Rv1422

Tuberculist information
Gene nameRv1422
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)1596.88
Molecular mass(da)35823.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 342
	  		  	1    MTDGIVALGGGHGLYATLSAARRLTPYVTAVVTVADDGGSSGRLRSELDVVPPGDLRMAL   60
			  	61   AALASDSPHGRLWATILQHRFGGSGALAGHPIGNLMLAGLSEVLADPVAALDELGRILGV  120
			  	121  KGRVLPMCPVALQIEADVSGLEADPRMFRLIRGQVAIATTPGKVRRVRLLPTDPPATRQA  180
			  	181  VDAIMAADLVVLGPGSWFTSVIPHVLVPGLAAALRATSARRALVLNLVAEPGETAGFSVE  240
			  	241  RHLHVLAQHAPGFTVHDIIIDAERVPSEREREQLRRTATMLQAEVHFADVARPGTPLHDP  300
			  	301  GKLAAVLDGVCARDVGASEPPVAATQEIPIDGGRPRGDDAWR

Known structures in the PDB
No Known structures
1 35 69 103 137 171 205 239 273 307 341 Range: 5 to 302  |  Coverage: 86% UPF0052 Range: 5 to 313  |  Coverage: 90% 1 Range: 1 to 314  |  Coverage: 91% 1 Range: 85 to 303  |  Coverage: 63% 2
Number of amino acids : 342
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
UPF0052PF019335-302
Mtb Structural Proteome models
Model Number1
Model nameRv1422
Template2FFE    APDBCREDO
Template coverage1_305
Template Identity(%)18.0
Model coverage(%)90.1
Normalized DOPE score0.677

Structure Models from Chopin
Model Number1
Profilec.143.1.1
Click for model details
zscore42.3
Residue begin1
Residue end314
Model Number2
Profile3.40.50.10680
Click for model details
zscore15.04
Residue begin85
Residue end303
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1422Gene nameConfidence Score
Rv1423whiA0.989
Rv1423whiA0.989
Rv1423whiA0.989
Rv1421Rv14210.989
Rv1420uvrC0.937
Rv1420uvrC0.937
Rv1420uvrC0.937
Rv1420uvrC0.937
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
selenomethioninePubChem0.799196.106
SeMetPubChem0.799196.106
phosphatePubChem0.74396.9872