Rv3600c

Tuberculist information
Gene nameRv3600c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)4043.04
Molecular mass(da)29272.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 272
	  		  	1    VLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTG   60
			  	61   TAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAY  120
			  	121  DRFRKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELARPRS  180
			  	181  VVGKNTVECMQAGAVFGFAGLVDGLVGRIREDVSGFSVDHDVAIVATGHTAPLLLPELHT  240
			  	241  VDHYDQHLTLQGLRLVFERNLEVQRGRLKTAR

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 2 to 208  |  Coverage: 75% Pan_kinase Range: 1 to 255  |  Coverage: 93% 1 Range: 125 to 263  |  Coverage: 50% 1
Number of amino acids : 272
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Pan_kinasePF033092-208
Mtb Structural Proteome models
Model Number1
Model nameRv3600c
Template2GTD    APDBCREDO
Template coverage4_244
Template Identity(%)31.9
Model coverage(%)93.4
Normalized DOPE score-0.213

Structure Models from Chopin
Model Number1
Profilec.55.1.13
Click for model details
zscore13.35
Residue begin125
Residue end263
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3600cGene nameConfidence Score
Rv1391dfp0.998
Rv1391dfp0.998
Rv3602cpanC0.998
Rv2965ckdtB0.995
Rv3601cpanD0.988
Rv1092ccoaA0.987
Rv3603cRv3603c0.956
Rv3603cRv3603c0.956
Rv2225panB0.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
pantothenic acidPubChem0.992219.235
4'-phosphopantothenatePubChem0.965299.215
4'-phosphopantetheinePubChem0.903358.348
4'-phosphopantothenoylcysteinePubChem0.9402.358
coenzyme APubChem0.799767.534
polyethylene glycolPubChem0.762.0678
ethylene glycol; hydronPubChem0.763.0758