO	0.749	0.048	0.511	0.009
Rv2393.2	1	2w8y_NDR_B_1000 PDB CREDO	0.662	0.113	0.511	0.009
Rv2393.2	5	1pg2_ADN_A_552 PDB CREDO	0.511	0.302	0.511	0.009
Rv2393.2	1	3spk_TPV_B_100 PDB CREDO	0.724	0.064	0.510	0.009
Rv2393.2	4	3tkd_CYZ_B_267 PDB CREDO	0.510	0.303	0.510	0.009
Rv2393.2	1	2itz_IRE_A_2021 PDB CREDO	0.688	0.090	0.510	0.009
Rv2393.2	1	2w8y_486_A_1000 PDB CREDO	0.702	0.079	0.510	0.009
Rv2393.2	5	3lfa_1N1_A_361 PDB CREDO	0.636	0.139	0.509	0.010
Rv2393.2	1	3ads_IMN_A_2 PDB CREDO	0.509	0.305	0.509	0.010
Rv2393.1	2	1hxw_RIT_B_301 PDB CREDO	0.562	0.227	0.509	0.010
Rv2393.2	5	1qku_EST_A_600 PDB CREDO	0.533	0.269	0.508	0.010
Rv2393.2	1	3tkd_CYZ_A_266 PDB CREDO	0.620	0.156	0.508	0.010
Rv2393.1	2	1c6y_MK1_B_524 PDB CREDO	0.608	0.170	0.508	0.010
Rv2393.1	2	3bjw_SVR_E_503 PDB CREDO	0.607	0.171	0.507	0.010
Rv2393.2	4	3d90_NOG_A_1001 PDB CREDO	0.614	0.162	0.507	0.010
Rv2393.2	5	1ere_EST_E_600 PDB CREDO	0.530	0.272	0.506	0.010
Rv2393.2	5	1qku_EST_B_600 PDB CREDO	0.530	0.272	0.506	0.010
Rv2393.2	5	1qku_EST_C_600 PDB CREDO	0.530	0.272	0.506	0.010
Rv2393.1	2	3bjw_SVR_F_502 PDB CREDO	0.560	0.230	0.506	0.010
Rv2393.1	2	3cs9_NIL_C_600 PDB CREDO	0.590	0.191	0.506	0.010
Rv2393.2	4	3d90_NOG_B_2001 PDB CREDO	0.613	0.164	0.506	0.010
Rv2393.1	2	3cs9_NIL_D_600 PDB CREDO	0.589	0.192	0.506	0.010
Rv2393.2	5	1g50_EST_B_1600 PDB CREDO	0.529	0.274	0.505	0.010
Rv2393.2	4	1uwj_BAX_B_1723 PDB CREDO	0.537	0.263	0.505	0.010
Rv2393.2	4	2oiq_STI_A_1001 PDB CREDO	0.521	0.286	0.505	0.010
Rv2393.2	1	3aod_RFP_C_2002 PDB CREDO	0.562	0.227	0.505	0.010
Rv2393.1	2	2nni_MTK_A_501 PDB CREDO	0.714	0.070	0.505	0.010
Rv2393.2	1	1ie4_T44_B_328 PDB CREDO	0.629	0.146	0.505	0.010
Rv2393.2	5	1ere_EST_A_600 PDB CREDO	0.528	0.275	0.504	0.010
Rv2393.2	5	4dt8_ADN_A_401 PDB CREDO	0.553	0.240	0.504	0.010
Rv2393.1	2	3ut5_LOC_B_502 PDB CREDO	0.779	0.033	0.503	0.010
Rv2393.2	4	1sqn_NDR_A_1001 PDB CREDO	0.676	0.100	0.503	0.010
Rv2393.2	5	3ilt_TRU_E_800 PDB CREDO	0.554	0.239	0.503	0.010
Rv2393.2	1	3o1c_ADN_A_127 PDB CREDO	0.559	0.232	0.502	0.011
Rv2393.2	5	1ere_EST_B_600 PDB CREDO	0.526	0.279	0.502	0.011
Rv2393.2	4	1ya4_CTX_A_1 PDB CREDO	0.796	0.026	0.502	0.011
Rv2393.2	1	3k2h_LYA_B_514 PDB CREDO	0.519	0.288	0.502	0.011
Rv2393.2	4	3lzv_017_A_200 PDB CREDO	0.597	0.182	0.501	0.011
Rv2393.1	2	3ekx_1UN_B_201 PDB CREDO	0.540	0.258	0.501	0.011
Rv2393.2	4	3kk6_CEL_B_1701 PDB CREDO	0.631	0.144	0.501	0.011
Rv2393.2	1	3nrr_D16_B_520 PDB CREDO	0.501	0.317	0.501	0.011
Rv2393.1	2	3cs9_NIL_B_600 PDB CREDO	0.616	0.161	0.501	0.011
Rv2393.2	4	1sqn_NDR_B_2001 PDB CREDO	0.673	0.103	0.501	0.011
Rv2393.2	4	2o4n_TPV_A_300 PDB CREDO	0.501	0.317	0.501	0.011
Rv2393.2	4	3h52_486_C_4 PDB CREDO	0.697	0.083	0.501	0.011
Rv2393.2	1	3heg_BAX_A_1 PDB CREDO	0.669	0.106	0.500	0.011

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

Chemical Name	Confidence score	Molecular Weight
sirohemePubChem	0.711	916.661