SInCRe - Rv0976c

Tuberculist information

Gene name	Rv0976c
Protein function	Conserved hypothetical protein
Functional category(tuberculist)	conserved hypotheticals
Gene location(kb)	1088.49
Molecular mass(da)	59091
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 560

	  		  	1    VRIGNCSGFYGDRLSAMREMLTGGELDYLTGDYLAELTMLILGRDRMKNPDRGYAKTFLA   60
			  	61   QLEDCLGLAHDRGVRIVTNAGGLNPAGLANAVRALAARLGIPAQVAHVEGDDLQPRAAEL  120
			  	121  GLGTPLTANAYLGAWGIVDCFERGADVVVTGRVTDASVVVGAAAAHFGWGRTDYHRLAGA  180
			  	181  VVAGHVIECGVQATGGNYAFFTEIGDLTHAGFPLAEIAADGSSVITKHHGTGGLVSVDTI  240
			  	241  TAQLLYEITGARYANPDVTARMDSVELSPDGPDRVRISGVIGEPPPPTYKVSLNSIGGFR  300
			  	301  NAMTFVLTGLDIDAKADLVRRQLEAALTVKPAELQWTLARTDHPDADTEETASALLTCVA  360
			  	361  RDPDPANVGRQFSSAAVELALASYPGFTATAPPGDGQVYGVFTPGYVDAGKVAHIAVHAD  420
			  	421  GTRTEIPCATETLELAPAHPPALPDPLPAGPTRRVPLGLIAGARSGDKGGSANVGVWVRT  480
			  	481  DEQWRWLAHTLTVELLKELLPETAGLVVTRHVLPNLRALNFVIEAILGQGVAYQARFDPQ  540
			  	541  AKGLGEWLRSRHVEIPETLL

Known structures in the PDB

No Known structures

Number of amino acids : 560

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
DUF1446	PF07287	3-340

Mtb Structural Proteome models

Structure models not available for this query

Structure Models from Chopin

CHOPIN models not available for this query

Binding pockets

Structure models not available for this query

STRING

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Protein interacting with Rv0976c	Gene name	Confidence Score
Rv0974c	accD2	0.973
Rv0971c	echA7	0.965
Rv0973c	accA2	0.964
Rv0972c	fadE12	0.964
Rv0972c	fadE12	0.964
Rv0972c	fadE12	0.964
Rv0973c	accA2	0.964
Rv0973c	accA2	0.964
Rv0973c	accA2	0.964
Rv0975c	fadE13	0.95
Rv0975c	fadE13	0.95
Rv0975c	fadE13	0.95

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

No high confidence interactions