Rv0083

Tuberculist information
Gene nameRv0083
Protein functionProbable oxidoreductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)90.4
Molecular mass(da)65627.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 640
	  		  	1    MTAAPTAGGVVTSGVGVAGVGVGLLGMFGPVRVVHVGWLLPLSGVHIELDRLGGFFMALT   60
			  	61   GAVAAPVGCYLIGYVRREHLGRVPMAVVPLFVAAMLLVPAAGSVTTFLLAWELMAIASLI  120
			  	121  LVLSEHARPQVRSAGLWYAVMTQLGFIAILVGLVVLAAAGGSDRFAGLGAVCDGVRAAVF  180
			  	181  MLTLVGFGSKAGLVPLHAWLPRAHPEAPSPVSALMSAAMVNLGIYGIVRFDLQLLGPGPR  240
			  	241  WWGLALLAVGGTSALYGVLQASVAADLKRLLAYSTTENMGLITLALGAATLFADTGAYGP  300
			  	301  ASIAAAAAMLHMIAHAAFKSLAFMAAGSVLAATGLRDLDLLGGLARRMPATTVFFGVAAL  360
			  	361  GACGLPLGAGFVSEWLLVQSLIHAAPGHDPIVALTTPLAVGVVALATGLSVAAMTKAFGI  420
			  	421  GFLARPRSTQAEAAREAPASMRAGMAIAAGACLVLAVAPLLVAPMVRRAAATLPAAQAVK  480
			  	481  FTGLGAVVRLPAMSGSIAPGVIAAAVLAAALAVAVLARWRFRRRPAPARLPLWACGAADL  540
			  	541  TVRMQYTATSFAEPLQRVFGDVLRPDTDIEVTHTAESRYMAERITYRTAVADAIEQRLYT  600
			  	601  PVVGAVAAMAELLRRAHTGSVHRYLAYGALGVLIVLVVAR

Known structures in the PDB
No Known structures
1 65 129 193 257 321 385 449 513 577 641 Range: 101 to 381  |  Coverage: 43% Oxidored_q1 Range: 14 to 392  |  Coverage: 59% 1
Number of amino acids : 640
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Oxidored_q1PF00361101-381
Mtb Structural Proteome models
Model Number1
Model nameRv0083
Template1V54    APDBCREDO
Template coverage110_505
Template Identity(%)10.0
Model coverage(%)59.1
Normalized DOPE score2.039

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0083Gene nameConfidence Score
Rv0084hycD0.996
Rv0082Rv00820.995
Rv0087hycE0.994
Rv0087hycE0.994
Rv0085hycP0.994
Rv0087hycE0.994
Rv0086hycQ0.975
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions