Rv0085

Tuberculist information
Gene namehycP
Protein functionPossible hydrogenase HycP
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)93.289
Molecular mass(da)23042.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 220
	  		  	1    MSNANFSILVDFAAGGLVLASVLIVWRRDLRAIVRLLAWQGAALAAIPLLRGIRDNDRAL   60
			  	61   IAVGIAVLALRALVLPWLLARAVGAEAAAQREATPLVNTASSLLITAGLTLTAFAITQPV  120
			  	121  VNLEPGVTINAVPAAFAVVLIALFVMTTRLHAVSQAAGFLMLDNGIAATAFLLTAGVPLI  180
			  	181  VELGASLDVLFAVIVIGVLTGRLRRIFGDADLDKLRELRD

Known structures in the PDB
No Known structures
1 23 45 67 89 111 133 155 177 199 221 Range: 3 to 220  |  Coverage: 98% 1
Number of amino acids : 220
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Domain assignments not available for this query
Mtb Structural Proteome models
Model Number1
Model nameRv0085
Template1YO8    APDBCREDO
Template coverage968_1171
Template Identity(%)7.8
Model coverage(%)98.6
Normalized DOPE score1.671

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0085Gene nameConfidence Score
Rv0086hycQ0.999
Rv0087hycE0.999
Rv0087hycE0.999
Rv0087hycE0.999
Rv0084hycD0.995
Rv0083Rv00830.994
Rv0082Rv00820.989
Rv2455cRv2455c0.934
Rv2455cRv2455c0.934
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
pyruvic acidPubChem0.988.0621
H(+)PubChem0.92.01588
protiumPubChem0.92.01576
carbon dioxidePubChem0.944.0095
deuteriumPubChem0.92.01588
acetyl coenzyme-APubChem0.9809.571
Co-APubChem0.9767.534
acetyl-CoAPubChem0.9809.571
coenzyme APubChem0.9767.534