Rv2320c

Tuberculist information
Gene namerocE
Protein functionProbable cationic amino acid transport integral membrane protein RocE
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2592.72
Molecular mass(da)49928.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 476
	  		  	1    LPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQA   60
			  	61   VPEAGPGVIVSFIIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLL  120
			  	121  LEYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHPGWVNLPAVILIGLCALL  180
			  	181  LIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSADHLKDFVPFGVAGIGSAAGTIFFS  240
			  	241  YIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQPWQDFAEQETAGL  300
			  	301  AIILDNVTHGEWASTILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRT  360
			  	361  MTPVHNTVIVAIFASTLAAFIPLDSLADMVSIGTLTAFSVVAVGVIVLRVREPDLPRGFK  420
			  	421  VPGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSALNEEVP

Known structures in the PDB
No Known structures
1 48 95 142 189 236 283 330 377 424 471 Range: 35 to 469  |  Coverage: 91% AA_permease_2 Range: 46 to 468  |  Coverage: 88% 1
Number of amino acids : 476
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
AA_permease_2PF1352035-469
Mtb Structural Proteome models
Model Number1
Model nameRv2320c
Template2A65    APDBCREDO
Template coverage20_509
Template Identity(%)20.6
Model coverage(%)88.7
Normalized DOPE score0.486

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2320cGene nameConfidence Score
Rv2322crocD10.976
Rv2319cRv2319c0.934
Rv2321crocD20.922
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
ornithinePubChem0.926132.161