Rv0269c

Tuberculist information
Gene nameRv0269c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)323.338
Molecular mass(da)44040.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 397
	  		  	1    MSRMAAPVSLDVHGRQVIVTHPGRVVFPAHNDRKGYTKFDLVRYYLAVAEGAMRGVAGRP   60
			  	61   MILKRFVKGISAEAVFQKRAPANRPDWVDVAELHYASGRSAAEAVIHDAAGLAWVINLGC  120
			  	121  VDLNPHPVLAGDLDHPDELRVDLDPMPGVAWQRVVEVALVVREVLEDYGLTAWPKTSGSR  180
			  	181  GFHVYARIAPCWSFPQVRLAAQTVAREVERRLPDAATSRWWKEEREGVFVDFNQNAKDRT  240
			  	241  VASAYSVRATPDARVSTPLHWEEVPGCDPAVFTMATVPSRLADIGDPWAGMDDAVGRLDR  300
			  	301  LLMLAEELGPPQKAQSAKPLIEIARAKTRAEAMAALDIWRDRYPGAAALLRPADVLVDGM  360
			  	361  RGPSSIWYRIRINLQHVPADQRPPQEELIADYSPWPR

Known structures in the PDB
No Known structures
1 40 79 118 157 196 235 274 313 352 391 Range: 132 to 261  |  Coverage: 32% DNA_primase_S Range: 13 to 303  |  Coverage: 73% 1
Number of amino acids : 397
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DNA_primase_SPF01896132-261
Mtb Structural Proteome models
Model Number1
Model nameRv0269c
Template2FAO    APDBCREDO
Template coverage545_834
Template Identity(%)25.9
Model coverage(%)73.0
Normalized DOPE score-0.267

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0269cGene nameConfidence Score
Rv3731ligC0.945
Rv3731ligC0.945
Rv0937cmku0.932
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions