Rv2362c

Tuberculist information
Gene namerecO
Protein functionPossible DNA repair protein RecO
Functional category(tuberculist)information pathways
Gene location(kb)2643.46
Molecular mass(da)28723.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 265
	  		  	1    MRLYRDRAVVLRQHKLGEADRIVTLLTRDHGLVRAVAKGVRRTRSKFGARLEPFAHIEVQ   60
			  	61   LHPGRNLDIVTQVVSVDAFATDIVADYGRYTCGCAILETAERLAGEERAPAPALHRLTVG  120
			  	121  ALRAVADGQRPRDLLLDAYLLRAMGIAGWAPALTECARCATPGPHRAFHIATGGSVCAHC  180
			  	181  RPAGSTTPPLGVVDLMSALYDGDWEAAEAAPQSARSHVSGLVAAHLQWHLERQLKTLPLV  240
			  	241  ERFYQADRSVAERRAALIGQDIAGG

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 1 to 79  |  Coverage: 29% RecO_N Range: 84 to 238  |  Coverage: 58% RecO_C Range: 2 to 240  |  Coverage: 89% 1 Range: to   |  Coverage: 0% 1
Number of amino acids : 265
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
RecO_NPF119671-79
RecO_CPF0256584-238
Mtb Structural Proteome models
Model Number1
Model nameRv2362c
Template1U5K    APDBCREDO
Template coverage4_235
Template Identity(%)24.2
Model coverage(%)89.8
Normalized DOPE score0.181

Structure Models from Chopin
Model Number1
Profileg.45.1.2
Click for model details
zscore17.92
Residue begin
Residue end
Binding pockets
STRING
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Protein interacting with Rv2362cGene nameConfidence Score
Rv3715crecR0.996
Rv3715crecR0.996
Rv3715crecR0.996
Rv0003recF0.981
Rv1696recN0.948
Rv2592cruvB0.934
Rv2592cruvB0.934
Rv3674cnth0.933
Rv3674cnth0.933
Rv3674cnth0.933
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions