Tuberculist information
Gene nameRv3603c
Protein functionConserved hypothetical alanine and leucine rich protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)4045.21
Molecular mass(da)31104.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 303
	  		  	1    MERFDGLRPARLKVGIISAGRVGTALGVALQRADHVVVACSAISHASRRRAQRRLPDTPV   60
			  	61   LPPLDVAASAELLLLAVTDSELAGLVSGLAATSAVRPQTIVAHTSGANGIGILAPLAQQG  120
			  	121  CIPLAIHPAMTFTGSDEDISRLPDTCFGITAADDVGYAIGQSLVLEMGGEPFCVREDARI  180
			  	181  LYHAALAHASNHIVTVLADALEALRAALSGGELLGQQTVDDQPGGIVERIVGPLARAALE  240
			  	241  NTLQRGQAALTGPVARGDAAAVADHLAALADVDAALAQAYRINALRTAQRAHAPADVVEV  300
			  	301  LTA
			  			

Known structures in the PDB
No Known structures
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Rossmann-likePF107271-128
DUF2520PF10728144-288
Mtb Structural Proteome models
Model Number1
Model nameRv3603c
Template1NP3    APDBCREDO
Template coverage3_297
Template Identity(%)14.1
Model coverage(%)95.7
Normalized DOPE score0.78

Structure Models from Chopin
Model Number1
Profile1.10.1040.20, 3.40.50.720
Click for model details
zscore31.64
Residue begin8
Residue end291
Model Number2
Profilea.100.1.10
Click for model details
zscore21.83
Residue begin179
Residue end298
Model Number3
Profilec.2.1.6 - 3.40.50.720
Click for model details
zscore10.48
Residue begin11
Residue end128
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3603cGene nameConfidence Score
Rv3602cpanC0.996
Rv3601cpanD0.968
Rv3600cRv3600c0.956
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions