Rv0937c

Tuberculist information
Gene namemku
Protein functionDNA end-binding protein, Mku
Functional category(tuberculist)information pathways
Gene location(kb)1045.2
Molecular mass(da)30904
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 273
	  		  	1    MRAIWTGSIAFGLVNVPVKVYSATADHDIRFHQVHAKDNGRIRYKRVCEACGEVVDYRDL   60
			  	61   ARAYESGDGQMVAITDDDIASLPEERSREIEVLEFVPAADVDPMMFDRSYFLEPDSKSSK  120
			  	121  SYVLLAKTLAETDRMAIVHFTLRNKTRLAALRVKDFGKREVMMVHTLLWPDEIRDPDFPV  180
			  	181  LDQKVEIKPAELKMAGQVVDSMADDFNPDRYHDTYQEQLQELIDTKLEGGQAFTAEDQPR  240
			  	241  LLDEPEDVSDLLAKLEASVKARSKANSNVPTPP

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 9 to 195  |  Coverage: 68% Ku Range: 5 to 273  |  Coverage: 98% 1 Range: 2 to 267  |  Coverage: 97% 1
Number of amino acids : 273
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
KuPF027359-195
Mtb Structural Proteome models
Model Number1
Model nameRv0937c
Template1JEY    BPDBCREDO
Template coverage247_544
Template Identity(%)13.0
Model coverage(%)97.8
Normalized DOPE score0.962

Structure Models from Chopin
Model Number1
Profileb.131.1.1
Click for model details
zscore16.43
Residue begin2
Residue end267
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0937cGene nameConfidence Score
Rv0938ligD0.991
Rv0938ligD0.991
Rv0938ligD0.991
Rv0938ligD0.991
Rv3730cRv3730c0.959
Rv0269cRv0269c0.932
Rv3731ligC0.929
Rv3731ligC0.929
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions