Rv1655

Tuberculist information
Gene nameargD
Protein functionProbable acetylornithine aminotransferase ArgD
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1868.72
Molecular mass(da)40909.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 400
	  		  	1    MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVTDVDGRTYIDLLGGIAVNVLGH   60
			  	61   RHPAVIEAVTRQMSTLGHTSNLYATEPGIALAEELVALLGADQRTRVFFCNSGAEANEAA  120
			  	121  FKLSRLTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAA  180
			  	181  VDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQ  240
			  	241  HDGITPDVVTLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVL  300
			  	301  ASDGLVRRAEVLGKSLRHGIEALGHPLIDHVRGRGLLLGIALTAPHAKDAEATARDAGYL  360
			  	361  VNAAAPDVIRLAPPLIIAEAQLDGFVAALPAILDRAVGAP

Known structures in the PDB
No Known structures
1 41 81 121 161 201 241 281 321 361 401 Range: 29 to 344  |  Coverage: 78% Aminotran_3 Range: 10 to 394  |  Coverage: 96% 1 Range: 1 to 400  |  Coverage: 99% 1
Number of amino acids : 400
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Aminotran_3PF0020229-344
Mtb Structural Proteome models
Model Number1
Model nameRv1655
Template1VEF    APDBCREDO
Template coverage11_395
Template Identity(%)43.6
Model coverage(%)96.0
Normalized DOPE score-0.312

Structure Models from Chopin
Model Number1
Profilec.67.1.4
Click for model details
zscore28.76
Residue begin1
Residue end400
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1655Gene nameConfidence Score
Rv1652argC0.999
Rv1653argJ0.999
Rv1654argB0.999
Rv1652argC0.999
Rv1658argG0.997
Rv1656argF0.997
Rv1656argF0.997
Rv1659argH0.987
Rv1659argH0.987
Rv1657argR0.952
Rv1657argR0.952
Rv2753cdapA0.913
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
ornithinePubChem0.97132.161
acetylornithinePubChem0.939174.198
glutamatePubChem0.935147.129
alpha-ketoglutaratePubChem0.933146.098
N-acetylglutamatePubChem0.93189.166
N-acetyl-L-glutamic acid gamma-semialdehydePubChem0.909173.167
NADPPubChem0.904744.413
phosphatePubChem0.90396.9872
NADP(H)PubChem0.902745.421
hydroxyl radicalsPubChem0.90117.0073
H(+)PubChem0.92.01588
N-acetyl-L-glutamyl-5-phosphatePubChem0.9269.146
protiumPubChem0.92.01576
acetatePubChem0.959.044
deuteriumPubChem0.92.01588
N-acetylglutamyl-phosphatePubChem0.9269.146
pyridoxal phosphatePubChem0.817247.142